Abstract:
:To determine the incidence, risk factors for, and the influence of bloodstream infections (BSIs) on mortality of patients in intensive-care units (ICUs), prospectively collected data from all patients with a stay in an ICU >48 h, during a 1-year period, were analysed. Of 572 patients, 148 developed a total of 232 BSI episodes (incidence 16.3 episodes/1000 patient-days). Gram-negative organisms with high level of resistance to antibiotics were the most frequently isolated pathogens (157 strains, 67.8%). The severity of illness on admission, as estimated by APACHE II score (OR 1.07, 95% CI 1.04-1.1, P<0.001), the presence of acute respiratory distress syndrome (OR 3.57, 95% CI 1.92-6.64, P<0.001), and a history of diabetes mellitus (OR 2.37, 95% CI 1.36-4.11, P=0.002) were risk factors for the occurrence of BSI whereas the development of an ICU-acquired BSI was an independent risk factor for death (OR 1.76, 95% CI 1.11-2.78, P=0.015). Finally, the severity of organ dysfunction on the day of the first BSI episode, as estimated by SOFA score, and the level of serum albumin, independently affected the outcome (OR 1.44, 95% CI 1.22-1.7, P<0.001 and OR 0.47, 95% CI 0.23-0.97, P=0.04 respectively).
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Pratikaki M,Platsouka E,Sotiropoulou C,Vassilakopoulos T,Paniara O,Roussos C,Routsi Cdoi
10.1017/S0950268808001271subject
Has Abstractpub_date
2009-05-01 00:00:00pages
727-35issue
5eissn
0950-2688issn
1469-4409pii
S0950268808001271journal_volume
137pub_type
杂志文章abstract::Two elementary schools were served lunches that were cooked in the same kitchen. An outbreak of Escherichia coli O157:H7 occurred at one school where the dishes that were prepared for the school were lukewarm and kept for 33 min at an average temperature of 45 degrees C before serving. However, no outbreak occurred at...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268805004589
更新日期:2005-12-01 00:00:00
abstract::Historically, the highest incidence rates of invasive Haemophilus influenzae disease in the world were found in North American and Australian Indigenous children. Although immunization against H. influenzae type b (Hib) led to a marked decrease in invasive Hib disease in countries where it was implemented, this diseas...
journal_title:Epidemiology and infection
pub_type: 杂志文章,评审
doi:10.1017/S0950268814000405
更新日期:2014-07-01 00:00:00
abstract::Two hundred and seventy-five consecutive clinical isolates of coagulase-negative staphylococci, including strains associated with disease, contaminants and skin colonizers, were speciated, tested for slime production and for their sensitivity to a range of antibiotics. Staphylococcus epidermidis was the most commonly ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800029265
更新日期:1988-08-01 00:00:00
abstract::A retrospective cohort study was conducted from 1 January 2006 to 31 December 2009 in Michigan to estimate the prevalence of HIV and hepatitis co-infection and identify associated factors. The prevalence of co-infection was 4.1% [95% confidence interval (CI) 3.8-4.5]. Multivariable logistic regression analysis reveale...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268813000538
更新日期:2013-12-01 00:00:00
abstract::We describe recent epidemiological changes in salmonellosis. Linking 1968-2000 National Salmonella Surveillance System to census data, we calculated population-based age- and sex-stratified rates of non-urinary salmonellosis for the top 30 non-typhoidal serotypes. Using 1996-1997, 1998-1999, and 2000-2001 population-b...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268807009594
更新日期:2008-08-01 00:00:00
abstract::In 2005, a serological study was carried out on horses in five ecologically contrasted zones of the Senegal River basin (Senegal) to assess West Nile virus (WNV) transmission and investigate underlying environmental risk factors. In each study zone, horses were randomly selected and blood samples taken. A land-cover m...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S095026881000035X
更新日期:2010-11-01 00:00:00
abstract::Three sources of data (general practice episode data from the Weekly Returns Service of the Royal College of General Practitioners, national hospital admission data for England and national mortality data by date of death) were examined separately in each winter (1994/1995 to 1999/2000) to investigate the impact of in...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268804003231
更新日期:2005-04-01 00:00:00
abstract::This study aimed to reveal the associated risk factors for latent tuberculosis infection (LTBI) detected by T-SPOT.TB assay among health care workers (HCWs) at different working locations or job categories in China. This cross-sectional study included 934 HCWs who underwent the T-SPOT.TB assay. Demographic and social ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268818002777
更新日期:2019-01-01 00:00:00
abstract::The aim of this study was to estimate the prevalence of hepatitis B exposure in the population of the Republic of Ireland, by measuring the prevalence of hepatitis B anti-core antibody in oral fluid collected by postal survey. A random multi-stage stratified sample of Irish households was obtained, using the Irish ele...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s095026880000491x
更新日期:2000-12-01 00:00:00
abstract::A serological study of hepatitis A was carried out in low-income areas scheduled for a major sanitation programme in Rio de Janeiro, Brazil. Blood spots were collected by finger puncture and transported on filter paper, and total antibodies to hepatitis A virus were detected by ELISA. Households were also interviewed ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268801005945
更新日期:2001-10-01 00:00:00
abstract::Twenty progesterone-treated TO mice were infected intravaginally with Mycoplasma pulmonis. One month later, ten of the mice were given oestradiol which changed the reproductive cycle to the oestrous phase and within a week resulted in eradication of the organisms from six of them; vaginal persistence in the other mice...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800047749
更新日期:1990-08-01 00:00:00
abstract::Horizontal transmission of Campylobacter jejuni was investigated in campylobacter-free broiler chicks. One hundred and twenty chicks housed individually, were provided with water containing 10(2)-10(9) c.f.u./ml C. jejuni. Colonization was rapid [47 of 73 (64%) positive cloacal cultures within 3 days and 65 of 73 (89%...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800054571
更新日期:1990-02-01 00:00:00
abstract::There is concern that widespread usage of ertapenem may promote cross-resistance to other carbapenems. To analyse the impact that adding ertapenem to our hospital formulary had on usage of other broad-spectrum agents and on susceptibilities of nosocomial Enterobacteriaceae and Pseudomonas isolates, we performed interr...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268811000082
更新日期:2012-01-01 00:00:00
abstract::This study aimed to estimate the prevalence and risk factors for hepatitis C virus (HCV) infection in Mexican Americans living in South Texas. We tested plasma for the presence of HCV antibody from the Cameron County Hispanic Cohort (CCHC), a randomized, population-based cohort in an economically disadvantaged Mexican...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268815001247
更新日期:2016-01-01 00:00:00
abstract::We analysed the data from the control group in a typhoid vaccine trial in Karachi to assess the differences in individual-, household- and cluster-level characteristics for developing typhoid fever. The annual incidence of typhoid in children aged 2-16 years in the control arm of the vaccine trial was 151/100 000 popu...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268811000938
更新日期:2012-04-01 00:00:00
abstract::To assess the burden of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in a high-risk population, the monthly incidence of laboratory-confirmed MRSA in service members/trainees stationed at Fort Benning, Georgia, USA without hospitalization or surgery documented 30 days prior to infection w...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268810000142
更新日期:2010-05-01 00:00:00
abstract::A total of 598 isolates of Shigella species (24 S. dysenteriae, 254 S. flexneri, 30 S. boydii, 290 S. sonnei) submitted to the Ontario Public Health Laboratories in 1990 were tested for their susceptibility to 14 antimicrobial agents by the agar dilution method. Overall 79.6% of isolates were resistant to one or more ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800050457
更新日期:1992-12-01 00:00:00
abstract::UK guidelines recommend routine HIV testing in high prevalence emergency departments (ED) and targeted testing for HBV and HCV. The 'Going Viral' campaign implemented opt-out blood-borne virus (BBV) testing in adults in a high prevalence ED, to assess seroprevalence, uptake, linkage to care (LTC) rates and staff time ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268818000870
更新日期:2018-06-01 00:00:00
abstract::Between March and July 2003, 671 cases of severe acute respiratory syndrome (SARS) were diagnosed in Taiwan with a total of 84 fatalities. After the epidemic, a serological survey was conducted involving the asymptomatic household contacts. Household contacts of 13 index patients were enrolled in the study. Contact hi...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268805004541
更新日期:2005-12-01 00:00:00
abstract::Previous studies have demonstrated that type 1 diabetes mellitus (T1DM) could be triggered by an early childhood infection. Whether maternal infection during pregnancy is associated with T1DM in offspring is unknown. Therefore, we aimed to study the association using a systematic review and meta-analysis. Eighteen stu...
journal_title:Epidemiology and infection
pub_type: 杂志文章,meta分析
doi:10.1017/S0950268818002455
更新日期:2018-12-01 00:00:00
abstract::Isolates of Streptococcus pyogenes from vaginal swabs of children with vulvovaginitis received at Nottingham Public Health Laboratory during 1986-9 were studied. A total of 159 isolates was made during the 4 years, increasing from 17 in 1986 to 64 in 1989 and accounting for 11% of all vaginal swabs received from child...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800067509
更新日期:1991-06-01 00:00:00
abstract::Mosquito-borne Sindbis virus (SINV) causes rash-arthritis syndrome in Finland. Major outbreaks with approximately 7-year cycles have caused substantial burden of illness. Forest dwelling grouse are suspected to be amplifying hosts, with the infection transmitted to humans by mosquito bites. SINV infection surveillance...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S095026881200249X
更新日期:2013-09-01 00:00:00
abstract::There is a paucity of information on the risk from potable water in non-passenger merchant vessels (NPMVs) particularly with regard to Legionella and other bacteria. This retrospective study examined water samples from 550 NPMVs docked in eight UK ports. A total of 1027 samples from 412 NPMVs were examined for total a...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268816002715
更新日期:2017-03-01 00:00:00
abstract::A review of the epidemiology of invasive pneumococcal disease in Scotland was carried out using data from laboratory-based systems during the period 1988-99. This comprised 5456 (90.8%) isolates of Streptococcus pneumoniae from blood, 467 (7.8%) from cerebrospinal fluid (CSF) and 84 (1.4%) from other sterile sites. Th...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:
更新日期:2002-04-01 00:00:00
abstract::Orf virus has a worldwide distribution among sheep and goats. The hypersensitivity reaction erythema multiforme (EM) is a known complication of orf infection in humans; however, its occurrence is poorly understood and has not been extensively reviewed. We present two unrelated cases of orf-associated EM, and a review ...
journal_title:Epidemiology and infection
pub_type: 杂志文章,评审
doi:10.1017/S0950268814000879
更新日期:2015-01-01 00:00:00
abstract::Virus surveillance of Northern Ireland recreational waters, between April 1986 and May 1989 demonstrated widespread enteroviral contamination of coastal and inland waters. In 1986, enteroviruses were detected in 4 of 46 (8.7%) water samples, collected from 6 coastal bathing waters. In 1987, 49 of 107 (45.8%) samples, ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800050020
更新日期:1992-06-01 00:00:00
abstract::We propose an age-structured mathematical model for respiratory syncytial virus in which children aged <1 year are especially considered. Real data on hospitalized children in the Spanish region of Valencia were used in order to determine some seasonal parameters of the model. Weekly predictions of the number of child...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268809991373
更新日期:2010-06-01 00:00:00
abstract::The presence of Legionella spp. in the water of a Portuguese spa was ascertained during the spa season, between May and November. Simultaneously the prevalence of anti-legionella antibodies in people attending the spa was also investigated. The antibody titres of 172 randomly selected patients and 42 therapists were d...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800058143
更新日期:1995-08-01 00:00:00
abstract::We examined multistate outbreaks attributed to raw tomatoes in the United States from 1990 to 2010. We summarized the demographic and epidemiological characteristics of 15 outbreaks resulting in 1959 illnesses, 384 hospitalizations, and three deaths. Most (80%) outbreaks were reported during 2000-2010; 73% occurred Ma...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268814002167
更新日期:2015-05-01 00:00:00
abstract::This study aimed to estimate the natural history and transmission parameters based on experimental viral shedding and symptom dynamics in order to understand the key epidemiological factors that characterize influenza (sub)type epidemics. A simple statistical algorithm was developed by combining a well-defined mathema...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268809991178
更新日期:2010-06-01 00:00:00