Abstract:
:It is uncertain whether hospitalization among patients with congestive heart failure (CHF) increases during the influenza season. This retrospective cohort study used influenza surveillance data from the United States (1986-1987 to 1990-1991), clinical information from the Studies of Left Ventricular Dysfunction (SOLVD) database, and daily temperature data from the National Climatic Data Center to assess the effect of influenza season on hospitalizations in this cohort of patients. The overall hospitalization rate was higher during influenza seasons compared to non-influenza seasons [relative risk (RR) 1.08, 95% confidence interval (CI) 1.01-1.16]. Multivariable Cox modelling revealed an adjusted hazard ratio (HR) of 1.11 for hospitalization during the influenza season (95% CI 1.03-1.20, P=0.005). Overall death rates were also higher during influenza seasons than non-influenza seasons (RR 1.09, 95% CI 0.97-1.21), but the corresponding adjusted HR for death was not significant (HR 1.01, 95% CI 0.98-1.24, P=0.11). Patients with CHF have a greater risk of hospitalization during the influenza season than in the non-influenza season, supporting the current belief that patients with CHF should be regarded as a high-risk group.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Sandoval C,Walter SD,Krueger P,Smieja M,Smith A,Yusuf S,Loeb MBdoi
10.1017/S095026880600714Xsubject
Has Abstractpub_date
2007-05-01 00:00:00pages
574-82issue
4eissn
0950-2688issn
1469-4409pii
S095026880600714Xjournal_volume
135pub_type
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