Quantifying homologous and heterologous antibody titre rises after influenza virus infection.

Abstract:

:Most influenza virus infections are associated with mild disease. One approach to estimate the occurrence of influenza virus infections in individuals is via repeated measurement of humoral antibody titres. We used baseline and convalescent antibody titres measured by haemagglutination inhibition (HI) and viral neutralization (VN) assays against influenza A(H1N1), A(H3N2) and B viruses to investigate the characteristics of antibody rises following virologically confirmed influenza virus infections in participants in a community-based study. Multivariate models were fitted in a Bayesian framework to characterize the distribution of changes in antibody titres following influenza A virus infections. In 122 participants with PCR-confirmed influenza A virus infection, homologous antibody titres rose by geometric means of 1·2- to 10·2-fold after infection with A(H1N1), A(H3N2) and A(H1N1)pdm09. Significant cross-reactions were observed between A(H1N1)pdm09 and seasonal A(H1N1). Antibody titre rises for some subtypes and assays varied by age, receipt of oseltamivir treatment, and recent receipt of influenza vaccination. In conclusion, we provided a quantitative description of the mean and variation in rises in influenza virus antibody titres following influenza virus infection. The multivariate patterns in boosting of antibody titres following influenza virus infection could be taken into account to improve estimates of cumulative incidence of infection in seroepidemiological studies.

journal_name

Epidemiol Infect

authors

Freeman G,Perera RA,Ngan E,Fang VJ,Cauchemez S,Ip DK,Peiris JS,Cowling BJ

doi

10.1017/S0950268816000583

subject

Has Abstract

pub_date

2016-08-01 00:00:00

pages

2306-16

issue

11

eissn

0950-2688

issn

1469-4409

pii

S0950268816000583

journal_volume

144

pub_type

杂志文章
  • Risk factors for gastroenteritis: a nested case-control study.

    abstract::This nested case-control study investigated the risk factors for gastroenteritis in a cohort using rainwater as their primary domestic water source. Consumption of beef [odds ratio (OR) 2·74, 95% confidence interval (CI) 1·56-4·80], handling of raw fresh chicken in the household (OR 1·52, 95% CI 1·02-2·29) and animal ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268810001159

    authors: Rodrigo S,Sinclair M,Wolfe R,Leder K

    更新日期:2011-04-01 00:00:00

  • Differences in survival of Escherichia coli O157:H7 under various conditions that re-enact the cooking of lunches implicated in an outbreak of haemorrhagic diarrhoea.

    abstract::Two elementary schools were served lunches that were cooked in the same kitchen. An outbreak of Escherichia coli O157:H7 occurred at one school where the dishes that were prepared for the school were lukewarm and kept for 33 min at an average temperature of 45 degrees C before serving. However, no outbreak occurred at...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268805004589

    authors: Hara-Kudo Y,Watanabe H,Konuma H

    更新日期:2005-12-01 00:00:00

  • Chlamydia pneumoniae, strain TWAR, as the cause of an outbreak in a boys' school previously called psittacosis.

    abstract::Sera from an outbreak of acute respiratory illness in a boys boarding school originally thought to have been due to psittacosis (1) have been re-examined and evidence is presented that suggests that the outbreak was caused by Chlamydia pneumoniae, strain TWAR (2). ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800030752

    authors: Pether JV,Wang SP,Grayston JT

    更新日期:1989-10-01 00:00:00

  • Coagulase gene polymorphism of Staphylococcus aureus isolates from dairy cattle in different geographical areas.

    abstract::The objectives of this study were to investigate the coagulase gene polymorphism of Staphylococcus aureus isolates obtained from bovine mastitic milk and to determine the resistance of predominant and rare coagulase genotypes to bovine blood neutrophil bactericidal activities. A total of 453 isolates were collected fr...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268899002228

    authors: Su C,Herbelin C,Frieze N,Skardova O,Sordillo LM

    更新日期:1999-04-01 00:00:00

  • Hepatitis C subtype distribution in chronically infected patients with mild liver fibrosis in France: the GEMHEP study.

    abstract::Treatment options for Hepatitis C infection have greatly improved with direct-acting antiviral (DAA) combinations achieving high cure rates. Nevertheless, the cost of this treatment is still high and access to treatment in many countries has been preferentially reserved for patients with more severe fibrosis (F3 and F...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,多中心研究

    doi:10.1017/S0950268819001225

    authors: Semenova T,Nemoz B,Thibault V,Lagathu G,Duverlie G,Brochot E,Trimoulet P,Payan C,Vallet S,Henquell C,Chevaliez S,Bouvier-Alias M,Maylin S,Roque-Afonso AM,Izquierdo L,Lunel-Fabiani F,Marcellin P,Morand P,Leroy V,Larr

    更新日期:2019-01-01 00:00:00

  • Characteristics and TB treatment outcomes in TB patients with viral hepatitis, New York City, 2000-2010.

    abstract::Literature surrounding the burden of and factors associated with hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in persons with tuberculosis (TB) disease remains limited and focused on populations outside the USA. Cross-matched New York City (NYC) TB and viral hepatitis surveillance data were used to es...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814002970

    authors: Bushnell G,Stennis NL,Drobnik AM,Proops DC,Ahuja SD,Bornschlegel K,Fuld J

    更新日期:2015-07-01 00:00:00

  • A geostatistical investigation of agricultural and infrastructural risk factors associated with primary verotoxigenic E. coli (VTEC) infection in the Republic of Ireland, 2008-2013.

    abstract::Ireland reports the highest incidence of verotoxigenic Escherichia coli (VTEC) infection in Europe. This study investigated potential risk factors for confirmed sporadic and outbreak primary VTEC infections during 2008-2013. Overall, 989 VTEC infections including 521 serogroup O157 and 233 serogroup O26 were geo-refer...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026881600193X

    authors: Óhaiseadha C,Hynds PD,Fallon UB,O'Dwyer J

    更新日期:2017-01-01 00:00:00

  • Widespread Legionella pneumophila contamination of dental stations in a dental school without apparent human infection.

    abstract::Following isolation of Legionella pneumophila from a special dental station water circuit, used primarily to cool high-speed dental drills which produce fine aerosols, a case finding and environmental survey was undertaken. Widespread colonization of the dental stations was found and the results suggested that amplifi...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s095026880006698x

    authors: Oppenheim BA,Sefton AM,Gill ON,Tyler JE,O'Mahony MC,Richards JM,Dennis PJ,Harrison TG

    更新日期:1987-08-01 00:00:00

  • The occurrence of hepatitis B and C viruses in Pakistani patients with chronic liver disease and hepatocellular carcinoma.

    abstract::To study the occurrence of hepatitis B virus (HBV) and hepatitis C virus (HCV) in patients with chronic liver disease (CLD) and hepatocellular carcinoma (HCC) in Pakistan, blood samples from 105 sequential patients with biopsy-proven CLD (n = 82) and HCC (n = 23) were tested for HBV and HCV markers. Of the 105, 87 (83...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800001503

    authors: Tong CY,Khan R,Beeching NJ,Tariq WU,Hart CA,Ahmad N,Malik IA

    更新日期:1996-10-01 00:00:00

  • Prevalence of and risk factors for MRSA carriage in companion animals: a survey of dogs, cats and horses.

    abstract::We investigated the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) carriage in a convenience sample of purposely selected populations of dogs, cats and horses in the Greater London area. Swabs from carriage sites were pooled, enriched and processed by standard bacteriological methods. The presence of...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026881000227X

    authors: Loeffler A,Pfeiffer DU,Lindsay JA,Soares Magalhães RJ,Lloyd DH

    更新日期:2011-07-01 00:00:00

  • Epidemiological and clinical characteristics of a familial cluster of COVID-19.

    abstract::We report a family cluster of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection involving five patients in a family cluster in Dazhou, China, including the epidemiological, clinical, laboratory and radiological findings. Three-generation transmission was observed. Through epidemiological investiga...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268820001521

    authors: Sun Y,Tian L,Du X,Wang H,Li Y,Wu R

    更新日期:2020-07-07 00:00:00

  • Pertussis epidemiology prior to the introduction of a maternal vaccination program, Queensland Australia.

    abstract::Pertussis morbidity is highest in infants too young to be fully protected by routine vaccination schedules. Alternate vaccine strategies are required to maximise protection in this age-group. To understand baseline pertussis epidemiology prior to the introduction of the maternal pertussis vaccination program in 2014, ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268817002722

    authors: McHugh L,Viney KA,Andrews RM,Lambert SB

    更新日期:2018-01-01 00:00:00

  • Prevalence of antibodies to Brucella spp. and risk factors related to high-risk occupational groups in Eritrea.

    abstract::In a study of three high-risk occupational groups using Rose Bengal and complement fixation tests, the highest prevalence (7.1%) was found among dairy farm workers and owners in randomly selected dairy-cattle farms, followed by veterinary personnel (4.5%) and inhabitants in pastoralist areas (3.0%). There was no evide...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268802007215

    authors: Omer MK,Assefaw T,Skjerve E,Tekleghiorghis T,Woldehiwet Z

    更新日期:2002-08-01 00:00:00

  • Two sequential outbreaks in two villages illustrate the various modes of transmission of cholera.

    abstract::We investigated two sequential outbreaks of severe diarrhoea in two neighbouring villages of Orissa, in 2005. We conducted descriptive and matched case-control studies. The attack rates were 5.6% (n=62) and 5.2% (n=51), respectively, in the first and second villages. One death was reported in the second village (case ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268808001611

    authors: DAS A,Manickam P,Hutin Y,Pattanaik B,Pal BB,Chhotray GP,Kar SK,Gupte MD

    更新日期:2009-06-01 00:00:00

  • Evaluating vaccination strategies to control foot-and-mouth disease: a model comparison study.

    abstract::Simulation models can offer valuable insights into the effectiveness of different control strategies and act as important decision support tools when comparing and evaluating outbreak scenarios and control strategies. An international modelling study was performed to compare a range of vaccination strategies in the co...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814001927

    authors: Roche SE,Garner MG,Sanson RL,Cook C,Birch C,Backer JA,Dube C,Patyk KA,Stevenson MA,Yu ZD,Rawdon TG,Gauntlett F

    更新日期:2015-04-01 00:00:00

  • The emergence of wildlife species as a source of human rabies infection in Brazil.

    abstract::Forty-five human rabies virus isolates from a wide geographical area of Brazil were characterized using an anti-nucleoprotein monoclonal antibody panel and by partial nucleotide sequencing analysis of the nucleoprotein gene. Three major antigenic groups related to the antigenic variants maintained in domestic dogs, va...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268813000198

    authors: Favoretto SR,de Mattos CC,de Mattos CA,Campos AC,Sacramento DR,Durigon EL

    更新日期:2013-07-01 00:00:00

  • Improved methods of detection of meningococcal DNA from oropharyngeal swabs from cases and contacts of meningococcal disease.

    abstract::In the UK the increasing use of pre-admission parenteral antibiotic therapy in meningococcal disease has lessened the value of routine cultures as a tool to confirm diagnosis, and laboratory confirmation of invasive meningococcal infection is achieved increasingly by non-culture, nucleic acid amplification methods. Th...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268899004367

    authors: Sadler F,Borrow R,Dawson MM,Kaczmarski EB,Cartwright K,Fox AJ

    更新日期:2000-10-01 00:00:00

  • Potential biases in estimates of hepatitis C RNA clearance in newly acquired hepatitis C infection among a cohort of injecting drug users.

    abstract::Estimates of hepatitis C virus (HCV) clearance following acute infection range from 14 to 46%. This wide range is likely to be due to the characteristics of the populations studied and analysis methods. This paper examines how differing definitions of clearance parameters affect estimates of viral clearance in a cohor...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268806006388

    authors: Amin J,Law MG,Micallef J,Jauncey M,Van Beek I,Kaldor JM,Dore GJ

    更新日期:2007-01-01 00:00:00

  • Molecular characterization of capsular polysaccharides and surface protein genes in relation to genetic similarity of group B streptococci isolated from Polish pregnant women.

    abstract::Serotyping, subtyping and genotyping are important tools for epidemiological studies of group B streptococci (GBS). We investigated the genotype distribution of 353 GBS isolates originating from vaginal or rectal carriage to identify capsular serotypes and subtypes based on the surface protein genes of the alpha-like ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268811000616

    authors: Brzychczy-Włoch M,Gosiewski T,Bodaszewska-Lubas M,Adamski P,Heczko PB

    更新日期:2012-02-01 00:00:00

  • The use of the case-crossover design in a continuous common source food-borne outbreak.

    abstract::When applicable, case-crossover studies may be quicker and cheaper to complete than case-control studies. Because time is a major issue in outbreak investigations, we evaluated the interest of this design during a continuous common source food-borne outbreak of salmonellosis for which the vehicle (hamburgers) was also...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268803001006

    authors: Haegebaert S,Duche L,Desenclos JC

    更新日期:2003-10-01 00:00:00

  • Applications of machine learning techniques to predict filariasis using socio-economic factors.

    abstract::Filariasis is one of the major public health concerns in India. Approximately 600 million people spread across 250 districts of India are at risk of filariasis. To predict this disease, a pilot scale study was carried out in 30 villages of Karimnagar district of Telangana from 2004 to 2007 to collect epidemiological a...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268819001481

    authors: Kondeti PK,Ravi K,Mutheneni SR,Kadiri MR,Kumaraswamy S,Vadlamani R,Upadhyayula SM

    更新日期:2019-09-02 00:00:00

  • Association of HIV transmission categories with sociodemographic, viroimmunological and clinical parameters of HIV-infected patients.

    abstract::To analyse sociodemographic, viroimmunological and clinical parameters in different HIV-transmission categories at baseline and during treatment, 3039 patients were followed up for 12 months after the initiation of a nelfinavir-based regimen. Multiple baseline parameters were significantly different in the diverse cat...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268809991282

    authors: Collazos J,Asensi V,Carton JA,Grupo Español para el Estudio Multifactorial de la Adherencia (GEEMA).

    更新日期:2010-07-01 00:00:00

  • An evaluation of dog rabies control in Limpopo province (South Africa).

    abstract::Rabies is a prevalent and re-emerging disease in South Africa particularly in rural areas with high human densities. Outbreaks are frequently reported in the north and eastern parts of this country, probably an indication of inadequacy in the control of the disease. Following the 2005/2006 outbreak in Limpopo, we unde...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268811001233

    authors: Sabeta CT,Mkhize GC,Ngoepe EC

    更新日期:2011-10-01 00:00:00

  • Quantitative risk assessment of the introduction of rabies into Japan through the importation of dogs and cats worldwide.

    abstract::Japan has been free from rabies since 1958. A strict import regimen has been adopted since 2004 consisting of identification of an animal with microchip, two-time rabies vaccination, neutralizing antibody titration test and a waiting period of 180 days. The present study aims to quantitatively assess the risk of rabie...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268816002995

    authors: Kwan NC,Sugiura K,Hosoi Y,Yamada A,Snary EL

    更新日期:2017-04-01 00:00:00

  • Epidemiological investigations on the potential transmissibility of a rare disease: the case of atypical scrapie in Great Britain.

    abstract::Multiple cases of atypical scrapie in the same holding and co-existence with classical scrapie have been reported in Great Britain. A two-stage simulation tool was developed by combining a sampling algorithm and a hierarchical Bayesian model to simulate the number of positive cases of atypical scrapie from: (i) random...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268816000303

    authors: Ortiz-Peláez A,Arnold ME,Vidal-Diez A

    更新日期:2016-07-01 00:00:00

  • Hospitalization rates associated with hepatitis B and HIV co-infection, age and sex in a population-based cohort of people diagnosed with hepatitis C.

    abstract::To determine the extent age, sex and co-infection affect morbidity in people infected with hepatitis C virus (HCV), we performed a population-based study linking HCV notifications in New South Wales, Australia with their hospital (July 2000 to June 2006), hepatitis B virus (HBV) and HIV notification, and death records...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026881000258X

    authors: Gidding HF,Amin J,Dore GJ,Law MG

    更新日期:2011-08-01 00:00:00

  • Effective case/infection ratio of poliomyelitis in vaccinated populations.

    abstract::Recent polio outbreaks in Syria and Ukraine, and isolation of poliovirus from asymptomatic carriers in Israel have raised concerns that polio might endanger Europe. We devised a model to calculate the time needed to detect the first case should the disease be imported into Europe, taking the effect of vaccine coverage...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268816000078

    authors: Bencskó G,Ferenci T

    更新日期:2016-07-01 00:00:00

  • Correlation between electrophoretic types B1 and B2 of carboxylesterase B and host-dependent factors in Escherichia coli septicaemia.

    abstract::Electrophoretic types B1 and B2 of carboxylesterase B produced by strains of Escherichia coli isolated from 100 septicaemia cases were correlated with alpha-haemolysin and mannose resistant haemagglutinin (MRHA) production and with clinical data including eventual underlying diseases, origin of septicaemia and evoluti...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800065559

    authors: Picard B,Goullet P

    更新日期:1988-02-01 00:00:00

  • A viral infection of the hand commonly seen after the feast of sacrifice: human orf (orf of the hand).

    abstract::Orf of the hand is an uncommon zoonotic infection caused by a dermotropic DNA virus that belongs to the Parapoxvirus genus of the family Poxviridae. It is transmitted to humans through contact with infected sheep and goats and is reported as an occupational disease. We report nine cases of human orf seen in the hands ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268805003778

    authors: Uzel M,Sasmaz S,Bakaris S,Cetinus E,Bilgic E,Karaoguz A,Ozkul A,Arican O

    更新日期:2005-08-01 00:00:00

  • B. anthracis in a wool-processing factory: seroprevalence and occupational risk.

    abstract::In a Belgian wool-processing factory, living anthrax spores were found in raw goat hair and air dust, but confirmed anthrax cases had never been reported. Anthrax vaccines are not licensed nor recommended in Belgium. We conducted a B. anthracis seroprevalence study to investigate risk factors associated with positive ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268811001488

    authors: Kissling E,Wattiau P,China B,Poncin M,Fretin D,Pirenne Y,Hanquet G

    更新日期:2012-05-01 00:00:00