Abstract:
:Encephalitis is a clinical syndrome often associated with infectious agents. This study describes the epidemiology and disease burden associated with encephalitis in Canada and explores possible associations with arboviral causes. Encephalitis-associated hospitalizations, 1994-2008, were analysed according to aetiological category (based on ICD-9/ICD-10 codes) and other factors using multivariate logistic regression for grouped (blocked) data and negative binomial regression. A discrete Poisson model tested spatio-temporal clustering of hospitalizations associated with unclassified and arboviral encephalitis aetiologies. Encephalitis accounted for an estimated 24028 hospitalizations in Canada (5·2/100 000 population) and unknown aetiologies represented 50% of these hospitalizations. In 2003, clusters of unclassified encephalitis were identified in the summer and early autumn months signifying potential underlying arboviral aetiologies. Spatio-temporal patterns in encephalitis hospitalizations may help us to better understand the disease burden associated with arboviruses and other zoonotic pathogens in Canada and to develop appropriate surveillance systems.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Kulkarni MA,Lecocq AC,Artsob H,Drebot MA,Ogden NHdoi
10.1017/S095026881200252Xsubject
Has Abstractpub_date
2013-11-01 00:00:00pages
2243-55issue
11eissn
0950-2688issn
1469-4409pii
S095026881200252Xjournal_volume
141pub_type
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