Abstract:
:Salmonella is a frequent cause of foodborne illness. However, since most symptomatic cases are not diagnosed, the true infection pressure is unknown. Furthermore, national surveillance systems have different sensitivities that limit inter-country comparisons. We have used recently developed methods for translating measurements of Salmonella antibodies into estimates of seroincidence: the frequency of infections including asymptomatic cases. This methodology was applied to cross-sectional collections of serum samples obtained from the general healthy population in three European countries. Denmark and The Netherlands had the lowest seroincidence (84,169 infections/1000 person-years), whereas Poland had the highest seroincidence (547/1000 person-years). A Bayesian method for obtaining incidence rate ratios was developed; this showed a 6·3 (95% credibility interval 3·3-12·5) higher incidence in Poland than in Denmark which demonstrates that this methodology has a wider applicability for studies of surveillance systems and evaluation of control programmes.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Simonsen J,Teunis P,van Pelt W,van Duynhoven Y,Krogfelt KA,Sadkowska-Todys M,Mølbak Kdoi
10.1017/S0950268810000750subject
Has Abstractpub_date
2011-04-01 00:00:00pages
636-43issue
4eissn
0950-2688issn
1469-4409pii
S0950268810000750journal_volume
139pub_type
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