Abstract:
:The 7-valent pneumococcal conjugate vaccine (PCV7) was included in the routine infant immunization schedule in Ireland in September 2008. We determined the serotype of 977 S. pneumoniae isolates causing invasive disease between 2000-2002 and 2007-2008, assessed for the presence of the recently described serotype 6C and determined the susceptibility of isolates during 2007-2008 to penicillin and cefotaxime. Serotype 14 was the most common serotype during both periods and 7·7% of isolates previously typed as serotype 6A were serotype 6C. During 2000-2002 and 2007-2008, PCV7 could potentially have prevented 85% and 74% of invasive pneumococcal disease in the target population (i.e. children aged <2 years), respectively. The level of penicillin non-susceptibility was 17% in 2007-2008. Ongoing surveillance of serotypes is required to determine the impact of PCV7 in the Irish population and to assess the potential of new vaccines with expanded valency.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Vickers I,Fitzgerald M,Murchan S,Cotter S,O'Flanagan D,Cafferkey M,Humphreys Hdoi
10.1017/S0950268810001743subject
Has Abstractpub_date
2011-05-01 00:00:00pages
783-90issue
5eissn
0950-2688issn
1469-4409pii
S0950268810001743journal_volume
139pub_type
杂志文章abstract::The 7-valent pneumococcal conjugate vaccine (PCV7) is reported to decrease the incidence of community-acquired pneumonia (CAP) in children. To determine the annual incidence of CAP before the introduction of PCV7, we counted the number of children hospitalized with CAP between 2008 and 2009 in Chiba City, Japan. We in...
journal_title:Epidemiology and infection
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abstract::The emergence of dengue haemorrhagic fever is a public health problem in Latin America and the Caribbean. This study, carried out in French Guiana where malaria is endemic, evaluated the value and the limitations of a non-specific alert system including all patients admitted to the emergency department of Cayenne Hosp...
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pub_type: 杂志文章,meta分析,评审
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journal_title:Epidemiology and infection
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更新日期:2012-10-01 00:00:00
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更新日期:2014-02-01 00:00:00
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