Abstract:
:The minimum inhibitory concentration (MIC) of five antibiotics and the presence of resistance genes was determined in 163 Haemophilus influenzae isolates collected over 13 years (1987-2000) in four two-yearly sampling periods from patients with respiratory tract infections. The prevalence of beta-lactamase-negative ampicillin-susceptible strains was approximately 80% over the sampling period although fewer strains (65.9%) were recovered in the period 1995-1997. TEM-1 type beta-lactamase-producing strains were less frequent starting at 15.6% and declining to 2.2% in the final sampling period. Low-beta-lactamase-negative ampicillin-resistant (BLNAR) strains were uncommon in 1987-1989 (2.2%), peaked to 19.5% in 1995-1997, but fell back to 11.1% by 2000. Fully BLNAR strains were not detected until the last sampling period (6.7%). The MICs of ampicillin, levofloxacin, cefditoren and ceftriaxone remained stable but there was an eight-fold increase in the MIC of cefdinir over the sampling period. Pulsed-field gel electrophoresis of DNA digests showed that three representative BLNAR strains were genetically distinct and 11 DNA profiles were identified among 17 low-BLNAR strains. These data suggest that the number of genetically altered BLNAR and low-BLNAR strains are increasing in Japan.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Qin L,Watanabe H,Asoh N,Watanabe K,Oishi K,Mizota T,Nagatake Tdoi
10.1017/S0950268806007023subject
Has Abstractpub_date
2007-05-01 00:00:00pages
665-8issue
4eissn
0950-2688issn
1469-4409pii
S0950268806007023journal_volume
135pub_type
临床试验,杂志文章abstract::To determine the extent age, sex and co-infection affect morbidity in people infected with hepatitis C virus (HCV), we performed a population-based study linking HCV notifications in New South Wales, Australia with their hospital (July 2000 to June 2006), hepatitis B virus (HBV) and HIV notification, and death records...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S095026881000258X
更新日期:2011-08-01 00:00:00
abstract::Campylobacter jejuni serogroup reference strains and collections of sporadic and outbreak-associated isolates were examined for restriction fragment length polymorphisms (RFLPs), using C. jejuni random chromosomal and 16S rRNA gene probes. A collection of 48 Penner (HS) and 14 Lior (HL) serogroup reference strains, pl...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800001400
更新日期:1996-10-01 00:00:00
abstract::The prevalence of Escherichia coli O157 displays striking variability across the Scottish cattle population. On 78% of farms, in a cross-sectional survey of 952, no shedding of E. coli O157 was detected, but on a small proportion, approximately 2%, very high prevalences of infection were found (with 90-100% of pats sa...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268805004590
更新日期:2006-02-01 00:00:00
abstract::Experimental data suggest a role for the microflora in Systemic Lupus Erythematosus (SLE). Anti-ds-DNA antibodies may be pathogenic in SLE by forming immune complexes with DNA. Foreign bacteria in the intestines could constitute the stimulus for anti-ds-DNA antibody production in SLE. Colonization Resistance (CR) is t...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800057770
更新日期:1994-04-01 00:00:00
abstract::We used a structured population model to study factors determining the magnitude of indirect protection in Haemophilus influenzae type b (Hib) vaccination. On a simulation platform mimicking the population of Finland, a Hib transmission and immunity model, including cross-reactive bacterial encounters, was formulated....
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s095026880400250x
更新日期:2004-10-01 00:00:00
abstract::Nosocomial infection or colonization due to enterococci with high-level resistance to vancomycin (minimal inhibitory concentrations [MICs] between 64 and greater than 2000 mg/L) has occurred in 41 patients with renal disease. These vancomycin-resistant enterococci were cultured from many sources including blood. All b...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800030478
更新日期:1989-08-01 00:00:00
abstract::Computer models can be useful in planning interventions against novel strains of influenza. However such models sometimes make unsubstantiated assumptions about the relative infectivity of asymptomatic and symptomatic cases, or conversely assume there is no impact at all. Using household-level data from known-index st...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268816002740
更新日期:2017-03-01 00:00:00
abstract::Carrion is a major source of botulinal toxin for animals. A type D strain of Clostridium botulinum differed from type A and B strains in producing (1) much higher concentrations of toxin in putrefying mouse carcasses at several different temperatures over a period of 35 days, (2) toxicity that sometimes persisted in m...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800051761
更新日期:1994-10-01 00:00:00
abstract::Equine influenza virus (EIV) causes a highly contagious respiratory disease in equids, with confirmed outbreaks in Europe, America, North Africa, and Asia. Although China, Mongolia, and Japan have reported equine influenza outbreaks, Korea has not. Since 2011, we have conducted a routine surveillance programme to dete...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S095026881300143X
更新日期:2014-04-01 00:00:00
abstract::There is limited information on percent expenditure of household income due to childhood diarrhoea especially in rural Bangladesh. A total of 4205 children aged <5 years with acute diarrhoea were studied. Percent expenditure was calculated as total expenditure for the diarrhoeal episode divided by monthly family incom...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268814003781
更新日期:2015-10-01 00:00:00
abstract::Invasive group A streptococcal (GAS) disease is a condition of clinical and public health significance. We conducted epidemiological analyses to determine if the presence of gastrointestinal (GI) complaints (diarrhea and/or vomiting) early in the course of invasive GAS disease is associated with either of two severe o...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268809990938
更新日期:2010-04-01 00:00:00
abstract::A Q fever outbreak was declared in February 2016 in a company that manufactures hoists and chains and therefore with no apparent occupational-associated risk. Coxiella burnetii infection was diagnosed by serology in eight of the 29 workers of the company; seven of them had fever or flu-like signs and five had pneumoni...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268817000796
更新日期:2017-07-01 00:00:00
abstract::In a prospective observational study 4,485 patients from 46 clinical centres in 17 European countries were followed between April 1994 and November 1996. Information on AIDS-defining events (ADEs) were collected together with basic demographic data, treatment history and laboratory results. The centres were divided in...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268802007719
更新日期:2002-12-01 00:00:00
abstract::Cyclospora cayetanensis is an emerging infectious agent. The aim of this study was to describe an outbreak that occurred in 250 adults exposed to contaminated food, focusing on the duration and relapses of symptoms, complications and evidence of local transmission. This outbreak affected workers who ate in a restauran...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S095026881100121X
更新日期:2012-04-01 00:00:00
abstract::A growing number of infectious pathogens are spreading among geographic regions. Some pathogens that were previously not considered to pose a general threat to human health have emerged at regional and global scales, such as Zika and Ebola Virus Disease. Other pathogens, such as yellow fever virus, were previously tho...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268818002881
更新日期:2018-11-05 00:00:00
abstract::We report the molecular characterization of methicillin-resistant Staphylococcus aureus (MRSA) with resistance to tigecycline and to daptomycin isolated from intensive-care-unit patients in Brazil over a 6-month period. Thirty-six isolates (25 from infection sites, 11 from nasal sites) recovered from 23 patients who p...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268813001325
更新日期:2014-03-01 00:00:00
abstract::Despite being widely recognized as a significant public health problem there are surprisingly few contemporary data available on the incidence of pneumonia in the UK. We conducted a general population-based cohort study to determine the incidence of pneumonia in general practice in the United Kingdom. Data were obtain...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268808001428
更新日期:2009-05-01 00:00:00
abstract::Between January 1994 and October 1997, we interviewed 2576 black in-patients with newly diagnosed cancer in Johannesburg and Soweto, South Africa. Blood was tested for HIV-1 and HHV-8 antibodies and the study was restricted to 2191 HIV-1 antibody-negative patients. We examined the relationship between infection with H...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268804002845
更新日期:2004-12-01 00:00:00
abstract::In August 2015 a gastroenteritis outbreak occurred following a wedding. An outbreak investigation was undertaken and a cohort study was conducted using an online survey. Of 140 guests, 134 received the survey and 113 responded (84·3% response rate). Seventy respondents met the case definition of vomiting and/or diarrh...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268816003368
更新日期:2017-04-01 00:00:00
abstract::Targets for maximum acceptable levels of Salmonella in pigs and pork are to be decided. A stochastic simulation model accounting for herd and abattoir information was used to evaluate food safety and economic consequences of different surveillance and control strategies, based among others on Danish surveillance data....
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268810001767
更新日期:2011-05-01 00:00:00
abstract::In December 2008, three hospitalized cases of suspected psittacosis infection were notified by respiratory disease clinicians from a local hospital to the Regional Epidemiology Unit of Pays de la Loire, France. They all had attended a bird fair. A retrospective cohort study was conducted among exhibitors and organizer...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268811000409
更新日期:2011-10-01 00:00:00
abstract::This study compared the fatty-acid profiles of Brucella canis blood culture isolates obtained from infected dogs in the UK, Germany, Japan, South Africa, Peru, Mexico, Colombia, and Argentina, and from a human clinical case in Argentina, to a bank of isolates obtained from canine outbreaks in the USA. Analysis of a to...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268812001240
更新日期:2013-04-01 00:00:00
abstract::Medical records, for 2000 and 2001, of symptomatic amoebic patients who were treated at our hospitals in Tokyo, Yokohama and Osaka were studied retrospectively for the purpose of gathering epidemiological data on symptomatic Entamoeba histolytica infection. A total of 58 patients were treated. Fifty-five of them were ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268803001389
更新日期:2004-01-01 00:00:00
abstract::Two hundred and seventy-five consecutive clinical isolates of coagulase-negative staphylococci, including strains associated with disease, contaminants and skin colonizers, were speciated, tested for slime production and for their sensitivity to a range of antibiotics. Staphylococcus epidermidis was the most commonly ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800029265
更新日期:1988-08-01 00:00:00
abstract::We describe microbiological, clinical and epidemiological aspects of a diphtheria outbreak that occurred in Maranhão, Brazil. The majority of the 27 confirmed cases occurred in partially (n = 16) or completely (n = 10) immunized children (n = 26). Clinical signs and characteristic symptoms of diphtheria such as cervic...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268814001241
更新日期:2015-03-01 00:00:00
abstract::This paper compares strains of foot-and-mouth disease (FMD) serotype SAT (South African Territories) 2 viruses isolated from Zimbabwe and other African countries using monoclonal antibodies (MAb). A sandwich-ELISA was used to examine the relative binding of anti-SAT 2 MAb to the various viruses. The MAb-binding profil...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s095026880005826x
更新日期:1995-08-01 00:00:00
abstract::Due to human error, drinking water supplied to a new housing estate in The Netherlands was contaminated with grey water. The cohort of 921 accidentally exposed households (area A) had a higher attack rate for diarrhoea (54.1%) than a non-exposed cohort of 1529 households from an adjacent area (B) (24%) (RR 2.3, 95% CI...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268806007497
更新日期:2007-07-01 00:00:00
abstract::Varicella is a common and highly contagious childhood disease which impacts the public worldwide. Hong Kong children can only be vaccinated against the disease in private practice. The varicella vaccination rate of local children in preschool is uncertain. Therefore a cross-sectional kindergarten-based parent-administ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268813001994
更新日期:2014-05-01 00:00:00
abstract::Estimation of farm prevalence is common in veterinary research. Typically, not all animals within the farm are sampled, and imperfect tests are used. Often, assumptions about herd sizes and sampling proportions are made, which may be invalid in smallholder settings. We propose an alternative method for estimating farm...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268816001825
更新日期:2016-12-01 00:00:00
abstract::The clinical and microbiological characteristics of catheter-related bloodstream infection (CR-BSI) due to uncommon microorganisms was assessed in a retrospective case-control study over a 9-year period in a tertiary teaching hospital. Uncommon microorganisms were defined as those representing <0·5% of all CR-BSI. Dia...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268814001435
更新日期:2015-03-01 00:00:00