Environmental sampling coupled with real-time PCR and genotyping to investigate the source of a Q fever outbreak in a work setting.

Abstract:

:A Q fever outbreak was declared in February 2016 in a company that manufactures hoists and chains and therefore with no apparent occupational-associated risk. Coxiella burnetii infection was diagnosed by serology in eight of the 29 workers of the company; seven of them had fever or flu-like signs and five had pneumonia, one requiring hospitalisation. A further case of C. burnetii pneumonia was diagnosed in a local resident. Real-time PCR (RTi-PCR) showed a widespread distribution of C. burnetii DNA in dust samples collected from the plant facilities, thus confirming the exposure of workers to the infection inside the factory. Epidemiological investigations identified a goat flock with high C. burnetii seroprevalence and active shedding which was owned and managed by one of the workers of the company as possible source of infection. Genotyping by multispacer sequence typing (MST) and a 10-loci single-nucleotide polymorphism (SNP) discrimination using RTi-PCR identified the same genotype (MST18 and SNP type 8, respectively) in the farm and the factory. These results confirmed the link between the goat farm and the outbreak and allowed the identification of the source of infection. The circumstances and possible vehicles for the bacteria entering the factory are discussed.

journal_name

Epidemiol Infect

authors

Hurtado A,Alonso E,Aspiritxaga I,López Etxaniz I,Ocabo B,Barandika JF,Fernández-Ortiz DE Murúa JI,Urbaneja F,Álvarez-Alonso R,Jado I,García-Pérez AL

doi

10.1017/S0950268817000796

subject

Has Abstract

pub_date

2017-07-01 00:00:00

pages

1834-1842

issue

9

eissn

0950-2688

issn

1469-4409

pii

S0950268817000796

journal_volume

145

pub_type

杂志文章
  • Hepatitis B virus infection in general population in Madagascar: evidence for different epidemiological patterns in urban and in rural areas.

    abstract::To describe the features of hepatitis B virus (HBV) infection in Madagascar, a randomized sero-epidemiological survey was undertaken in the general population > or = 1 year old of two provinces which represents 45% of the total population. In the 921 sera tested, the prevalence of HBV markers was 20.5% for HBsAg, 38.2...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800001229

    authors: Boisier P,Rabarijaona L,Piollet M,Roux JF,Zeller HG

    更新日期:1996-08-01 00:00:00

  • Transmission of respiratory and gastrointestinal infections in German households with children attending child care.

    abstract::Transmission of acute respiratory infections (ARI) and acute gastroenteritis (AGE) often occurs in households. The aim of this study was to assess which proportion of ARI and AGE is introduced and transmitted by children in German households with children attending child care. We recruited families with children aged ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268818000316

    authors: Schlinkmann KM,Bakuli A,Karch A,Meyer F,Dreesman J,Monazahian M,Mikolajczyk R

    更新日期:2018-04-01 00:00:00

  • The effectiveness of Haemophilus influenzae type b conjugate vaccines in a high risk population measured using immunization register data.

    abstract::The Northern Territory of Australia has had historically very high incidence rates of invasive Haemophilus influenzae type b disease in children less than 5 years of age, with the burden of disease greatest among Aboriginal infants less than 12 months. This study documents the impact of conjugate Hib vaccines introduc...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268801005155

    authors: Markey P,Krause V,Boslego JW,Coplan PM,Dargan JM,Kaplan KM

    更新日期:2001-02-01 00:00:00

  • Salmonella Enteritidis outbreak associated with a school-lunch dessert: cross-contamination and a long incubation period, Japan, 2001.

    abstract::A Salmonella Enteritidis (SE) outbreak in Japan was investigated with an observational study, analytical epidemiology and bacteriological examination (including phage typing). The outbreak occurred among 96 schoolchildren, and was caused by SE phage type 1. The outbreak source was dessert buns served at a school lunch...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268804002778

    authors: Matsui T,Suzuki S,Takahashi H,Ohyama T,Kobayashi J,Izumiya H,Watanabe H,Kasuga F,Kijima H,Shibata K,Okabe N

    更新日期:2004-10-01 00:00:00

  • Measles in developing countries. Part I. Epidemiological parameters and patterns.

    abstract::This paper presents a review of published data concerning the epidemiology of measles in developing countries. Simple mathematical models provide a framework for data analysis and interpretation. The analyses highlight differences and similarities in the patterns of transmission of the measles virus in developed and d...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800065614

    authors: McLean AR,Anderson RM

    更新日期:1988-02-01 00:00:00

  • Salivary diagnosis of rubella: a study of notified cases in the United Kingdom, 1991-4.

    abstract::Rubella infections, notified by general practitioners on the basis of a clinical diagnosis, were investigated by testing blood and saliva samples for specific IgM. Overall 52 (29%) of 178 cases with appropriately timed blood specimens were confirmed as recent rubella by IgM serology. Only 2 (3%) of 74 cases in childre...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268898008838

    authors: Ramsay ME,Brugha R,Brown DW,Cohen BJ,Miller E

    更新日期:1998-06-01 00:00:00

  • The multifaceted role of mobile technologies as a strategy to combat COVID-19 pandemic.

    abstract::The coronavirus 2019 (COVID-19) outbreak in China rapidly spread throughout the world, becoming a threatening pandemic with unprecedented consequences. Mobile technologies have led to a revolution in health and their applicability in the context of COVID-19 is promising. In this commentary, we provide an overview of t...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268820002435

    authors: Teixeira R,Doetsch J

    更新日期:2020-10-13 00:00:00

  • Usefulness of seroconversion rates for comparing infection pressures between countries.

    abstract::Salmonella is a frequent cause of foodborne illness. However, since most symptomatic cases are not diagnosed, the true infection pressure is unknown. Furthermore, national surveillance systems have different sensitivities that limit inter-country comparisons. We have used recently developed methods for translating mea...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268810000750

    authors: Simonsen J,Teunis P,van Pelt W,van Duynhoven Y,Krogfelt KA,Sadkowska-Todys M,Mølbak K

    更新日期:2011-04-01 00:00:00

  • Impact of respiratory virus infection in patients with chronic chest disease.

    abstract::This study investigated the morbidity associated with respiratory virus infections in patients with well-documented chest disease, and the risk of transmission between close contacts. Patients informed the study team if they were exposed to a family member or colleague with a cold. Patients and symptomatic index cases...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800057046

    authors: Wiselka MJ,Kent J,Cookson JB,Nicholson KG

    更新日期:1993-10-01 00:00:00

  • The speciation and subtyping of campylobacter isolates from sewage plants and waste water from a connected poultry abattoir using molecular techniques.

    abstract::In this study the distribution of phenotypes of campylobacter strains in sewage and surface waters was investigated by subtyping and by speciation of isolates from various aquatic environments. These environments included two municipal sewage plants (SPA and SPB) and waste water from a poultry abattoir (WWA). Both the...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800058647

    authors: Koenraad PM,Ayling R,Hazeleger WC,Rombouts FM,Newell DG

    更新日期:1995-12-01 00:00:00

  • In vitro virucidal activity of sodium hypochlorite against canine parvovirus type 2.

    abstract::Canine parvovirosis is a very contagious, severe and often lethal infectious disease of dogs caused by canine parvovirus type 2 (CPV-2). Parvoviruses are very resistant to several disinfectants while are sensitive to halogens such as sodium hypochlorite which is often used for decontamination of veterinary clinics and...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268818002431

    authors: Cavalli A,Marinaro M,Desario C,Corrente M,Camero M,Buonavoglia C

    更新日期:2018-11-01 00:00:00

  • Pseudomonas aeruginosa dose response and bathing water infection.

    abstract::Pseudomonas aeruginosa is the opportunistic pathogen mostly implicated in folliculitis and acute otitis externa in pools and hot tubs. Nevertheless, infection risks remain poorly quantified. This paper reviews disease aetiologies and bacterial skin colonization science to advance dose-response theory development. Thre...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,评审

    doi:10.1017/S0950268813002690

    authors: Roser DJ,van den Akker B,Boase S,Haas CN,Ashbolt NJ,Rice SA

    更新日期:2014-03-01 00:00:00

  • Serotype distribution of Streptococcus pneumoniae causing invasive disease in the Republic of Ireland.

    abstract::The 7-valent pneumococcal conjugate vaccine (PCV7) was included in the routine infant immunization schedule in Ireland in September 2008. We determined the serotype of 977 S. pneumoniae isolates causing invasive disease between 2000-2002 and 2007-2008, assessed for the presence of the recently described serotype 6C an...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268810001743

    authors: Vickers I,Fitzgerald M,Murchan S,Cotter S,O'Flanagan D,Cafferkey M,Humphreys H

    更新日期:2011-05-01 00:00:00

  • Transmission of bovine herpesvirus 1 within and between herds on an island with a BHV1 control programme.

    abstract::Transmission of bovine herpesvirus 1 (BHV1) within and between herds was studied on the island of Ameland, The Netherlands. There were 50 herds with 3300 head of cattle on the island. Herds were divided into three groups: (1) only containing seronegative cattle, (2) containing seronegative cattle and vaccinated seropo...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:

    authors: Hage JJ,Schukken YH,Schols H,Maris-Veldhuis MA,Rijsewijk FA,Klaassen CH

    更新日期:2003-06-01 00:00:00

  • West Nile virus-neutralizing antibodies in wild birds from southern Spain.

    abstract::West Nile virus (WNV) is an emerging vector-borne arbovirus with a zoonotic life-cycle whose main reservoir hosts are birds. In humans and horses, WNV infections rarely result in clinical disease but on occasions - depending on factors such as climatic conditions, insect communities and background immunity levels in l...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268816000133

    authors: Ferraguti M,LA Puente JM,Soriguer R,Llorente F,Jiménez-Clavero MÁ,Figuerola J

    更新日期:2016-07-01 00:00:00

  • Prevalence of and risk factors for MRSA carriage in companion animals: a survey of dogs, cats and horses.

    abstract::We investigated the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) carriage in a convenience sample of purposely selected populations of dogs, cats and horses in the Greater London area. Swabs from carriage sites were pooled, enriched and processed by standard bacteriological methods. The presence of...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026881000227X

    authors: Loeffler A,Pfeiffer DU,Lindsay JA,Soares Magalhães RJ,Lloyd DH

    更新日期:2011-07-01 00:00:00

  • Neuroborreliosis in the South West of England.

    abstract::Although Lyme borreliosis is increasingly diagnosed in the United Kingdom, few systematic studies have been performed there. UK data suggest that the commonest complications are neurological, but inadequate information exists about their nature and the incidence of late neuroborreliosis. Local data are necessary becau...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268808000472

    authors: Lovett JK,Evans PH,O'Connell S,Gutowski NJ

    更新日期:2008-12-01 00:00:00

  • Varicella vaccine uptake and associated factors in children in Hong Kong.

    abstract::Varicella is a common and highly contagious childhood disease which impacts the public worldwide. Hong Kong children can only be vaccinated against the disease in private practice. The varicella vaccination rate of local children in preschool is uncertain. Therefore a cross-sectional kindergarten-based parent-administ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268813001994

    authors: Chan JY,Leung KM,Tam WW,Lee A

    更新日期:2014-05-01 00:00:00

  • Multiple sites of exposure in an outbreak of ornithosis in workers at a poultry abattoir and farm.

    abstract::Cases of ornithosis amongst workers on a rural duck abattoir and farm were notified from late 2003 to health authorities in Victoria, Australia. In May 2004 we conducted a serological survey to identify the extent of exposure to Chlamydophila psittaci amongst workers and a case control study to identify high-risk work...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026880700790X

    authors: Tiong A,Vu T,Counahan M,Leydon J,Tallis G,Lambert S

    更新日期:2007-10-01 00:00:00

  • Increase of immunity to rubella and interruption of rubella transmission in Gipuzkoa (Basque Country, Spain) after an enhanced vaccination programme.

    abstract::In Spain, vaccination against rubella was initiated in schoolgirls in the mid-1970s. In Gipuzkoa, subsequent extensions to the vaccination schedule culminated in 1992 with the introduction of the two-dose measles, mumps and rubella vaccine in children and adolescents of both sexes. Moreover, in 1985 a programme for th...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268804002158

    authors: Cilla G,Dorronsoro M,Sáenz-Domínguez JR,Serrano E,Pérez-Trallero E

    更新日期:2004-08-01 00:00:00

  • Application of multiblock modelling to identify key drivers for antimicrobial use in pig production in four European countries.

    abstract::Antimicrobial use in pig farming is influenced by a range of risk factors, including herd characteristics, biosecurity level, farm performance, occurrence of clinical signs and vaccination scheme, as well as farmers' attitudes and habits towards antimicrobial use. So far, the effect of these risk factors has been expl...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268818000742

    authors: Collineau L,Bougeard S,Backhans A,Dewulf J,Emanuelson U,Grosse Beilage E,Lehébel A,Lösken S,Postma M,Sjölund M,Stärk KDC,Visschers VHM,Belloc C

    更新日期:2018-06-01 00:00:00

  • Outbreak of Listeria monocytogenes infections linked to a pasteurized ice cream product served to hospitalized patients.

    abstract::Two cases of hospital-acquired listeriosis were linked to a commercially produced, pasteurized ice cream mix. Manufacturers should implement safety measures from the Food Safety Modernization Act to minimize the risk of Listeria contamination. Dietary guidelines for persons at high risk of listeriosis may need revisio...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268815003039

    authors: Rietberg K,Lloyd J,Melius B,Wyman P,Treadwell R,Olson G,Kang MG,Duchin JS

    更新日期:2016-10-01 00:00:00

  • A dot-blot hybridization procedure for the detection of astrovirus in stool samples.

    abstract::We have developed a nucleic acid dot-blot hybridization test for the detection of astroviruses in stool samples. The test was not as sensitive as electron microscopy for the detection of low numbers of well preserved astrovirus particles, but was able to identify astroviruses in stools containing particles of indistin...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800049049

    authors: Willcocks MM,Carter MJ,Silcock JG,Madeley CR

    更新日期:1991-10-01 00:00:00

  • Association between Toxoplasma gondii exposure and paediatrics haematological malignancies: a case-control study.

    abstract::The possible association between Toxoplasma gondii infection and paediatric haematological malignancies in a group of patients and control subjects was evaluated in the present study. We performed an age-, gender- and residence frequency-matched case-control study of 101 blood cancer patients under 18 years of age, al...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268818002194

    authors: Kalantari N,Rezanejad J,Tamadoni A,Ghaffari S,Alipour J,Bayani M

    更新日期:2018-11-01 00:00:00

  • Shifting dominance of Shigella species in men who have sex with men.

    abstract::Historically, Shigella sonnei has dominated other Shigella species infection in men who have sex with men (MSM) in Montréal. In early 2010, Toronto reported increased proportions of the more pathogenic S. flexneri, HIV co-infection and MSM in shigellosis cases since 2009. Analytical methods were used to assess whether...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268812000738

    authors: Ratnayake R,Allard R,Pilon PA

    更新日期:2012-11-01 00:00:00

  • Emergence of multidrug-resistant Salmonella enterica serotype Typhi with decreased ciprofloxacin susceptibility in Bangladesh.

    abstract::During 1989-2002, we studied the antimicrobial resistance of 3928 blood culture isolates of Salmonella enterica serotype Typhi (S. Typhi) in Dhaka, Bangladesh. Overall 32% (1270) of the strains were multidrug-resistant (MDR, resistant to chloramphenicol, ampicillin and trimethoprim-sulphamethoxazole); first detected i...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268805004759

    authors: Rahman M,Siddique AK,Shoma S,Rashid H,Salam MA,Ahmed QS,Nair GB,Breiman RF

    更新日期:2006-04-01 00:00:00

  • Concomitant leptospirosis-hantavirus co-infection in acute patients hospitalized in Sri Lanka: implications for a potentially worldwide underestimated problem.

    abstract::Two global (re-)emerging zoonoses, leptospirosis and hantavirus infections, are clinically indistinguishable. Thirty-one patients, hospitalized in Sri Lanka for acute severe leptospirosis, were after exclusion of other potentially involved pathogens, prospectively screened with IgM ELISA for both pathogens. Of these, ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814003707

    authors: Sunil-Chandra NP,Clement J,Maes P,DE Silva HJ,VAN Esbroeck M,VAN Ranst M

    更新日期:2015-07-01 00:00:00

  • Molecular epidemiology and genetic diversity of Campylobacter jejuni in ruminants.

    abstract::Multi-locus sequence typing was performed on 1003 Campylobacter jejuni isolates collected in a 2-year longitudinal study of 15 dairy farms and four sheep farms in Lancashire, UK. There was considerable farm-level variation in occurrence and prevalence of clonal complexes (CC). Clonal complexes ST61, ST21, ST403 and ST...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268810002736

    authors: Grove-White DH,Leatherbarrow AJ,Cripps PJ,Diggle PJ,French NP

    更新日期:2011-11-01 00:00:00

  • The seroepidemiology of Lyme borreliosis in zoo animals in Germany.

    abstract::We conducted the first seroepidemiological study to evaluate the exposure of zoo animals to Borrelia burgdorferi s.l. in German zoos and wildlife parks. A total of 1487 individuals representing 148 ungulate and carnivore species belonging to 19 families were examined using a non-species dependent ELISA. Specific antib...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268803008896

    authors: Stoebel K,Schoenberg A,Streich WJ

    更新日期:2003-10-01 00:00:00

  • Determining the ideal prevention strategy for multidrug-resistance organisms in resource-limited countries: a cost-effectiveness analysis study.

    abstract::The aim of this study was to determine the most cost-effective strategy for the prevention and control of multidrug-resistant organisms (MDROs) in intensive care units (ICUs) in areas with limited health resources. The study was conducted in 12 ICUs of four hospitals. The total cost for the prevention of MDROs and the...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268820001120

    authors: Wang Y,Yuan Y,Lin L,Tan X,Tan Y

    更新日期:2020-05-20 00:00:00