Barrow-in-Furness: a large community legionellosis outbreak in the UK.

Abstract:

:A community outbreak of legionellosis occurred in Barrow-in-Furness, Cumbria, during July and August 2002. A descriptive study and active case-finding were instigated and all known wet cooling systems and other potential sources were investigated. Genotypic and phenotypic analysis, and amplified fragment length polymorphism of clinical human and environmental isolates confirmed the air-conditioning unit of a council-owned arts and leisure centre to be the source of infection. Subsequent sequence-based typing confirmed this link. One hundred and seventy-nine cases, including seven deaths [case fatality rate (CFR) 3·9%] were attributed to the outbreak. Timely recognition and management of the incident very likely led to the low CFR compared to other outbreaks. The outbreak highlights the responsibility associated with managing an aerosol-producing system, with the potential to expose and infect a large proportion of the local population and the consequent legal ramifications and human cost.

journal_name

Epidemiol Infect

authors

Bennett E,Ashton M,Calvert N,Chaloner J,Cheesbrough J,Egan J,Farrell I,Hall I,Harrison TG,Naik FC,Partridge S,Syed Q,Gent RN

doi

10.1017/S0950268813002483

subject

Has Abstract

pub_date

2014-08-01 00:00:00

pages

1763-77

issue

8

eissn

0950-2688

issn

1469-4409

pii

S0950268813002483

journal_volume

142

pub_type

杂志文章
  • The seroepidemiology of B. pertussis infection in Catalonia, Spain.

    abstract::A survey of the seroprevalence of pertussis antibodies in a representative sample of the population from Catalonia was carried out. Ninety-seven municipalities and 30 schools were randomly selected to recruit the 2126 subjects who participated in the study. A serum sample was obtained from all individuals participatin...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268801005325

    authors: Domínguez A,Vidal J,Plans P,Salleras L

    更新日期:2001-04-01 00:00:00

  • Distribution of Escherichia coli strains harbouring Shiga toxin-producing E. coli (STEC)-associated virulence factors (stx1, stx2, eae, ehxA) from very young calves in the North Island of New Zealand.

    abstract::The objective of this study was to determine the distribution of Shiga toxin-producing Escherichia coli (STEC) virulence markers (stx1, stx2, eae, ehxA) in E. coli strains isolated from young calves aged fewer than 7 days (bobby calves). In total, 299 recto-anal mucosal swabs were collected from animals at two slaught...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814000089

    authors: Irshad H,Cookson AL,Prattley DJ,Dufour M,French NP

    更新日期:2014-12-01 00:00:00

  • Characteristics and TB treatment outcomes in TB patients with viral hepatitis, New York City, 2000-2010.

    abstract::Literature surrounding the burden of and factors associated with hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in persons with tuberculosis (TB) disease remains limited and focused on populations outside the USA. Cross-matched New York City (NYC) TB and viral hepatitis surveillance data were used to es...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814002970

    authors: Bushnell G,Stennis NL,Drobnik AM,Proops DC,Ahuja SD,Bornschlegel K,Fuld J

    更新日期:2015-07-01 00:00:00

  • Existence of two geographically-linked clonal lineages in the bacterial fish pathogen Photobacterium damselae subsp. piscicida evidenced by random amplified polymorphic DNA analysis.

    abstract::In this work, we applied the random amplified polymorphic DNA (RAPD) technique to evaluate the genetic diversity in Photobacterium damselae subsp. piscicida (formerly Pasteurella piscicida), an important pathogen for different marine fish. Regardless of the oligonucleotide primer employed, the 29 isolates of Ph. damse...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268899004252

    authors: Magariños B,Toranzo AE,Barja JL,Romalde JL

    更新日期:2000-08-01 00:00:00

  • Contribution of Meat Inspection to the surveillance of poultry health and welfare in the European Union.

    abstract::In the European Union, Meat Inspection (MI) aims to protect public health by ensuring that minimal hazardous material enters in the food chain. It also contributes to the detection and monitoring of animal diseases and welfare problems but its utility for animal surveillance has been assessed partially for some diseas...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814003379

    authors: Huneau-Salaün A,Stärk KD,Mateus A,Lupo C,Lindberg A,LE Bouquin-Leneveu S

    更新日期:2015-08-01 00:00:00

  • Experimental studies on the comparative infectivity and pathogenicity of Streptococcus suis type 2. I. Porcine and human isolates in pigs.

    abstract::Piglets between 1 and 40 days of age were inoculated with varying numbers and with different isolates of Streptococcus suis type 2 by the intranasal, intravenous and subarachnoid routes. Less than 100 organisms of an isolate cultured from apparently normal pigs caused subclinical infection in 1-day-old piglets after i...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800048081

    authors: Robertson ID,Blackmore DK

    更新日期:1990-12-01 00:00:00

  • The effect of vaccination on undetected persistence of foot-and-mouth disease virus in cattle herds and sheep flocks.

    abstract::The importance of carrier animals (those in whom virus persists after recovery from disease or acute infection) and their potential role in the spread of disease remain open questions within foot-and-mouth disease epidemiology. Using simple probabilistic models we attempt to quantify the effect of emergency vaccinatio...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268809002349

    authors: Schley D,Paton DJ,Cox SJ,Parida S,Gubbins S

    更新日期:2009-10-01 00:00:00

  • Concurrent outbreaks with co-infection of norovirus and Clostridium difficile in a long-term-care facility.

    abstract::We describe an outbreak of simultaneous Clostridium difficile and norovirus infections in a long-term-care facility. Thirty patients experienced acute gastroenteritis, and four had co-infection with identical C. difficile 027 and genotype II.4 New Orleans norovirus strains. Co-occurring infection requires improved und...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268813000241

    authors: Ludwig A,Sato K,Schirmer P,Maniar A,Lucero-Obusan C,Fleming C,Ryono R,Oda G,Winters M,Holodniy M

    更新日期:2013-08-01 00:00:00

  • Seroprevalence, correlates and trends of Helicobacter pylori infection in the Israeli population.

    abstract::We examined the prevalence, correlates and trends of H. pylori infection in Israel using residual sera obtained in 2007-2008 from 1466 Jewish subjects aged 0-77 years and 897 Arabs aged 0-19 years, and in 2000-2001 from 627 Jewish and 575 Arab subjects aged 0-19 years. H. pylori IgG antibodies were measured by ELISA. ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268811002081

    authors: Muhsen K,Cohen D,Spungin-Bialik A,Shohat T

    更新日期:2012-07-01 00:00:00

  • An outbreak of Trichinella spiralis infection in southern Lebanon.

    abstract::An outbreak of trichinosis occurred during January 1995 in a south Lebanese village with a population of 800-1000 persons. The estimated number of persons treated for a Trichinella-like illness was 200. Sixty-three persons sought medical attention at a local infirmary: 44 of them were diagnosed as having trichinosis o...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268897007875

    authors: Haim M,Efrat M,Wilson M,Schantz PM,Cohen D,Shemer J

    更新日期:1997-12-01 00:00:00

  • Louse-borne relapsing fever (Borrelia recurrentis infection).

    abstract::Louse-borne relapsing fever (LBRF) is an epidemic disease with a fascinating history from Hippocrates' times, through the 6th century 'Yellow Plague', to epidemics in Ireland, Scotland and England in the 19th century and two large Afro-Middle Eastern pandemics in the 20th century. An endemic focus persists in Ethiopia...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,评审

    doi:10.1017/S0950268819000116

    authors: Warrell DA

    更新日期:2019-01-01 00:00:00

  • Time to Rt < 1 for COVID-19 public health lockdown measures.

    abstract::The epidemiological target of lockdowns is to drive down the effective reproduction number (Rt) to less than 1. A key unknown is the duration that lockdowns need to be in place to achieve this and which lockdown measures are effective. Daily number of laboratory confirmed community coronavirus 2019 cases were extracte...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268820002964

    authors: Yung CF,Saffari E,Liew C

    更新日期:2020-12-09 00:00:00

  • Is hand, foot and mouth disease associated with meteorological parameters?

    abstract::We examined the relationship between meteorological parameters and hand, foot and mouth disease (HFMD) activity. Meteorological data collected from 2000 to 2004 were tested for correlation with HFMD consultation rates calculated through the sentinel surveillance system in Hong Kong. The regression model constructed wa...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268810002256

    authors: Ma E,Lam T,Wong C,Chuang SK

    更新日期:2010-12-01 00:00:00

  • Assessing the impact of a nurse-delivered home dried blood spot service on uptake of testing for household contacts of hepatitis B-infected pregnant women across two London trusts.

    abstract::Despite national guidance recommending testing and vaccination of household contacts of hepatitis B-infected pregnant women, provision and uptake of this is sub-optimal. The aim of this study was to evaluate the use of in-home dried blood spot (DBS) testing to increase testing and vaccination of household contacts of ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268815003325

    authors: Keel P,Edwards G,Flood J,Nixon G,Beebeejaun K,Shute J,Poh J,Millar A,Ijaz S,Parry J,Mandal S,Ramsay M,Amirthalingam G

    更新日期:2016-07-01 00:00:00

  • The importance of distinguishing COVID-19 from more common respiratory illnesses.

    abstract::We recruited 1591 patients who presented to our fever clinics from 23 January 2020 to 16 February 2020. The different imaging findings between COVID-19 pneumonia and influenza A viruses, influenza B virus pneumonia were also investigated. Most patients were infected by influenza A and B viruses in the flu-season. A la...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268820001971

    authors: Zhao W,Xie X,Liu J

    更新日期:2020-09-02 00:00:00

  • The human pathogenic vibrios--a public health update with environmental perspectives.

    abstract::Pathogenic Vibrio species are naturally-occurring bacteria in freshwater and saline aquatic environments. Counts of free-living bacteria in water are generally less than required to induce disease. Increases in number of organisms towards an infective dose can occur as water temperatures rise seasonally followed by gr...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,评审

    doi:10.1017/s0950268800030326

    authors: West PA

    更新日期:1989-08-01 00:00:00

  • Seasonal patterns in time series of pertussis.

    abstract::To gain insight into pertussis disease dynamics, we studied age-specific long-term periodicity and seasonality of pertussis in The Netherlands. Hierarchical time-series models were used to analyse the monthly reported pertussis incidence in January 1996-June 2006 by age group. The incidence of pertussis showed a sligh...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268809002489

    authors: De Greeff SC,Dekkers AL,Teunis P,Rahamat-Langendoen JC,Mooi FR,De Melker HE

    更新日期:2009-10-01 00:00:00

  • A longitudinal household study of Streptococcus pneumoniae nasopharyngeal carriage in a UK setting.

    abstract::A 10-month longitudinal household study of pre-school children and their families was undertaken with monthly visits collecting epidemiological data and nasopharyngeal swabs in Hertfordshire, England from 2001 to 2002. Pneumococcal culture was with standard methods. In total, 121 families (489 individuals) took part. ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268805004012

    authors: Hussain M,Melegaro A,Pebody RG,George R,Edmunds WJ,Talukdar R,Martin SA,Efstratiou A,Miller E

    更新日期:2005-10-01 00:00:00

  • The incidence of varicella and herpes zoster in Taiwan during a period of increasing varicella vaccine coverage, 2000-2008.

    abstract::The introduction and the widespread use of the varicella vaccine in Taiwan has led to a 75-80% decrease in the incidence of varicella in children. However the vaccine's long-term impact on the incidence of herpes zoster (HZ) has attracted attention. By controlling gender, underlying diseases, and age effects, a Poisso...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268811001786

    authors: Chao DY,Chien YZ,Yeh YP,Hsu PS,Lian IB

    更新日期:2012-06-01 00:00:00

  • Assessment of areas at increased risk for poliovirus circulation in Ecuador.

    abstract::To assess areas at risk for poliovirus circulation in Ecuador, we first selected provinces at highest risk based on low immunization coverage with three doses of oral poliovirus vaccine, and a low number of reported cases of acute flaccid paralysis (AFP). Subsequently, we reviewed discharge data for the period 1996--2...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,多中心研究

    doi:10.1017/s0950268804002626

    authors: Dayan GH,Rodríguez R,Vinjé J,Vásconez N,Cáceres V,Gregoricus N,Sobsey M,Landaverde M

    更新日期:2004-10-01 00:00:00

  • Prevalence of and risk factors for MRSA carriage in companion animals: a survey of dogs, cats and horses.

    abstract::We investigated the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) carriage in a convenience sample of purposely selected populations of dogs, cats and horses in the Greater London area. Swabs from carriage sites were pooled, enriched and processed by standard bacteriological methods. The presence of...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026881000227X

    authors: Loeffler A,Pfeiffer DU,Lindsay JA,Soares Magalhães RJ,Lloyd DH

    更新日期:2011-07-01 00:00:00

  • Mixed viral infections causing acute gastroenteritis in children in a waterborne outbreak.

    abstract::We examined stool specimens for viral pathogens from 50 children referred to hospital due to acute gastroenteritis (AGE) resulting from consuming drinking water contaminated with sewage in a Finnish community using PCR methods. Rotavirus was detected in 33 (66%), human calicivirus in 31 (62%), and both in 40% of cases...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268809991671

    authors: Räsänen S,Lappalainen S,Kaikkonen S,Hämäläinen M,Salminen M,Vesikari T

    更新日期:2010-09-01 00:00:00

  • Association between Toxoplasma gondii exposure and paediatrics haematological malignancies: a case-control study.

    abstract::The possible association between Toxoplasma gondii infection and paediatric haematological malignancies in a group of patients and control subjects was evaluated in the present study. We performed an age-, gender- and residence frequency-matched case-control study of 101 blood cancer patients under 18 years of age, al...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268818002194

    authors: Kalantari N,Rezanejad J,Tamadoni A,Ghaffari S,Alipour J,Bayani M

    更新日期:2018-11-01 00:00:00

  • Outbreaks of Escherichia coli O157 infections at multiple county agricultural fairs: a hazard of mixing cattle, concession stands and children.

    abstract::Escherichia coli O157 infections cause an estimated 60 deaths and 73 000 illnesses annually in the United States. A marked summer peak in incidence is largely unexplained. We investigated an outbreak of E. coli O157 infections at an agricultural fair in Ohio and implicated consumption of beverages made with fairground...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268803001237

    authors: Crump JA,Braden CR,Dey ME,Hoekstra RM,Rickelman-Apisa JM,Baldwin DA,De Fijter SJ,Nowicki SF,Koch EM,Bannerman TL,Smith FW,Sarisky JP,Hochberg N,Mead PS

    更新日期:2003-12-01 00:00:00

  • An outbreak of Legionnaires' disease in Gloucester.

    abstract::Fourteen people living in or near the city of Gloucester fell ill with Legionnaires' disease caused by Legionella pneumophila serogroup (SG) 1 between 27 August and 27 October 1986. Another patient had fallen ill on 30 May. Nine of the 15 were diagnosed retrospectively during a case finding exercise. There were three ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800048767

    authors: Hunt DA,Cartwright KA,Smith MC,Middleton J,Bartlett CL,Lee JV,Dennis PJ,Harper D

    更新日期:1991-08-01 00:00:00

  • Applications of machine learning techniques to predict filariasis using socio-economic factors.

    abstract::Filariasis is one of the major public health concerns in India. Approximately 600 million people spread across 250 districts of India are at risk of filariasis. To predict this disease, a pilot scale study was carried out in 30 villages of Karimnagar district of Telangana from 2004 to 2007 to collect epidemiological a...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268819001481

    authors: Kondeti PK,Ravi K,Mutheneni SR,Kadiri MR,Kumaraswamy S,Vadlamani R,Upadhyayula SM

    更新日期:2019-09-02 00:00:00

  • Quantifying homologous and heterologous antibody titre rises after influenza virus infection.

    abstract::Most influenza virus infections are associated with mild disease. One approach to estimate the occurrence of influenza virus infections in individuals is via repeated measurement of humoral antibody titres. We used baseline and convalescent antibody titres measured by haemagglutination inhibition (HI) and viral neutra...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268816000583

    authors: Freeman G,Perera RA,Ngan E,Fang VJ,Cauchemez S,Ip DK,Peiris JS,Cowling BJ

    更新日期:2016-08-01 00:00:00

  • Deviating from IDSA treatment guidelines for non-purulent skin infections increases the risk of treatment failure in emergency department patients.

    abstract::The Infectious Disease Society of America (IDSA) publishes guidelines regularly for the management of skin and soft tissue infections; however, the extent to which practice patterns follow these guidelines and if this can affect treatment failure rates is unknown. We observed the treatment failure rates from a multice...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268818003291

    authors: Haran JP,Wilsterman E,Zeoli T,Goulding M,McLendon E,Clark MA

    更新日期:2018-12-05 00:00:00

  • A community outbreak of Campylobacter jejuni infection from a chlorinated public water supply.

    abstract::An outbreak of Campylobacter jejuni infection occurred in a South Wales Valleys housing estate. Illness in estate residents was associated with tap water consumption [population attributable risk (PAR) 50%, relative risk (RR) 2.53, 95% confidence interval (CI) 1.9-3.37] and residence in the upper estate (PAR 49%, RR 2...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268807007960

    authors: Richardson G,Thomas DR,Smith RM,Nehaul L,Ribeiro CD,Brown AG,Salmon RL

    更新日期:2007-10-01 00:00:00

  • Prevalence of antibodies to Brucella spp. in cattle, sheep, goats, horses and camels in the State of Eritrea; influence of husbandry systems.

    abstract::Samples from 2427 cattle, 661 goats, 104 sheep, 98 camels and 82 horses were screened for brucella infections by the Rose Bengal Test and positive reactors confirmed by the complement fixation test. In cattle, the highest individual seroprevalence was in dairy herds kept under the intensive husbandry system, with an i...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268899004501

    authors: Omer MK,Skjerve E,Holstad G,Woldehiwet Z,Macmillan AP

    更新日期:2000-10-01 00:00:00