Abstract:
:The prevalence of Helicobacter pylori infection is decreasing in developed countries. In this study we included 22,612 patients in whom a first culture of gastric biopsy (routinely performed in our medical centres) yielded an interpretable result over a 20-year period (1988-2007) in Brussels. The effects of patients' age, gender and ethnic background were analysed. The overall proportion of H. pylori-infected patients was 37·7%, with a progressive decline over time (P<10(-5)). A gender effect was observed in adults. The lowest infection rate was observed in Western European patients (n=11,238) with respectively 36·2% and 15·2% infected subjects in 1988 and 2007, compared to 71·7% and 40% in North African patients (n=3200) (P<10(-5)). However, no trend of decline was observed over time in North African children aged ≤9 years. These data show the effects of time, age and ethnicity on the prevalence of H. pylori infection, and its complex heterogeneity in the same cosmopolitan urban area.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Miendje Deyi VY,Vanderpas J,Bontems P,Van den Borre C,De Koster E,Cadranel S,Burette Adoi
10.1017/S095026881000110Xsubject
Has Abstractpub_date
2011-04-01 00:00:00pages
572-80issue
4eissn
0950-2688issn
1469-4409pii
S095026881000110Xjournal_volume
139pub_type
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