Characterization of cholera outbreak isolates from Namibia, December 2006 to February 2007.

Abstract:

:We report on the first recorded outbreak of cholera in Namibia. From December 2006 to February 2007, more than 250 cases of cholera were reported from the Omusati and Kunene provinces of Namibia. However, only nine bacterial isolates were obtainable for analysis. Isolates were all identified as Vibrio cholerae O1 serotype Inaba biotype El Tor. All isolates were susceptible to ampicillin, augmentin, chloramphenicol, nalidixic acid, ciprofloxacin, tetracycline, kanamycin, imipenem, ceftriaxone and ceftazidime; and they all showed resistance to trimethoprim, sulfamethoxazole and streptomycin. Pulsed-field gel electrophoresis analysis of bacteria incorporating either SfiI or NotI digestion revealed an identical fingerprint pattern for all isolates. These data together with results indicating identical antimicrobial susceptibility profiles for all isolates determined that the outbreak was caused by a single strain of V. cholerae.

journal_name

Epidemiol Infect

authors

Smith AM,Keddy KH,De Wee L

doi

10.1017/S0950268807009685

subject

Has Abstract

pub_date

2008-09-01 00:00:00

pages

1207-9

issue

9

eissn

0950-2688

issn

1469-4409

pii

S0950268807009685

journal_volume

136

pub_type

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