Abstract:
:Mycobacterium avium subspecies paratuberculosis (Map), the cause of ruminant paratuberculosis, has been proposed as the causative agent of Crohn's disease. The objective of this study was to determine whether exposure to clinical cases of bovine paratuberculosis was a risk factor for Crohn's disease. A questionnaire was sent to dairy farmers living on premises where the occurrence or absence of clinical cases of bovine paratuberculosis had previously been determined. The prevalence of Crohn's disease was found to be similar to that reported in other studies in the United Kingdom and showed no association with bovine paratuberculosis. There was, however, a univariate association with geographical region. Ulcerative colitis showed univariate associations with age, frequency of contact with cattle and with smoking. The results do not support the hypothesis that Map plays a causative role in the aetiology of Crohn's disease.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Jones PH,Farver TB,Beaman B,Cetinkaya B,Morgan KLdoi
10.1017/S0950268805004681subject
Has Abstractpub_date
2006-02-01 00:00:00pages
49-56issue
1eissn
0950-2688issn
1469-4409pii
S0950268805004681journal_volume
134pub_type
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