Quantifying the contribution of asymptomatic infection to the cumulative incidence.

Abstract:

:Many infectious diseases in humans may manifest with no or mild symptoms. While numerous studies have estimated the proportion of infectious individuals in whom symptoms are absent during the entire course of infection, the contribution of asymptomatic cases to the overall cumulative incidence is difficult to untangle. Here, with a mathematical model, we provide a simple analytical formula to quantify this contribution and highlight the potential for large errors that can arise when naively estimating it.

journal_name

Epidemiol Infect

authors

Champredon D,Moghadas SM

doi

10.1017/S0950268817000115

subject

Has Abstract

pub_date

2017-04-01 00:00:00

pages

1256-1258

issue

6

eissn

0950-2688

issn

1469-4409

pii

S0950268817000115

journal_volume

145

pub_type

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