Signs and symptoms in common colds.

Abstract:

:The patterns of disease caused by five common viruses which infect the respiratory tract are described. The viruses were strains of rhinovirus types 2, 9, and 14, a strain of coronavirus type 229E and of respiratory syncytial virus. Volunteers were given nasal drops containing a low infectious dose of one of the viruses, quarantined from 2 days before to 5 days after inoculation, and examined daily by a clinician using a standard checklist of respiratory signs and symptoms. Only subjects who developed clinical illness accompanied by viral shedding and/or specific antibody production were analysed [n = 116]. The results confirm indication from earlier studies that the main difference between colds induced by different viruses is in duration of the incubation period. Patterns of symptom development were not substantially different with different viruses. Analyses of signs and symptoms in different categories, e.g. nasal symptoms v. coughing, justify treatment with different drugs either successively or simultaneously.

journal_name

Epidemiol Infect

authors

Tyrrell DA,Cohen S,Schlarb JE

doi

10.1017/s0950268800056764

subject

Has Abstract

pub_date

1993-08-01 00:00:00

pages

143-56

issue

1

eissn

0950-2688

issn

1469-4409

journal_volume

111

pub_type

杂志文章
  • Usefulness of the DNA-fingerprinting pattern and the multilocus enzyme electrophoresis profile in the assessment of outbreaks of meningococcal disease.

    abstract::The objective of the study was to assess whether genotypic characterization by means of DNA-fingerprinting pattern (DFP) and multilocus enzyme electrophoresis (MEE) profile as compared to phenotypic characterization would improve the differentiation of Neisseria meningitidis strains associated with outbreaks from stra...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800052328

    authors: Weis N,Lind I

    更新日期:1996-04-01 00:00:00

  • Surveillance of listeriosis in the Tel Aviv District, Israel, 2010-2015.

    abstract::This study analyses the epidemiologic, clinical and molecular findings of all culture-confirmed cases of listeriosis notified from 2010 to 2015 in the Tel Aviv District, which is known to have high rates of listeriosis. All clinical isolates of Listeria monocytogenes were subtyped using two-enzyme pulsed-field gel ele...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268817003004

    authors: Salama M,Amitai Z,Ezernitchi AV,Sheffer R,Jaffe J,Rahmani S,Leshem E,Valinsky L

    更新日期:2018-02-01 00:00:00

  • Serotype distribution of Streptococcus pneumoniae causing invasive disease in the Republic of Ireland.

    abstract::The 7-valent pneumococcal conjugate vaccine (PCV7) was included in the routine infant immunization schedule in Ireland in September 2008. We determined the serotype of 977 S. pneumoniae isolates causing invasive disease between 2000-2002 and 2007-2008, assessed for the presence of the recently described serotype 6C an...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268810001743

    authors: Vickers I,Fitzgerald M,Murchan S,Cotter S,O'Flanagan D,Cafferkey M,Humphreys H

    更新日期:2011-05-01 00:00:00

  • Dynamics of Salmonella transmission on a British pig grower-finisher farm: a stochastic model.

    abstract::Previous modelling studies have estimated that between 1% and 10% of human salmonella infections are attributable to pig meat consumption. In response to this food safety threat the British pig industry have initiated a salmonella monitoring programme. It is anticipated that this programme will contribute to achieving...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268807008485

    authors: Hill AA,Snary EL,Arnold ME,Alban L,Cook AJ

    更新日期:2008-03-01 00:00:00

  • Time-course of antibody responses against Coxiella burnetii following acute Q fever.

    abstract::Large outbreaks of Q fever in The Netherlands have provided a unique opportunity for studying longitudinal serum antibody responses in patients. Results are presented of a cohort of 344 patients with acute symptoms of Q fever with three or more serum samples per patient. In all these serum samples IgM and IgG against ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268812000404

    authors: Teunis PF,Schimmer B,Notermans DW,Leenders AC,Wever PC,Kretzschmar ME,Schneeberger PM

    更新日期:2013-01-01 00:00:00

  • A re-evaluation of the impact of temperature and climate change on foodborne illness.

    abstract::The effects of temperature on reported cases of a number of foodborne illnesses in England and Wales were investigated. We also explored whether the impact of temperature had changed over time. Food poisoning, campylobacteriosis, salmonellosis, Salmonella Typhimurium infections and Salmonella Enteritidis infections we...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268809002477

    authors: Lake IR,Gillespie IA,Bentham G,Nichols GL,Lane C,Adak GK,Threlfall EJ

    更新日期:2009-11-01 00:00:00

  • Time to Rt < 1 for COVID-19 public health lockdown measures.

    abstract::The epidemiological target of lockdowns is to drive down the effective reproduction number (Rt) to less than 1. A key unknown is the duration that lockdowns need to be in place to achieve this and which lockdown measures are effective. Daily number of laboratory confirmed community coronavirus 2019 cases were extracte...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268820002964

    authors: Yung CF,Saffari E,Liew C

    更新日期:2020-12-09 00:00:00

  • Assessing the impact of a nurse-delivered home dried blood spot service on uptake of testing for household contacts of hepatitis B-infected pregnant women across two London trusts.

    abstract::Despite national guidance recommending testing and vaccination of household contacts of hepatitis B-infected pregnant women, provision and uptake of this is sub-optimal. The aim of this study was to evaluate the use of in-home dried blood spot (DBS) testing to increase testing and vaccination of household contacts of ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268815003325

    authors: Keel P,Edwards G,Flood J,Nixon G,Beebeejaun K,Shute J,Poh J,Millar A,Ijaz S,Parry J,Mandal S,Ramsay M,Amirthalingam G

    更新日期:2016-07-01 00:00:00

  • Study of colonization resistance for Enterobacteriaceae in man by experimental contamination and biotyping as well as the possible role of antibodies in the clearance of these bacteria from the intestines.

    abstract::The colonization resistance (CR) of the digestive tract was determined in 10 healthy volunteers by oral contamination with a neomycin resistant Escherichia coli (NR-E. coli) strain and measurement of the faecal concentration of this strain during 14 days after the contamination. This 'gold standard' was compared with ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800049311

    authors: Apperloo-Renkema HZ,van der Waaij D

    更新日期:1991-12-01 00:00:00

  • Temporally distinct Escherichia coli 0157 outbreaks associated with alfalfa sprouts linked to a common seed source--Colorado and Minnesota, 2003.

    abstract::Escherichia coli O157 outbreaks were identified in Minnesota in February 2003 involving seven persons and in Colorado in July 2003 involving 13 persons. Case isolates from the two states had matching pulsed-field gel electrophoresis (PFGE) patterns. Independent case-control studies linked infections in each outbreak w...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268804003589

    authors: Ferguson DD,Scheftel J,Cronquist A,Smith K,Woo-Ming A,Anderson E,Knutsen J,De AK,Gershman K

    更新日期:2005-06-01 00:00:00

  • The prevalence and genetics of resistance to commonly used antimicrobial agents in faecal Enterobacteriaceae from children in Bangladesh.

    abstract::The present study was undertaken to investigate the occurrence of antibiotic resistance in enteric flora in 64 children in rural Bangladesh over a 12-month period. The antibiotic resistance pattern of the isolates varied throughout the year and multiple resistance was highest during the post monsoon period. Seventy-th...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800050871

    authors: Mamun KZ,Shears P,Hart CA

    更新日期:1993-06-01 00:00:00

  • Determining the ideal prevention strategy for multidrug-resistance organisms in resource-limited countries: a cost-effectiveness analysis study.

    abstract::The aim of this study was to determine the most cost-effective strategy for the prevention and control of multidrug-resistant organisms (MDROs) in intensive care units (ICUs) in areas with limited health resources. The study was conducted in 12 ICUs of four hospitals. The total cost for the prevention of MDROs and the...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268820001120

    authors: Wang Y,Yuan Y,Lin L,Tan X,Tan Y

    更新日期:2020-05-20 00:00:00

  • Healthcare utilization and lost productivity due to infectious gastroenteritis, results from a national cross-sectional survey Australia 2008-2009.

    abstract::The aim of this study was to estimate the healthcare usage and loss of productivity due to gastroenteritis in Australia using the National Gastroenteritis Survey II. In 2008-2009, 7578 participants across Australia were surveyed about infectious gastroenteritis by telephone interview. A gastroenteritis case was define...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268815001375

    authors: Chen Y,Ford L,Hall G,Dobbins T,Kirk M

    更新日期:2016-01-01 00:00:00

  • Estimating infectious diseases incidence: validity of capture-recapture analysis and truncated models for incomplete count data.

    abstract::Capture-recapture analysis has been used to evaluate infectious disease surveillance. Violation of the underlying assumptions can jeopardize the validity of the capture-recapture estimates and a tool is needed for cross-validation. We re-examined 19 datasets of log-linear model capture-recapture studies on infectious ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268807008254

    authors: van Hest NA,Grant AD,Smit F,Story A,Richardus JH

    更新日期:2008-01-01 00:00:00

  • Effect of climatological factors on respiratory syncytial virus epidemics.

    abstract::Respiratory syncytial virus (RSV) presents as yearly epidemics in temperate climates. We analysed the association of atmospheric conditions to RSV epidemics in San Luis Potosí, S.L.P., Mexico. The weekly number of RSV detections from October 2002 and May 2006 were correlated to ambient temperature, barometric pressure...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268807000143

    authors: Noyola DE,Mandeville PB

    更新日期:2008-10-01 00:00:00

  • Assessing the risk from emerging infections.

    abstract::Emerging infections pose a constant threat to society and can require a substantial response, thus systems to assess the threat level and inform prioritization of resources are essential. A systematic approach to assessing the risk from emerging infections to public health in the UK has been developed. This qualitativ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,评审

    doi:10.1017/S0950268809990227

    authors: Morgan D,Kirkbride H,Hewitt K,Said B,Walsh AL

    更新日期:2009-11-01 00:00:00

  • A secondary school outbreak of mumps following the childhood immunization programme in England and Wales.

    abstract::Since the introduction of routine measles, mumps and rubella immunization for children in England and Wales in 1988, the incidence of mumps has declined steadily. We describe an outbreak of mumps in 1996 attacking 34 of a cohort of 98 schoolchildren born in 1982 and 1983. This is the largest outbreak in the UK since t...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s095026889900343x

    authors: Wehner H,Morris R,Logan M,Hunt D,Jin L,Stuart J,Cartwright K

    更新日期:2000-02-01 00:00:00

  • Assessment of areas at increased risk for poliovirus circulation in Ecuador.

    abstract::To assess areas at risk for poliovirus circulation in Ecuador, we first selected provinces at highest risk based on low immunization coverage with three doses of oral poliovirus vaccine, and a low number of reported cases of acute flaccid paralysis (AFP). Subsequently, we reviewed discharge data for the period 1996--2...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,多中心研究

    doi:10.1017/s0950268804002626

    authors: Dayan GH,Rodríguez R,Vinjé J,Vásconez N,Cáceres V,Gregoricus N,Sobsey M,Landaverde M

    更新日期:2004-10-01 00:00:00

  • Multistate product traceforward investigation to link imported romaine lettuce to a US cyclosporiasis outbreak - Nebraska, Texas, and Florida, June-August 2013.

    abstract::During June-August 2013, 25 US states reported 631 cyclosporiasis cases including Nebraska and Iowa where a regional investigation implicated common-source imported salad mix served in two chain restaurants. At least two common-origin growing fields were likely sources of contaminated romaine lettuce. Using producer- ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268815002320

    authors: Buss BF,Joshi MV,Dement JL,Cantu V,Safranek TJ

    更新日期:2016-10-01 00:00:00

  • Molecular variation of meningococcal serotype 4 antigen genes.

    abstract::Changes in the frequency of serogroup B non serotypable (B:NT) meningococci isolated in England and Wales were investigated by T-track fingerprint analysis, DNA nucleotide sequence determination, and serotyping by whole cell ELISA and dot blot assay. Seventy-three per cent of the isolates designated as B:NT by the Men...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268898008942

    authors: Urwin R,Feavers IM,Jones DM,Maiden MC,Fox AJ

    更新日期:1998-08-01 00:00:00

  • An epidemic of sporotrichosis in Rio de Janeiro, Brazil: epidemiological aspects of a series of cases.

    abstract::The first epidemic of sporotrichosis in humans as a result of zoonotic transmission was identified in Rio de Janeiro, Brazil, in 1998. A cross-sectional study was conducted applying questionnaires to patients seen in 2002 at Evandro Chagas Clinical Research Institute, Fiocruz, with a confirmed diagnosis of sporotricho...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268807009727

    authors: Barros MB,Schubach AO,Schubach TM,Wanke B,Lambert-Passos SR

    更新日期:2008-09-01 00:00:00

  • Vaccine prophylaxis of abattoir-associated Q fever: eight years' experience in Australian abattoirs.

    abstract::During the period 1981-8 a clinical trial of a Q fever vaccine (Q-vax; Commonwealth Serum Laboratories, Melbourne) has been conducted in abattoir workers and other at-risk groups in South Australia. Volunteers in four abattoirs and visitors to the abattoirs were given one subcutaneous dose of 30 micrograms of a formal...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800059458

    authors: Marmion BP,Ormsbee RA,Kyrkou M,Wright J,Worswick DA,Izzo AA,Esterman A,Feery B,Shapiro RA

    更新日期:1990-04-01 00:00:00

  • Isolation measures and protection awareness are significant for latent tuberculosis infection: a cross-sectional study based on T-SPOT.TB among health care workers in China.

    abstract::This study aimed to reveal the associated risk factors for latent tuberculosis infection (LTBI) detected by T-SPOT.TB assay among health care workers (HCWs) at different working locations or job categories in China. This cross-sectional study included 934 HCWs who underwent the T-SPOT.TB assay. Demographic and social ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268818002777

    authors: Deng Y,Liu Y,Li Y,Jing H,Wang Y,Li X,Xu L

    更新日期:2019-01-01 00:00:00

  • The study of infectious intestinal disease in England: socio-economic impact.

    abstract::To assess the socio-economic impact of infectious intestinal disease (IID) on the health care sector, cases and their families, cases of IID ascertained from a population cohort component and those presenting to general practices were sent a socio-economic questionnaire 3 weeks after the acute episode. The impact of t...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268802007690

    authors: Roberts JA,Cumberland P,Sockett PN,Wheeler J,Rodrigues LC,Sethi D,Roderick PJ,Infectious Intestinal Disease Study Executive.

    更新日期:2003-02-01 00:00:00

  • Skin and soft-tissue infection caused by non-tuberculous mycobacteria in Taiwan, 1997-2008.

    abstract::The aim of this study was to investigate the clinical, microbiological, and pathological characteristics and the outcomes of skin and soft-tissue infection (SSTI) caused by non-tuberculous mycobacteria (NTM). Medical records of 50 patients with SSTI caused by NTM identified from 2005 to 2008 and 63 patients previously...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268810001603

    authors: Chen HY,Chen CY,Huang CT,Ruan SY,Chou CH,Lai CC,Liao CH,Tan CK,Huang YT,Yu CJ,Hsueh PR

    更新日期:2011-01-01 00:00:00

  • Regional and temporal changes in AIDS in Europe before HAART.

    abstract::In a prospective observational study 4,485 patients from 46 clinical centres in 17 European countries were followed between April 1994 and November 1996. Information on AIDS-defining events (ADEs) were collected together with basic demographic data, treatment history and laboratory results. The centres were divided in...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268802007719

    authors: Blaxhult A,Fox Z,Colebunders R,Francioli P,Ben-Ishai Z,Fätkenheuer G,Parkin JM,Vanhems P,Phillips AN,Kirk O,EuroSIDA Study Group.

    更新日期:2002-12-01 00:00:00

  • Prospective study of the incidence of diarrhoea and prevalence of bacterial pathogens in a cohort of Vietnamese children along the Red River.

    abstract::We prospectively studied diarrhoea incidence among 1655 children < 5 years of age in northern Vietnam for 1 year using primarily passive surveillance. Standard culture methods were used to detect bacterial pathogens. Overall 2160 cases occurred (13 cases/child per year). Peak rates of diarrhoea occurred in children < ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268801005933

    authors: Isenbarger DW,Hien BT,Ha HT,Ha TT,Bodhidatta L,Pang LW,Cam PD

    更新日期:2001-10-01 00:00:00

  • Combined tests with Xpert MTB/RIF assay with bronchoalveolar lavage fluid increasing the diagnostic performance of smear-negative pulmonary tuberculosis in Eastern China.

    abstract::Tuberculosis (TB) remains a global public health threat. Misdiagnosis and delayed therapy of sputum smear-negative TB can affect the treatment outcomes and promote pathogen transmission. The application of Xpert MTB/RIF assay in bronchoalveolar lavage fluid (BALF) has been recommended but needs clinical evidence. We c...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026882000309X

    authors: Liu Q,Ji Y,Martinez L,Lu W,Shi X,Wang J,Zeng Y

    更新日期:2020-12-28 00:00:00

  • Changing epidemiology of cholera due to Vibrio cholerae O1 and O139 Bengal in Dhaka, Bangladesh.

    abstract::At the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR, B) Dhaka we studied the trends in cholera for the period January 1992 to May 1995. Vibrio cholerae O139 Bengal emerged as a second aetiologic agent of cholera in Dhaka in January 1993. In 1993, the majority of cholera cases was due to V. c...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800052572

    authors: Faruque AS,Fuchs GJ,Albert MJ

    更新日期:1996-06-01 00:00:00

  • Emergence of increasing linezolid-resistance in enterococci in a post-outbreak situation with vancomycin-resistant Enterococcus faecium.

    abstract::During 2004 and at the start of 2005 a university hospital in Southwest Germany was affected by an extensive outbreak of vancomycin-resistant Enterococcus faecium (VRE). Although the outbreak was contained, linezolid-resistant enterococci emerged during and after the outbreak as the usage of linezolid became more comm...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268807009508

    authors: Schulte B,Heininger A,Autenrieth IB,Wolz C

    更新日期:2008-08-01 00:00:00