The relationship between socioeconomic indices and potentially zoonotic pathogens carried by wild Norway rats: a survey in Rhône, France (2010-2012).

Abstract:

:Leptospira interrogans, hantaviruses (particularly Seoul virus), hepatitis E virus (HEV), and Toxoplasma gondii are rat-associated zoonoses that are responsible for human morbidity and mortality worldwide. This study aimed to describe the infection patterns of these four pathogens in wild rats (Rattus norvegicus) across socioeconomic levels in neighbourhoods in Lyon, France. The infection or exposure status was determined using polymerase chain reaction or serology for 178 wild rats captured in 23 locations; additionally, confirmatory culture or mouse inoculation was performed. Multivariate logistic regression analyses were used to investigate whether morphological and socioeconomic data could predict the infection status of the rats. This study revealed that the rat colony's age structure may influence the prevalence of L. interrogans, hantavirus, and HEV. In addition, areas with high human population densities and low incomes may be associated with a greater number of infected rats and an increased risk of disease transmission.

journal_name

Epidemiol Infect

authors

Ayral F,Artois J,Zilber AL,Widén F,Pounder KC,Aubert D,Bicout DJ,Artois M

doi

10.1017/S0950268814001137

subject

Has Abstract

pub_date

2015-02-01 00:00:00

pages

586-99

issue

3

eissn

0950-2688

issn

1469-4409

pii

S0950268814001137

journal_volume

143

pub_type

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