Species identification, antibiotic sensitivity and slime production of coagulase-negative staphylococci isolated from clinical specimens.

Abstract:

:Two hundred and seventy-five consecutive clinical isolates of coagulase-negative staphylococci, including strains associated with disease, contaminants and skin colonizers, were speciated, tested for slime production and for their sensitivity to a range of antibiotics. Staphylococcus epidermidis was the most commonly identified species, comprising 63% of all isolates. Slime production was detected in half the strains of Staph. epidermidis, Staph. haemolyticus and Staph. saprophyticus but was rare in other species. Most Staph. haemolyticus strains and approximately half of the Staph. epidermidis strains were resistant to five or more antibiotics. A significant association was found between slime production and multiple antibiotic resistance. For catheter-associated strains, clinical relevance was predictable by species i.e. Staph. epidermidis. Multi-resistant slime-positive Staph. haemolyticus strains, although infrequently associated with disease, were common skin colonizers, presumably acquired from the hospital environment. We describe a practical and inexpensive scheme for the speciation of human coagulase-negative staphylococcal isolates.

journal_name

Epidemiol Infect

authors

Deighton MA,Franklin JC,Spicer WJ,Balkau B

doi

10.1017/s0950268800029265

subject

Has Abstract

pub_date

1988-08-01 00:00:00

pages

99-113

issue

1

eissn

0950-2688

issn

1469-4409

journal_volume

101

pub_type

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