Herpes simplex virus encephalitis in Peru: a multicentre prospective study.

Abstract:

:Herpes simplex virus (HSV) is one of the most commonly identified infectious aetiologies of encephalitis in North America and Europe. The epidemiology of encephalitis beyond these regions, however, is poorly defined. During 2009-2012 we enrolled 313 patients in a multicentre prospective study of encephalitis in Peru, 45 (14·4%) of whom had confirmed HSV infection. Of 38 patients with known HSV type, 84% had HSV-1 and 16% had HSV-2. Patients with HSV infection were significantly more likely to present in the summer months (44·4% vs. 20·0%, P = 0·003) and have nausea (60·0% vs. 39·8%, P = 0·01) and rash (15·6% vs. 5·3%, P = 0·01) compared to patients without HSV infection. These findings highlight differences in the epidemiology and clinical presentation of HSV encephalitis outside of the Northern Hemisphere that warrant further investigation. Furthermore, there is an urgent need for improved HSV diagnostic capacity and availability of intravenous acyclovir in Peru.

journal_name

Epidemiol Infect

authors

Montano SM,Mori N,Nelson CA,Ton TG,Celis V,Ticona E,Sihuincha M,Tilley DH,Kochel T,Zunt JR,Meningoencephalitis Working Group.

doi

10.1017/S0950268815003222

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

1673-8

issue

8

eissn

0950-2688

issn

1469-4409

pii

S0950268815003222

journal_volume

144

pub_type

杂志文章,多中心研究
  • Emergence of multidrug-resistant Salmonella enterica serotype Typhi with decreased ciprofloxacin susceptibility in Bangladesh.

    abstract::During 1989-2002, we studied the antimicrobial resistance of 3928 blood culture isolates of Salmonella enterica serotype Typhi (S. Typhi) in Dhaka, Bangladesh. Overall 32% (1270) of the strains were multidrug-resistant (MDR, resistant to chloramphenicol, ampicillin and trimethoprim-sulphamethoxazole); first detected i...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268805004759

    authors: Rahman M,Siddique AK,Shoma S,Rashid H,Salam MA,Ahmed QS,Nair GB,Breiman RF

    更新日期:2006-04-01 00:00:00

  • An analysis of coronavirus disease 2019 with spline regression at province level during first-level response to major public health emergency out of Hubei, China.

    abstract::This study aims to locate the knots of cumulative coronavirus disease 2019 (COVID-19) case number during the first-level response to public health emergency in the provinces of China except Hubei. The provinces were grouped into three regions, namely eastern, central and western provinces, and the trends between adjac...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026882000312X

    authors: Liang C,Shen L

    更新日期:2021-01-05 00:00:00

  • Surveillance of listeriosis in the Tel Aviv District, Israel, 2010-2015.

    abstract::This study analyses the epidemiologic, clinical and molecular findings of all culture-confirmed cases of listeriosis notified from 2010 to 2015 in the Tel Aviv District, which is known to have high rates of listeriosis. All clinical isolates of Listeria monocytogenes were subtyped using two-enzyme pulsed-field gel ele...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268817003004

    authors: Salama M,Amitai Z,Ezernitchi AV,Sheffer R,Jaffe J,Rahmani S,Leshem E,Valinsky L

    更新日期:2018-02-01 00:00:00

  • Maternal antibody to hepatitis B core antigen detected in dried neonatal blood spot samples.

    abstract::Despite Department of Health recommendations, universal antenatal testing for hepatitis B virus (HBV) is not performed throughout Scotland. We describe the evaluation of an assay to document past or present infection with HBV, by identifying maternal antibody in routine Guthrie dried neonatal blood spot samples taken ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268898001393

    authors: Tappin DM,Greer K,Cameron S,Kennedy R,Brown AJ,Girdwood RW

    更新日期:1998-10-01 00:00:00

  • Epidemiological features of Mediterranean spotted fever, murine typhus, and Q fever in Split-Dalmatia County (Croatia), 1982-2002.

    abstract::We determined the epidemiological features of three zoonoses in hospitalized patients in southern Croatia. Patients were diagnosed by serological testing. Clinical and epidemiological data were also collected. Between 1982 and 2002, Mediterranean spotted fever (MSF) was diagnosed in 126 (incidence rate 1.27/100,000 pe...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268807009491

    authors: Punda-Polić V,Luksić B,Capkun V

    更新日期:2008-07-01 00:00:00

  • Length of stay an important mediator of hospital-acquired methicillin-resistant Staphylococcus aureus.

    abstract::Hospital-acquired methicillin-resistant Staphylococcus aureus (HA-MRSA) is becoming increasingly established in Asian hospitals. The primary aim of this study was to decompose the risk factors for HA-MRSA based on conceptual clinical pathways. The secondary aim was to show the amount of effect attributable to antibiot...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268815002733

    authors: Wong JG,Chen MI,Win MK,Ng PY,Chow A

    更新日期:2016-04-01 00:00:00

  • Pandemic A(H1N1) 2009 influenza: review of the Southern Hemisphere experience.

    abstract::We sought to systematically review the published literature describing the epidemiological aspects of the first wave of pandemic A(H1N1) 2009 influenza in the Southern Hemisphere. Fifteen studies were included in this review, originating from South America, Australia or New Zealand, and Africa. Across the different st...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,评审

    doi:10.1017/S0950268810002037

    authors: Falagas ME,Koletsi PK,Baskouta E,Rafailidis PI,Dimopoulos G,Karageorgopoulos DE

    更新日期:2011-01-01 00:00:00

  • Patient and strain characteristics in relation to the outcome of meningococcal disease: a multivariate analysis.

    abstract::To investigate the joint association of patient and strain characteristics with the outcome of meningococcal disease (MD), data were collected on 563 consecutive cases of MD reported between 1989 and 1990 in The Netherlands. The meningococcal isolates were characterized with regard to their surface characteristics. Se...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800057472

    authors: Scholten RJ,Bijlmer HA,Valkenburg HA,Dankert J

    更新日期:1994-02-01 00:00:00

  • The epidemiology of hepatitis A in Rio de Janeiro: environmental and domestic risk factors.

    abstract::A serological study of hepatitis A was carried out in low-income areas scheduled for a major sanitation programme in Rio de Janeiro, Brazil. Blood spots were collected by finger puncture and transported on filter paper, and total antibodies to hepatitis A virus were detected by ELISA. Households were also interviewed ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268801005945

    authors: Almeida LM,Werneck GL,Cairncross S,Coeli CM,Costa MC,Coletty PE

    更新日期:2001-10-01 00:00:00

  • Clostridium difficile infection in patients with haematological malignant disease. Risk factors, faecal toxins and pathogenic strains.

    abstract::Two hundred and forty-eight patients from shared oncology and general medical wards were prospectively studied over a 6-month period for carriage of Clostridium difficile during an outbreak of clinical disease with an epidemic strain of the organism. Risk factors for infection were assessed. Acute leukaemia and/or its...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800065560

    authors: Heard SR,Wren B,Barnett MJ,Thomas JM,Tabaqchali S

    更新日期:1988-02-01 00:00:00

  • Measles, mumps, rubella and VZV: importance of serological testing of vaccine-preventable diseases in young adults living with HIV in Germany.

    abstract::Measles, mumps, rubella (MMR) and varicella zoster virus (VZV) infection can cause serious diseases and complications in the HIV-positive population. Due to successful vaccination programmes measles, mumps and congenital rubella syndrome has become neglected in Germany. However, recent outbreaks of measles have occurr...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,多中心研究

    doi:10.1017/S095026881600217X

    authors: Schwarze-Zander C,Draenert R,Lehmann C,Stecher M,Boesecke C,Sammet S,Wasmuth JC,Seybold U,Gillor D,Wieland U,Kümmerle T,Strassburg CP,Mankertz A,Eis-Hübinger AM,Jäger G,Fätkenheuer G,Bogner JR,Rockstroh JK,Vehreschild

    更新日期:2017-01-01 00:00:00

  • Improved hepatitis C treatment response in younger patients: findings from the UK HCV National Register cohort study.

    abstract::In a cohort of 272 treatment-naive individuals with chronic hepatitis C infection acquired on a known date who were enrolled in the UK HCV National Register, a progressive improvement in response to treatment was found with the evolution of antiviral therapies from 20% (25/122) for interferon monotherapy to 63% (55/88...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268811002317

    authors: Harris HE,Costella A,Amirthalingam G,Alexander G,Ramsay ME,Andrews N,UK HCV National Register Collaborators.,UK HCV National Register Steering Group.

    更新日期:2012-10-01 00:00:00

  • Risk factors for gastroenteritis: a nested case-control study.

    abstract::This nested case-control study investigated the risk factors for gastroenteritis in a cohort using rainwater as their primary domestic water source. Consumption of beef [odds ratio (OR) 2·74, 95% confidence interval (CI) 1·56-4·80], handling of raw fresh chicken in the household (OR 1·52, 95% CI 1·02-2·29) and animal ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268810001159

    authors: Rodrigo S,Sinclair M,Wolfe R,Leder K

    更新日期:2011-04-01 00:00:00

  • Source attribution of human campylobacteriosis in Denmark.

    abstract::SUMMARY This study assesses the contribution of different sources of human campylobacteriosis in Denmark using two different source-attribution approaches. In total, 794 non-human isolates and 406 isolates from human cases (domestic, travel related, and cases with unknown travel history) were collected. Isolates were ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268813002719

    authors: Boysen L,Rosenquist H,Larsson JT,Nielsen EM,Sørensen G,Nordentoft S,Hald T

    更新日期:2014-08-01 00:00:00

  • Molecular epidemiology of norovirus strains circulating in Ireland from 2003 to 2004.

    abstract::Since 2002, the burden of norovirus (NoV) infection in Ireland has increased. Outbreaks in institutional settings are the most common causing widespread disruption to health service delivery. This is the first national study of NoV in the Republic of Ireland and its aim was to identify the major NoV strains circulatin...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268806006121

    authors: Waters A,Coughlan S,Dunford L,Hall WW

    更新日期:2006-10-01 00:00:00

  • The prevalence of antimicrobial resistance in human faecal flora in South Africa.

    abstract::Between January and March 1992, 361 faecal specimens were collected from the healthy black population in the Transvaal Province of South Africa. Each specimen was examined for the prevalence of antimicrobial resistance in commensal bacteria. Volunteers, from both rural and urban dwellings, were divided into four age g...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800056922

    authors: Shanahan PM,Wylie BA,Adrian PV,Koornhof HJ,Thomson CJ,Amyes SG

    更新日期:1993-10-01 00:00:00

  • Early-life environment influencing susceptibility to cytomegalovirus infection: evidence from the Leiden Longevity Study and the Longitudinal Study of Aging Danish Twins.

    abstract::Human cytomegalovirus (CMV) is a common herpesvirus establishing lifelong persisting infection, which has been implicated in immunosenescence and mortality in the elderly. Little is known about how and when susceptibility to CMV infection is determined. We measured CMV seroprevalence in two genetically informative coh...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268811001397

    authors: Mortensen LH,Maier AB,Slagbom PE,Pawelec G,Derhovanessian E,Petersen I,Jahn G,Westendorp RG,Christensen K

    更新日期:2012-05-01 00:00:00

  • The effectiveness of Haemophilus influenzae type b conjugate vaccines in a high risk population measured using immunization register data.

    abstract::The Northern Territory of Australia has had historically very high incidence rates of invasive Haemophilus influenzae type b disease in children less than 5 years of age, with the burden of disease greatest among Aboriginal infants less than 12 months. This study documents the impact of conjugate Hib vaccines introduc...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268801005155

    authors: Markey P,Krause V,Boslego JW,Coplan PM,Dargan JM,Kaplan KM

    更新日期:2001-02-01 00:00:00

  • The prevalence and the risk behaviours associated with the transmission of hepatitis C virus in Australian correctional facilities.

    abstract::This study measured the prevalence and the risk factors associated with HCV antibody-positive prisoners. A total of 630 prisoners completed a questionnaire about risk behaviours associated with HCV transmission and were tested for HCV antibody from a blood test. Of these 362 (57.5%) prisoners were HCV antibody positiv...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268803001882

    authors: Hellard ME,Hocking JS,Crofts N

    更新日期:2004-06-01 00:00:00

  • Animal agriculture exposures among Minnesota residents with zoonotic enteric infections, 2012-2016.

    abstract::Prospective, population-based surveillance to systematically ascertain exposures to food production animals or their environments among Minnesota residents with sporadic, domestically acquired, laboratory-confirmed enteric zoonotic pathogen infections was conducted from 2012 through 2016. Twenty-three percent (n = 170...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268819002309

    authors: Klumb CA,Scheftel JM,Smith KE

    更新日期:2020-03-16 00:00:00

  • An outbreak of hepatitis A in Gloucester, UK.

    abstract::During an outbreak of hepatitis A that occurred in Gloucester, UK between September 1989 and January 1991, 162 clinical cases were identified through notifications and laboratory reports, a monthly attack rate of 1.05 per 10,000 residents. The highest attack rate was seen in 5-14-year-olds. There were significant corr...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:

    authors: Majeed FA,Stuart JM,Cartwright KA,Room R,Gilkes JR,Smith MC,Watson BE

    更新日期:1992-08-01 00:00:00

  • Genotyping of hepatitis C virus isolates from Basque Country, Spain.

    abstract::The genotype of HCV was determined in 161 chronic HCV-infected patients. The patients were classified into three groups on the basis of the origin of the HCV infection: 50 patients had a history of intravenous drug use (IVDU) but no HIV infection; 41 patients had received blood transfusions, and 70 patients had no kno...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800059227

    authors: Cilla G,García-Bengoechea M,Perez-Trallero E,Montalvo I,Vicente D,Arenas JI

    更新日期:1996-12-01 00:00:00

  • A multi-centre prospective case-control study of campylobacter infection in persons aged 5 years and older in Australia.

    abstract::There are an estimated 277,000 cases of campylobacteriosis in Australia each year, most of which are thought to be sporadically acquired. To explore causes for these infections, we conducted a multi-centre case-control study of patients and community controls across five Australian States during 2001-2002. A total of ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,多中心研究

    doi:10.1017/S0950268806007576

    authors: Stafford RJ,Schluter P,Kirk M,Wilson A,Unicomb L,Ashbolt R,Gregory J,OzFoodNet Working Group.

    更新日期:2007-08-01 00:00:00

  • The first study on opportunistic intestinal microsporidiosis in IBD patients receiving immunosuppressive medications in Iran.

    abstract::Microsporida are known as opportunistic unicellular organisms and have recently been reclassified as fungi that have been frequently reported from patients with congenital and acquired immunity failure disorders, worldwide. However, use of immunosuppressive medications in inflammatory bowel disease (IBD) patients sign...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268817000954

    authors: Hasani Z,Aghdaei HA,Balaii H,Azimirad M,Mirsamadi ES,Mirjalali H,Zali MR

    更新日期:2017-07-01 00:00:00

  • Risk factors for and influence of bloodstream infections on mortality: a 1-year prospective study in a Greek intensive-care unit.

    abstract::To determine the incidence, risk factors for, and the influence of bloodstream infections (BSIs) on mortality of patients in intensive-care units (ICUs), prospectively collected data from all patients with a stay in an ICU >48 h, during a 1-year period, were analysed. Of 572 patients, 148 developed a total of 232 BSI ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268808001271

    authors: Pratikaki M,Platsouka E,Sotiropoulou C,Vassilakopoulos T,Paniara O,Roussos C,Routsi C

    更新日期:2009-05-01 00:00:00

  • A continuing high incidence of subacute sclerosing panencephalitis (SSPE) in the Eastern Highlands of Papua New Guinea.

    abstract::The aims of this descriptive study were to confirm the high incidence of subacute sclerosing panencephalitis (SSPE) previously reported from Papua New Guinea (PNG) and to relate SSPE to previous measles vaccination and measles illness. From February 1997 to April 1999 we diagnosed a total of 55 patients with SSPE at G...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268803008999

    authors: Takasu T,Mgone JM,Mgone CS,Miki K,Komase K,Namae H,Saito Y,Kokubun Y,Nishimura T,Kawanishi R,Mizutani T,Markus TJ,Kono J,Asuo PG,Alpers MP

    更新日期:2003-10-01 00:00:00

  • Molecular variation of meningococcal serotype 4 antigen genes.

    abstract::Changes in the frequency of serogroup B non serotypable (B:NT) meningococci isolated in England and Wales were investigated by T-track fingerprint analysis, DNA nucleotide sequence determination, and serotyping by whole cell ELISA and dot blot assay. Seventy-three per cent of the isolates designated as B:NT by the Men...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268898008942

    authors: Urwin R,Feavers IM,Jones DM,Maiden MC,Fox AJ

    更新日期:1998-08-01 00:00:00

  • Hepatitis B vaccination for healthcare personnel in American Samoa: pre-implementation survey for policy decision.

    abstract::American Samoa does not have a hepatitis B vaccination policy for healthcare personnel (HCP). Consequently, hepatitis B has remained a health threat to HCP. In this study, we performed a cross-sectional study and examined demographic and risk information and hepatitis B vaccination, testing, and serostatus in hospital...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268813003506

    authors: Ly KN,Roberts H,Williams RE,Masunu-Faleafaga Y,Drobeniuc J,Kamili S,Teshale EH

    更新日期:2014-12-01 00:00:00

  • The effect of vaccination on undetected persistence of foot-and-mouth disease virus in cattle herds and sheep flocks.

    abstract::The importance of carrier animals (those in whom virus persists after recovery from disease or acute infection) and their potential role in the spread of disease remain open questions within foot-and-mouth disease epidemiology. Using simple probabilistic models we attempt to quantify the effect of emergency vaccinatio...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268809002349

    authors: Schley D,Paton DJ,Cox SJ,Parida S,Gubbins S

    更新日期:2009-10-01 00:00:00

  • Age, influenza pandemics and disease dynamics.

    abstract::The world is currently confronting the first influenza pandemic of the 21st century [caused by a novel pandemic influenza A (H1N1) virus]. Earlier pandemics have been characterized by age distributions that are distinct from those observed with seasonal influenza epidemics, with higher attack rates (and correspondingl...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268810000579

    authors: Greer AL,Tuite A,Fisman DN

    更新日期:2010-11-01 00:00:00