Distribution of the meningococcal insertion sequence IS1301 in clonal lineages of Neisseria meningitidis.

Abstract:

:The distribution of the meningococcal insertion sequence IS1301 was analysed in 496 strains of different serogroups and clonal lineages of Neisseria meningitidis, and in 64 neisserial strains other than N. meningitidis. IS1301 was found in meningococci, but not in apathogenic Neisseria sp. and Neisseria gonorrhoeae. The copy numbers of IS1301 varied between 2 and 17 per genome. IS1301 positive strains were mostly found among the serogroups 29E, W135, X, and Y. Clonal lineages of serogroup A, B, and C meningococci associated with epidemic meningococcal disease were rarely positive for IS1301.

journal_name

Epidemiol Infect

authors

Hilse R,Stoevesandt J,Caugant DA,Claus H,Frosch M,Vogel U

doi

10.1017/s0950268899003647

subject

Has Abstract

pub_date

2000-04-01 00:00:00

pages

337-40

issue

2

eissn

0950-2688

issn

1469-4409

journal_volume

124

pub_type

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