Assessment of neonatal tetanus elimination in an African setting by lot quality assurance cluster sampling (LQA-CS).

Abstract:

:Neonatal tetanus (NT) elimination, < 1 case per 1,000 live births (LB), was assessed at district level in Zimbabwe using a combined lot quality assurance-cluster sampling survey (LQA-CS). Three of the highest risk districts were selected. NT was considered eliminated if fewer than a specified number of NT deaths (proxy for NT cases) were found in the sample determined using operating characteristic curves and tables. TT2 + vaccine coverage was measured in mothers who gave birth 1-13 months before the survey and women aged 15-49 years. NT was considered as eliminated, TT2+ coverage was 78% (95% CI 71-82%) in women aged 15-49 and 83% (95% CI 76-89%) in mothers. The survey cost 30,000 US dollars excluding costs of consultants. NT incidence was below the elimination threshold (< 1/1,000 LB) in the surveyed districts and probably in all districts. LQA-CS is a practical, relatively cost effective field method which can be applied in an African setting to assess NT elimination status.

journal_name

Epidemiol Infect

authors

Cotter B,Bremer V,Stroh G,Msambichaka K,Mabuzane E,Munyoro M,Shirehwa F,Biellik R,Birmingham M

doi

10.1017/s0950268802008233

subject

Has Abstract

pub_date

2003-04-01 00:00:00

pages

221-6

issue

2

eissn

0950-2688

issn

1469-4409

journal_volume

130

pub_type

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