Abstract:
:Transmission of acute respiratory infections (ARI) and acute gastroenteritis (AGE) often occurs in households. The aim of this study was to assess which proportion of ARI and AGE is introduced and transmitted by children in German households with children attending child care. We recruited families with children aged 0-6 years in Braunschweig (Germany), for a 4 months prospective cohort study in the winter period 2014/2015. Every household member was included in a health diary and used nasal swabs for pathogen identification in case of ARI. We defined a transmission if two persons had overlapping periods with symptoms and used additional definitions for sensitivity analyses. In total, 77 households participated with 282 persons. We observed 277 transmission events for ARI and 23 for AGE. In most cases, the first infected person in a household was a child (ARI: 63%, AGE: 53%), and the risk of within-household transmission was two times higher when the index case was a child. In 26 ARI-transmission events, pathogens were detected for both cases; hereof in 35% (95% confidence interval (17-56%)) the pathogens were different. Thus, symptomatic infections in household members, apparently linked in time, were in 2/3 associated with the same pathogens.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Schlinkmann KM,Bakuli A,Karch A,Meyer F,Dreesman J,Monazahian M,Mikolajczyk Rdoi
10.1017/S0950268818000316subject
Has Abstractpub_date
2018-04-01 00:00:00pages
627-632issue
5eissn
0950-2688issn
1469-4409pii
S0950268818000316journal_volume
146pub_type
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