Epidemiological and laboratory investigations of outbreaks of diarrhoea in rural South India: implications for control of disease.

Abstract:

:Two epidemics of acute, watery diarrhoea in villages in North Arcot district, India, were investigated. The attack rates were 10.03 and 15.53 per 100 population, the median duration was 5 days and enteric pathogens were present in 56.8% and 60.3% of specimens from the two villages, but no predominant pathogen was identified. Examination of stools from a 20% age-stratified random sample of the population of one of the villages after the epidemic found 22.9% of asymptomatic subjects excreted bacterial enteric pathogens. Despite the high background of enteric pathogen carriage, the isolation rates for shigellae, enteropathogenic Escherichia coli and Shiga-toxin producing E. coli were significantly higher (P < 0.001, P < 0.02, P < 0.05) during the epidemic. The epidemics may have been caused by faecal contamination of well water following rain. Point-of-use techniques for water disinfection may be most effective for preventing such outbreaks, but further research into the development of appropriate technology is required.

journal_name

Epidemiol Infect

authors

Kang G,Ramakrishna BS,Daniel J,Mathan M,Mathan VI

doi

10.1017/s0950268801005799

subject

Has Abstract

pub_date

2001-08-01 00:00:00

pages

107-12

issue

1

eissn

0950-2688

issn

1469-4409

journal_volume

127

pub_type

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