Emergence of MRSA clone ST22 in healthy young adults in the community in the absence of risk factors.

Abstract:

:One thousand adults aged between 18 and 35 years were investigated for nasal colonization with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA). Each volunteer completed a questionnaire to assess the presence or absence of risk factors for hospital-acquired MRSA (HA-MRSA) carriage. All MRSA isolated were characterized by microbiological and molecular methods. A S. aureus carriage rate of 22% and a MRSA carriage rate of 0.7% were observed. Analysis of the questionnaires revealed 121 individuals with HA-MRSA risk factors. Subsequently two MRSA infections with associated risk factors were excluded from calculation of the true carriage rate and an adjusted rate of 0.57% (5/879) was established. All seven MRSA isolates expressed the genotypic profile ST22-MRSA-IV, were PVL negative, agr type 1, and differed only by their antimicrobial susceptibility patterns. ST22-MRSA-IV (EMRSA-15) has shown worldwide spread in the hospital setting but has not been previously documented in isolation in the community.

journal_name

Epidemiol Infect

authors

Mollaghan AM,Lucey B,Coffey A,Cotter L

doi

10.1017/S0950268810000191

subject

Has Abstract

pub_date

2010-05-01 00:00:00

pages

673-6

issue

5

eissn

0950-2688

issn

1469-4409

pii

S0950268810000191

journal_volume

138

pub_type

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