Comparison of different vaccines and induced immune response against Campylobacter jejuni colonization in the infant mouse.

Abstract:

:The degree of protection conferred by vaccinated dams on infant mice against colonization by Campylobacter jejuni depended on the bacterial strain, preparation, and route of administration of the vaccine. In some instances of homologous protection, serum bactericidal titres correlated well with protection. However, boiled C. jejuni vaccine, which was non-protective, also elicited a strong bactericidal antibody response. Conversely, bactericidal activity could not be demonstrated against strains capable of cross-protection. There was a good correlation between high campylobacter-specific IgG response and bactericidal activity.

journal_name

Epidemiol Infect

authors

Abimiku AG,Dolby JM,Borriello SP

doi

10.1017/s0950268800029940

subject

Has Abstract

pub_date

1989-04-01 00:00:00

pages

271-80

issue

2

eissn

0950-2688

issn

1469-4409

journal_volume

102

pub_type

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