Attributing sporadic and outbreak-associated infections to sources: blending epidemiological data.

Abstract:

:Common sources of shiga toxin-producing Escherichia coli (STEC) O157 infection have been identified by investigating outbreaks and by case-control studies of sporadic infections. We conducted an analysis to attribute STEC O157 infections ascertained in 1996 and 1999 by the Foodborne Diseases Active Surveillance Network (FoodNet) to sources. Multivariable models from two case-control studies conducted in FoodNet and outbreak investigations that occurred during the study years were used to calculate the annual number of infections attributable to six sources. Using the results of the outbreak investigations alone, 27% and 15% of infections were attributed to a source in 1996 and 1999, respectively. Combining information from both data sources, 65% of infections in 1996 and 34% of infections in 1999 were attributed. The results suggest that methods to incorporate data from multiple surveillance systems and over several years are needed to improve estimation of the number of illnesses attributable to exposure sources.

journal_name

Epidemiol Infect

authors

Cole D,Griffin PM,Fullerton KE,Ayers T,Smith K,Ingram LA,Kissler B,Hoekstra RM

doi

10.1017/S0950268813000915

subject

Has Abstract

pub_date

2014-02-01 00:00:00

pages

295-302

issue

2

eissn

0950-2688

issn

1469-4409

pii

S0950268813000915

journal_volume

142

pub_type

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