Phylogenetic and antigenic analysis of influenza A(H3N2) viruses isolated from conscripts receiving influenza vaccine prior to the epidemic season of 1998/9.

Abstract:

:Roughly half (54%) of the 910 young conscripts at a garrison in Finland were vaccinated with commercial influenza vaccines in autumn 1998. During the influenza outbreak in February 1999, 12 H3N2-subtype virus strains were isolated from vaccinated patients, and 11 such strains were isolated from unvaccinated patients. The isolates were related to the vaccine strain A/Sydney/5/97 and could be classified into three subgroups based on sequence variation in the HA1 gene coding for the variable domain of viral haemagglutinin (HA). A total of 6-10 amino-acid substitutions in HA1, three of these in the receptor-binding site, differentiated the field strains from the vaccine virus. In haemagglutination inhibition (HI) tests, eight strains from the study population exhibited reduced reactivity with a variety of antisera including human post-vaccination sera. Six of these strains were isolated from vaccinated and two from unvaccinated patients. The reduced reactivity did not correlate with particular amino-acid changes in HA1. We suggest that low-reactivity viruses may have an advantage over other co-circulating variants under some circumstances characterized by enhanced immunity-mediated selection and high infection pressure. Whether the frequency of these viruses increased in our vaccinated study population cannot be determined, nor can their effect on vaccine efficacy.

journal_name

Epidemiol Infect

authors

Pyhälä R,Ikonen N,Haanpää M,Santanen R,Tervahauta R

doi

10.1017/s0950268802007410

subject

Has Abstract

pub_date

2002-10-01 00:00:00

pages

347-53

issue

2

eissn

0950-2688

issn

1469-4409

journal_volume

129

pub_type

杂志文章
  • Usutu virus: A new threat?

    abstract::Usutu virus (USUV) is an emerging arbovirus that was first isolated in South Africa in 1959. This Flavivirus is maintained in the environment through a typical enzootic cycle involving mosquitoes and birds. USUV has spread to a large part of the European continent over the two decades mainly leading to substantial avi...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,评审

    doi:10.1017/S0950268819001213

    authors: Clé M,Beck C,Salinas S,Lecollinet S,Gutierrez S,Van de Perre P,Baldet T,Foulongne V,Simonin Y

    更新日期:2019-01-01 00:00:00

  • Characterization of cholera outbreak isolates from Namibia, December 2006 to February 2007.

    abstract::We report on the first recorded outbreak of cholera in Namibia. From December 2006 to February 2007, more than 250 cases of cholera were reported from the Omusati and Kunene provinces of Namibia. However, only nine bacterial isolates were obtainable for analysis. Isolates were all identified as Vibrio cholerae O1 sero...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268807009685

    authors: Smith AM,Keddy KH,De Wee L

    更新日期:2008-09-01 00:00:00

  • Human listeriosis in Britain, 1967-85, a summary of 722 cases. 2. Listeriosis in non-pregnant individuals, a changing pattern of infection and seasonal incidence.

    abstract::Clinical information was collected on 722 cases of Listeria monocytogenes infections in humans occurring in Britain between 1967 and 1985. This series comprised 34% (248 cases) associated with pregnancy and 66% (474 cases) in non-pregnant adults and juveniles. The cases not associated with pregnancy comprised: 76% in ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800059355

    authors: McLauchlin J

    更新日期:1990-04-01 00:00:00

  • Assessment of areas at increased risk for poliovirus circulation in Ecuador.

    abstract::To assess areas at risk for poliovirus circulation in Ecuador, we first selected provinces at highest risk based on low immunization coverage with three doses of oral poliovirus vaccine, and a low number of reported cases of acute flaccid paralysis (AFP). Subsequently, we reviewed discharge data for the period 1996--2...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,多中心研究

    doi:10.1017/s0950268804002626

    authors: Dayan GH,Rodríguez R,Vinjé J,Vásconez N,Cáceres V,Gregoricus N,Sobsey M,Landaverde M

    更新日期:2004-10-01 00:00:00

  • Antigenic and genetic analyses of eight influenza C strains isolated in various areas of Japan during 1985-9.

    abstract::Eight strains of influenza C virus isolated in various areas of Japan between January 1985 and January 1989 were compared using monoclonal antibodies to the haemagglutinin-esterase (HE) glycoproteins and by oligonucleotide mapping of total vRNA. Five of six strains isolated during 1986-9 were closely related to one an...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800049827

    authors: Ohyama S,Adachi K,Sugawara K,Hongo S,Nishimura H,Kitame F,Nakamura K

    更新日期:1992-04-01 00:00:00

  • The role of symptomatic presentation in influenza A transmission risk.

    abstract::Computer models can be useful in planning interventions against novel strains of influenza. However such models sometimes make unsubstantiated assumptions about the relative infectivity of asymptomatic and symptomatic cases, or conversely assume there is no impact at all. Using household-level data from known-index st...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268816002740

    authors: Wardell R,Prem K,Cowling BJ,Cook AR

    更新日期:2017-03-01 00:00:00

  • Campylobacter enteritis in Saudi Arabia.

    abstract::A 12-month survey on the incidence of campylobacter infection in 1217 patients with diarrhoea was carried out in Jeddah, Saudi Arabia. Campylobacters were isolated from 55 (4.5%) patients, second in prevalence to salmonellas (6.2%). Shigellas were isolated from 4.2% of patients. Campylobacter isolation rates were high...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800049499

    authors: Zaman R

    更新日期:1992-02-01 00:00:00

  • Dengue, chikungunya and zika virus coinfection: results of the national surveillance during the zika epidemic in Colombia.

    abstract::Our objective was to determine the frequency of zika (ZIKV), chikungunya (CHIKV) and dengue (DENV) virus coinfection and describe the mortality cases that occurred during the epidemiologic surveillance of the ZIKV epidemic in Colombia. We analysed all cases of suspected ZIKV infection that were reported to the Nationa...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026881800359X

    authors: Mercado-Reyes M,Acosta-Reyes J,Navarro-Lechuga E,Corchuelo S,Rico A,Parra E,Tolosa N,Pardo L,González M,Martìn-Rodriguez-Hernández J,Karime-Osorio L,Ospina-Martinez M,Rodriguez-Perea H,Del Rio-Pertuz G,Viasus D

    更新日期:2019-01-01 00:00:00

  • Expected background rates of latent TB infection in London inner city schools: lessons from a TB contact investigation exercise in a secondary school.

    abstract::Following an extensive contact tracing exercise at a school in a London borough with one of highest tuberculosis (TB) rates in England, we estimated the background prevalence of latent TB infection to be significantly less than the widely accepted 10%. We screened 271 pupils aged 14-15 years in two groups: 96 pupils i...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268818002327

    authors: Anaraki S,Bell AJ,Perkins S,Murphy S,Dart S,Anderson C

    更新日期:2018-12-01 00:00:00

  • Impact of self-financed rotavirus vaccines on hospital stays and costs in Spain after a 3-year introductory period.

    abstract::Vaccination has reduced rotavirus hospitalizations by 25% in European regions with low-moderate vaccine availability. We aimed to quantify the reduction in hospital costs after the longest period in which Rotarix® and Rotateq® were simultaneously commercially available in Spain. Cases, length of stay (LOS), and diagno...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268817000620

    authors: Redondo-González O,Tenías-Burillo JM,Ruiz-Gonzalo J

    更新日期:2017-07-01 00:00:00

  • The seroepidemiology of pertussis in Australia during an epidemic period.

    abstract::Studying the epidemiology of pertussis and impact of differing vaccine schedules is difficult because of differing methods of case ascertainment. The advent of internationally standardized serological diagnosis for recent infection has allowed comparison of age-specific pertussis infection among European countries and...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026880600625X

    authors: Cagney M,MacIntyre CR,McIntyre P,Puech M,Giammanco A

    更新日期:2006-12-01 00:00:00

  • Multistate outbreak of Salmonella Paratyphi B variant L(+) tartrate(+) and Salmonella Weltevreden infections linked to imported frozen raw tuna: USA, March-July 2015.

    abstract::Foodborne non-typhoidal salmonellosis causes approximately 1 million illnesses annually in the USA. In April 2015, we investigated a multistate outbreak of 65 Salmonella Paratyphi B variant L(+) tartrate(+) infections associated with frozen raw tuna imported from Indonesia, which was consumed raw in sushi. Forty-six (...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268818001462

    authors: Hassan R,Tecle S,Adcock B,Kellis M,Weiss J,Saupe A,Sorenson A,Klos R,Blankenship J,Blessington T,Whitlock L,Carleton HA,Concepción-Acevedo J,Tolar B,Wise M,Neil KP

    更新日期:2018-08-01 00:00:00

  • An overview of the epidemic of highly pathogenic H5N1 avian influenza virus in Egypt: epidemiology and control challenges.

    abstract::Emergence of the highly pathogenic avian influenza (HPAI) H5N1 virus in Egypt in mid-February 2006 caused significant losses for the poultry industry and constituted a potential threat to public health. Since late 2007, there has been increasing evidence that stable lineages of H5N1 viruses are being established in ch...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,评审

    doi:10.1017/S0950268810003122

    authors: Abdelwhab EM,Hafez HM

    更新日期:2011-05-01 00:00:00

  • Differences in survival of Escherichia coli O157:H7 under various conditions that re-enact the cooking of lunches implicated in an outbreak of haemorrhagic diarrhoea.

    abstract::Two elementary schools were served lunches that were cooked in the same kitchen. An outbreak of Escherichia coli O157:H7 occurred at one school where the dishes that were prepared for the school were lukewarm and kept for 33 min at an average temperature of 45 degrees C before serving. However, no outbreak occurred at...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268805004589

    authors: Hara-Kudo Y,Watanabe H,Konuma H

    更新日期:2005-12-01 00:00:00

  • Changing epidemiology of cholera due to Vibrio cholerae O1 and O139 Bengal in Dhaka, Bangladesh.

    abstract::At the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR, B) Dhaka we studied the trends in cholera for the period January 1992 to May 1995. Vibrio cholerae O139 Bengal emerged as a second aetiologic agent of cholera in Dhaka in January 1993. In 1993, the majority of cholera cases was due to V. c...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800052572

    authors: Faruque AS,Fuchs GJ,Albert MJ

    更新日期:1996-06-01 00:00:00

  • A longitudinal study of an endemic disease in its wildlife reservoir: cowpox and wild rodents.

    abstract::Cowpox is an orthopoxvirus infection endemic in European wild rodents, but with a wide host range including human beings. In this longitudinal study we examined cowpox in two wild rodent species, bank voles Clethrionomys glareolus and wood mice Apodemus sylvaticus, to investigate the dynamics of a virus in its wild re...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268899003799

    authors: Hazel SM,Bennett M,Chantrey J,Bown K,Cavanagh R,Jones TR,Baxby D,Begon M

    更新日期:2000-06-01 00:00:00

  • Diphtheria outbreak in Maranhão, Brazil: microbiological, clinical and epidemiological aspects.

    abstract::We describe microbiological, clinical and epidemiological aspects of a diphtheria outbreak that occurred in Maranhão, Brazil. The majority of the 27 confirmed cases occurred in partially (n = 16) or completely (n = 10) immunized children (n = 26). Clinical signs and characteristic symptoms of diphtheria such as cervic...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814001241

    authors: Santos LS,Sant'anna LO,Ramos JN,Ladeira EM,Stavracakis-Peixoto R,Borges LL,Santos CS,Napoleão F,Camello TC,Pereira GA,Hirata R,Vieira VV,Cosme LM,Sabbadini PS,Mattos-Guaraldi AL

    更新日期:2015-03-01 00:00:00

  • Group L beta-haemolytic streptococcal infection in meat handlers: another streptococcal zoonosis?

    abstract::Group L, beta-haemolytic streptococci can cause infection in dogs, pigs, cattle and sheep but there have been very few reports in man. In studies of skin infection in meat handlers we cultured group L streptococci from clinically infected wounds, impetigo and paronychia of 15 patients involved in the slaughter and pro...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800067728

    authors: Barnham M,Neilson DJ

    更新日期:1987-10-01 00:00:00

  • Age, influenza pandemics and disease dynamics.

    abstract::The world is currently confronting the first influenza pandemic of the 21st century [caused by a novel pandemic influenza A (H1N1) virus]. Earlier pandemics have been characterized by age distributions that are distinct from those observed with seasonal influenza epidemics, with higher attack rates (and correspondingl...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268810000579

    authors: Greer AL,Tuite A,Fisman DN

    更新日期:2010-11-01 00:00:00

  • Exposure of rabbits to ultraviolet light-inactivated rabbit haemorrhagic disease virus (RHDV) and subsequent challenge with virulent virus.

    abstract::This study investigated whether exposure to inactivated rabbit haemorrhagic disease virus (RHDV) can produce an antigenic response in rabbits and protect them from a subsequent challenge with virulent virus. The aim was to determine if the spreading of baits containing RHDV, which is a common management practice in Ne...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268805003754

    authors: Henning J,Meers J,Davies PR

    更新日期:2005-08-01 00:00:00

  • Comparison of different vaccines and induced immune response against Campylobacter jejuni colonization in the infant mouse.

    abstract::The degree of protection conferred by vaccinated dams on infant mice against colonization by Campylobacter jejuni depended on the bacterial strain, preparation, and route of administration of the vaccine. In some instances of homologous protection, serum bactericidal titres correlated well with protection. However, bo...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800029940

    authors: Abimiku AG,Dolby JM,Borriello SP

    更新日期:1989-04-01 00:00:00

  • Antimicrobial resistance in commensal Escherichia coli in veal calves is associated with antimicrobial drug use.

    abstract::The aim of this study was to determine the association between farm management factors, including antimicrobial drug usage, and resistance in commensal Escherichia coli isolates from the faeces of white veal calves. Ninety E. coli isolates from one pooled sample per farm (n = 48) were tested for their phenotypical res...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268813002665

    authors: Bosman AB,Wagenaar JA,Stegeman JA,Vernooij JC,Mevius DJ

    更新日期:2014-09-01 00:00:00

  • Salmonella typhimurium phage type 141 infections in Sheffield during 1984 and 1985: association with hens' eggs.

    abstract::Food poisoning due to Salmonella typhimurium phage type 141 was unusual in the Sheffield area before 1984. The sudden increase in incidence of this phage type during 1984 and 1985, and its causative role in several small outbreaks in this period have been investigated. Epidemiological and laboratory investigations sug...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s095026880002923x

    authors: Chapman PA,Rhodes P,Rylands W

    更新日期:1988-08-01 00:00:00

  • Molecular epidemiology of norovirus strains circulating in Ireland from 2003 to 2004.

    abstract::Since 2002, the burden of norovirus (NoV) infection in Ireland has increased. Outbreaks in institutional settings are the most common causing widespread disruption to health service delivery. This is the first national study of NoV in the Republic of Ireland and its aim was to identify the major NoV strains circulatin...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268806006121

    authors: Waters A,Coughlan S,Dunford L,Hall WW

    更新日期:2006-10-01 00:00:00

  • Prevalence of the genes for shigella enterotoxins 1 and 2 among clinical isolates of shigella in Israel.

    abstract::Two enterotoxins, shigella enterotoxin 1 (SHET1) and shigella enterotoxin 2 (SHET2) have been recently characterized and are believed to play a role in the clinical manifestation of shigellosis. One hundred and twenty-one isolates of Shigella spp. of 13 different serotypes and variants and 10 isolates of enteroinvasiv...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268802006866

    authors: Yavzori M,Cohen D,Orr N

    更新日期:2002-06-01 00:00:00

  • Important roles of public playgrounds in the transmission of hand, foot, and mouth disease.

    abstract::Intra-home and kindergarten transmissions were the reported major modes of hand, foot, and mouth disease (HFMD) transmission in preschool children. However, infection at home is not common and 65-80% of cases do not attend preschool. We conducted a matched case-control study to explore the role of public playgrounds i...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814002301

    authors: Xie YH,Chongsuvivatwong V,Tan Y,Tang ZhZ,Sornsrivichai V,McNeil EB

    更新日期:2015-05-01 00:00:00

  • Temporal dynamics of rabies in a wildlife host and the risk of cross-species transmission.

    abstract::An epidemiological model was developed for rabies, linking the risk of disease in a secondary species (cats) to the temporal dynamics of disease in a wildlife reservoir (raccoons). Data were obtained from cats, raccoons, and skunks tested for rabies in the northeastern United States during 1992-2000. An epizootic algo...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268804002067

    authors: Gordon ER,Curns AT,Krebs JW,Rupprecht CE,Real LA,Childs JE

    更新日期:2004-06-01 00:00:00

  • Optimal design of studies of influenza transmission in households. II: comparison between cohort and case-ascertained studies.

    abstract::Both case-ascertained household studies, in which households are recruited after an 'index case' is identified, and household cohort studies, where a household is enrolled before the start of the epidemic, may be used to test and estimate the protective effect of interventions used to prevent influenza transmission. A...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268813001623

    authors: Klick B,Nishiura H,Leung GM,Cowling BJ

    更新日期:2014-04-01 00:00:00

  • Characterization of a new genotype of measles virus detected in China and England.

    abstract::We report the co-circulation of a new lineage of measles virus (MV) and an Edmonston-like (Ed-like) genotype of MV in China during 1995-7. Sequence analysis of 25 strains was performed on a 282 nucleotides (nt) region of the nucleoprotein (N) gene, a 450-nt region of the haemagglutinin (H) gene and a 152-nt region of ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268898001666

    authors: Jin L,Sun YJ,Ge L,Brown DW

    更新日期:1998-12-01 00:00:00

  • Risk factors for recent toxoplasma infection in pregnant women in Naples.

    abstract::Effective primary prevention of congenital toxoplasmosis requires up to date information on locally relevant risk factors for infection in pregnant women. In Naples, risk factors for toxoplasma infection were compared in recently infected women (as assessed by detection of specific IgM in serum) and susceptible, IgG n...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800052675

    authors: Buffolano W,Gilbert RE,Holland FJ,Fratta D,Palumbo F,Ades AE

    更新日期:1996-06-01 00:00:00