Abstract:
:Legionnaires' disease (LD) is a major cause of severe community-acquired pneumonia but the source and mode of transmission are not always apparent, especially in sporadic cases. We hypothesized that LD can be acquired from the air-conditioning systems of motor cars. Swabs were taken from the evaporator compartments of the air-conditioning system of scrapped cars. Healthy subjects who were mainly employees of regional transportation companies were tested for antibody to Legionella pneumophila serogroups 1-6; they also completed a questionnaire. Legionella species were detected in 11/22 scrapped cars by the loop-mediated isothermal amplification method. The prevalence of microplate agglutination titres > or =1:32 was significantly higher in subjects who sometimes used car air-conditioning systems. Although we did not prove a direct link between Legionella spp. in the car evaporator and LD, our findings point to a potential risk of car air-conditioning systems in LD, which needs further investigation.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Sakamoto R,Ohno A,Nakahara T,Satomura K,Iwanaga S,Kouyama Y,Kura F,Noami M,Kusaka K,Funato T,Takeda M,Matsubayashi K,Okumiya K,Kato N,Yamaguchi Kdoi
10.1017/S0950268809002568subject
Has Abstractpub_date
2009-11-01 00:00:00pages
1615-22issue
11eissn
0950-2688issn
1469-4409pii
S0950268809002568journal_volume
137pub_type
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