Trends in HCV prevalence, risk factors and distribution of viral genotypes in injecting drug users: findings from two cross-sectional studies.

Abstract:

:In the last decade, a declining prevalence of HCV infection has been described in injecting drug users (IDUs) in different countries. This study is the first to assess temporal trends in drug-injecting patterns, HCV infection rates and viral genotype distribution in 770 Brazilian IDUs, recruited by two cross-sectional studies (1994-1997 and 1999-2001). A substantial decline in the prevalence of HCV infection was found over the years (75% in 1994 vs. 20.6% in 2001, P<0.001) that may be a consequence of the significant reduction in the overall frequencies of drug injection and needle-sharing, as well as the participation of IDUs in initiatives aimed at reducing drug-related harm. No trend was found in terms of viral genotype distribution. Despite the favourable scenario, preventive measures must be maintained, especially in vulnerable subgroups such as young or new injectors, where risky behaviours through direct and indirect sharing practices remain common.

journal_name

Epidemiol Infect

authors

Oliveira ML,Yoshida CF,Telles PR,Hacker MA,Oliveira SA,Miguel JC,do O KM,Bastos FI

doi

10.1017/S0950268808001970

subject

Has Abstract

pub_date

2009-07-01 00:00:00

pages

970-9

issue

7

eissn

0950-2688

issn

1469-4409

pii

S0950268808001970

journal_volume

137

pub_type

杂志文章
  • Evaluation of the limiting antigen avidity EIA (LAg) in people who inject drugs in Greece.

    abstract::This analysis assessed the utility of the limiting antigen avidity assay (LAg). Samples of people who inject drugs (PWID) in Greece with documented duration of HIV-1 infection were tested by LAg. A LAg-normalized optical density (ODn) ⩽1·5 corresponds to a recency window period of 130 days. The proportion true recent ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268816002417

    authors: Nikolopoulos GK,Katsoulidou A,Kantzanou M,Rokka C,Tsiara C,Sypsa V,Paraskevis D,Psichogiou M,Friedman S,Hatzakis A

    更新日期:2017-01-01 00:00:00

  • Prevalence of and risk factors for MRSA carriage in companion animals: a survey of dogs, cats and horses.

    abstract::We investigated the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) carriage in a convenience sample of purposely selected populations of dogs, cats and horses in the Greater London area. Swabs from carriage sites were pooled, enriched and processed by standard bacteriological methods. The presence of...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026881000227X

    authors: Loeffler A,Pfeiffer DU,Lindsay JA,Soares Magalhães RJ,Lloyd DH

    更新日期:2011-07-01 00:00:00

  • Gastroenteritis associated with accidental contamination of drinking water with partially treated water.

    abstract::Due to human error, drinking water supplied to a new housing estate in The Netherlands was contaminated with grey water. The cohort of 921 accidentally exposed households (area A) had a higher attack rate for diarrhoea (54.1%) than a non-exposed cohort of 1529 households from an adjacent area (B) (24%) (RR 2.3, 95% CI...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268806007497

    authors: Fernandes TM,Schout C,De Roda Husman AM,Eilander A,Vennema H,van Duynhoven YT

    更新日期:2007-07-01 00:00:00

  • Signs and symptoms in common colds.

    abstract::The patterns of disease caused by five common viruses which infect the respiratory tract are described. The viruses were strains of rhinovirus types 2, 9, and 14, a strain of coronavirus type 229E and of respiratory syncytial virus. Volunteers were given nasal drops containing a low infectious dose of one of the virus...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800056764

    authors: Tyrrell DA,Cohen S,Schlarb JE

    更新日期:1993-08-01 00:00:00

  • Hospitalization rates associated with hepatitis B and HIV co-infection, age and sex in a population-based cohort of people diagnosed with hepatitis C.

    abstract::To determine the extent age, sex and co-infection affect morbidity in people infected with hepatitis C virus (HCV), we performed a population-based study linking HCV notifications in New South Wales, Australia with their hospital (July 2000 to June 2006), hepatitis B virus (HBV) and HIV notification, and death records...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026881000258X

    authors: Gidding HF,Amin J,Dore GJ,Law MG

    更新日期:2011-08-01 00:00:00

  • Risk factors for hospital-acquired methicillin-resistant Staphylococcus aureus bacteraemia: a case-control study.

    abstract::A case-control study was undertaken in an acute district general hospital to identify risk factors for hospital-acquired bacteraemia caused by methicillin-resistant Staphylococcus aureus (MRSA). Cases of hospital-acquired MRSA bacteraemia were defined as consecutive patients from whom MRSA was isolated from a blood sa...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0950268806006327

    authors: Carnicer-Pont D,Bailey KA,Mason BW,Walker AM,Evans MR,Salmon RL

    更新日期:2006-12-01 00:00:00

  • Serological diagnosis of leishmaniasis: on detecting infection as well as disease.

    abstract::Serological tests are very frequently used in epidemiological surveys of leishmaniasis and other parasitoses. Their sensitivity and specificity are generally defined with respect to parasitism and disease, rather than infection. The reason is that known positives are those individuals most likely to yield parasites, o...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800051074

    authors: Dye C,Vidor E,Dereure J

    更新日期:1993-06-01 00:00:00

  • Trimethoprim resistance in commensal bacteria isolated from farm animals.

    abstract::Trimethoprim resistance was examined in faecal bacteria obtained from chickens, sheep, cattle and pigs. The incidence of trimethoprim resistance in porcine strains was 17% (157/922) and, whereas 15.8% (146/922) of these bacteria were highly resistant, only 4% (37/922) of the isolates possessed trimethoprim resistance ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800061744

    authors: Amyes SG

    更新日期:1987-02-01 00:00:00

  • A longitudinal household study of Streptococcus pneumoniae nasopharyngeal carriage in a UK setting.

    abstract::A 10-month longitudinal household study of pre-school children and their families was undertaken with monthly visits collecting epidemiological data and nasopharyngeal swabs in Hertfordshire, England from 2001 to 2002. Pneumococcal culture was with standard methods. In total, 121 families (489 individuals) took part. ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268805004012

    authors: Hussain M,Melegaro A,Pebody RG,George R,Edmunds WJ,Talukdar R,Martin SA,Efstratiou A,Miller E

    更新日期:2005-10-01 00:00:00

  • Q fever infection in dairy cattle herds: increased risk with high wind speed and low precipitation.

    abstract::Ruminants are considered the main reservoir for transmission of Coxiella burnetii (Cb) to humans. The implementation of effective control measures against Cb in ruminants requires knowledge about potential risk factors. The objectives of this study were (i) to describe the spatial distribution of Q fever-infected dair...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814003926

    authors: Nusinovici S,Frössling J,Widgren S,Beaudeau F,Lindberg A

    更新日期:2015-11-01 00:00:00

  • Phylogenetic and antigenic analysis of influenza A(H3N2) viruses isolated from conscripts receiving influenza vaccine prior to the epidemic season of 1998/9.

    abstract::Roughly half (54%) of the 910 young conscripts at a garrison in Finland were vaccinated with commercial influenza vaccines in autumn 1998. During the influenza outbreak in February 1999, 12 H3N2-subtype virus strains were isolated from vaccinated patients, and 11 such strains were isolated from unvaccinated patients. ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268802007410

    authors: Pyhälä R,Ikonen N,Haanpää M,Santanen R,Tervahauta R

    更新日期:2002-10-01 00:00:00

  • A case-control study on the occurrence of Salmonella spp. in the environment of pigs.

    abstract::The objective of this study was to compare the occurrence of Salmonella spp. found in the animal environment in pig herds with different Salmonella risks (61 herds with low seroprevalence, 81 herds with high seroprevalence) on a broad scale. The environmental samples were divided into two types: direct (n=1105) and in...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268811000239

    authors: Gotter V,Blaha T,Klein G

    更新日期:2012-01-01 00:00:00

  • Antibiotic prescriptions and cycles of Mycoplasma pneumoniae infections in Norway: can a nationwide prescription register be used for surveillance?

    abstract::Mycoplasma pneumoniae outbreaks cause increased use of macrolides and tetracyclines. We aimed to investigate whether drug use data, in addition to laboratory data, could improve understanding of the spread of M. pneumoniae epidemics. Number of users of Mycoplasma antibiotics (erythromycin, doxycycline, clarithromycin)...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814002908

    authors: Blix HS,Vestrheim DF,Hjellvik V,Skaare D,Christensen A,Steinbakk M

    更新日期:2015-07-01 00:00:00

  • Assessment of areas at increased risk for poliovirus circulation in Ecuador.

    abstract::To assess areas at risk for poliovirus circulation in Ecuador, we first selected provinces at highest risk based on low immunization coverage with three doses of oral poliovirus vaccine, and a low number of reported cases of acute flaccid paralysis (AFP). Subsequently, we reviewed discharge data for the period 1996--2...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,多中心研究

    doi:10.1017/s0950268804002626

    authors: Dayan GH,Rodríguez R,Vinjé J,Vásconez N,Cáceres V,Gregoricus N,Sobsey M,Landaverde M

    更新日期:2004-10-01 00:00:00

  • Assessing the impact of a nurse-delivered home dried blood spot service on uptake of testing for household contacts of hepatitis B-infected pregnant women across two London trusts.

    abstract::Despite national guidance recommending testing and vaccination of household contacts of hepatitis B-infected pregnant women, provision and uptake of this is sub-optimal. The aim of this study was to evaluate the use of in-home dried blood spot (DBS) testing to increase testing and vaccination of household contacts of ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268815003325

    authors: Keel P,Edwards G,Flood J,Nixon G,Beebeejaun K,Shute J,Poh J,Millar A,Ijaz S,Parry J,Mandal S,Ramsay M,Amirthalingam G

    更新日期:2016-07-01 00:00:00

  • Epidemiology and factors associated with candidaemia following Clostridium difficile infection in adults within metropolitan Atlanta, 2009-2013.

    abstract::We assessed prevalence of and risk factors for candidaemia following Clostridium difficile infection (CDI) using longitudinal population-based surveillance. Of 13 615 adults with CDI, 113 (0·8%) developed candidaemia in the 120 days following CDI. In a matched case-control analysis, severe CDI and CDI treatment with v...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268815003027

    authors: Vallabhaneni S,Almendares O,Farley MM,Reno J,Smith ZT,Stein B,Magill SS,Smith RM,Cleveland AA,Lessa FC

    更新日期:2016-05-01 00:00:00

  • Are food exposures obtained through commercial market panels representative of the general population? Implications for outbreak investigations.

    abstract::Current methods of control recruitment for case-control studies can be slow (a particular issue for outbreak investigations), resource-intensive and subject to a range of biases. Commercial market panels are a potential source of rapidly recruited controls. Our study evaluated food exposure data from these panel contr...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268819000219

    authors: Inns T,Curtis D,Crook P,Vivancos R,Gardiner D,McCarthy N,Mook P

    更新日期:2019-01-01 00:00:00

  • Association between meteorological factors and reported cases of hand, foot, and mouth disease from 2000 to 2015 in Japan.

    abstract::The purpose of this study was to clarify the association between hand, foot, and mouth disease (HFMD) epidemics and meteorological conditions. We used HFMD surveillance data of all 47 prefectures in Japan from January 2000 to December 2015. Spectral analysis was performed using the maximum entropy method (MEM) for tem...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268817001820

    authors: Sumi A,Toyoda S,Kanou K,Fujimoto T,Mise K,Kohei Y,Koyama A,Kobayashi N

    更新日期:2017-10-01 00:00:00

  • Full-genome sequence analysis of an uncommon norovirus genotype, GII.21, from South Korea.

    abstract::Noroviruses (NoVs) are major causal agents of acute gastroenteritis in humans. NoV GII.4 is the predominant genotype globally. However, uncommon and minor types of NoVs are consistently detected and some have been shown to dominate over GII.4. Therefore, the prevalence of dominant and uncommon NoVs makes the identific...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268817001273

    authors: Lee JW,Lee SG,Cho HG,Park YJ,Yun JW,Park CJ,Paik SY

    更新日期:2017-08-01 00:00:00

  • Characterization of a new genotype of measles virus detected in China and England.

    abstract::We report the co-circulation of a new lineage of measles virus (MV) and an Edmonston-like (Ed-like) genotype of MV in China during 1995-7. Sequence analysis of 25 strains was performed on a 282 nucleotides (nt) region of the nucleoprotein (N) gene, a 450-nt region of the haemagglutinin (H) gene and a 152-nt region of ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268898001666

    authors: Jin L,Sun YJ,Ge L,Brown DW

    更新日期:1998-12-01 00:00:00

  • Long-term impact of vaccination on Haemophilus influenzae type b (Hib) carriage in the United Kingdom.

    abstract::A recent resurgence in serious infections due to Haemophilus influenzae type b (Hib) has been observed in the United Kingdom. More information on Hib transmission in the population is required in order to better understand the mechanism of this increase. The Public Health Laboratory Service (subsumed into the Health P...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268804002122

    authors: McVernon J,Howard AJ,Slack MP,Ramsay ME

    更新日期:2004-08-01 00:00:00

  • HBV and HCV infection among non-European Union immigrants in North-East Italy.

    abstract::The status of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection among non-European Union (non-EU) immigrants in North-East Italy was evaluated. Among the 1683 individuals tested the prevalence of HBsAg was 8.9% (150 subjects) and of HBV antibodies (anti-HBc with/without anti-HBs) was 38.9% (654 subjects). ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268898001034

    authors: Chiaramonte M,Pupo A,Menegon T,Baldo V,Malatesta R,Trivello R

    更新日期:1998-08-01 00:00:00

  • Environmental risk factors of West Nile virus infection of horses in the Senegal River basin.

    abstract::In 2005, a serological study was carried out on horses in five ecologically contrasted zones of the Senegal River basin (Senegal) to assess West Nile virus (WNV) transmission and investigate underlying environmental risk factors. In each study zone, horses were randomly selected and blood samples taken. A land-cover m...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026881000035X

    authors: Chevalier V,Dupressoir A,Tran A,Diop OM,Gottland C,Diallo M,Etter E,Ndiaye M,Grosbois V,Dia M,Gaidet N,Sall AA,Soti V,Niang M

    更新日期:2010-11-01 00:00:00

  • Interpretation of band differences to distinguish strains of Serratia marcescens by pulsed-field gel electrophoresis of XbaI DNA digests.

    abstract::The number of band differences in DNA macrorestriction profiles required to distinguish unrelated strains from an index strain varies in an outbreak with the species and restriction enzyme used. In order to define this difference for epidemiological studies of Serratia marcescens, we produced DNA fingerprints from 57 ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268899004112

    authors: Aucken HM,Boquete T,Kaufmann ME,Pitt TL

    更新日期:2000-08-01 00:00:00

  • Surgical site infection following cesarean section in a general hospital in Kuwait: trends and risk factors.

    abstract::Surgical site infections (SSI) are a significant cause of post-surgical morbidity and mortality. The objectives of this study were to determine the prevalence of SSI and identify risk factors for infections following cesarean section (CS). A prospective study of SSI after CS was carried out from January 2014 to Decemb...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268819001675

    authors: Alfouzan W,Al Fadhli M,Abdo N,Alali W,Dhar R

    更新日期:2019-10-10 00:00:00

  • Protecting the vaccinating population in the face of a measles epidemic: assessing the impact of adjusted vaccination schedules.

    abstract::We investigated which vaccination schedule gives best protection to the vaccinating population, in case there is a measles epidemic in an area with low vaccine coverage. We considered combinations of an early measles vaccination (none, at 6 months or at 9 months), a measles-mumps-rubella (MMR) vaccination around the f...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268801006409

    authors: van den Hof S,Wallinga J,Widdowson MA,Conyn-van Spaendonck MA

    更新日期:2002-02-01 00:00:00

  • Influenza vaccine failure in the tropics: a retrospective cohort study of waning effectiveness.

    abstract::Influenza vaccine effectiveness (VE) wanes over the course of a temperate climate winter season but little data are available from tropical countries with year-round influenza virus activity. In Singapore, a retrospective cohort study of adults vaccinated from 2013 to 2017 was conducted. Influenza vaccine failure was ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268820002952

    authors: Young BE,Mak TM,Ang LW,Sadarangani S,Ho HJ,Wilder-Smith A,Barkham T,Chen M

    更新日期:2020-12-02 00:00:00

  • Descriptive epidemiology of coronavirus disease 2019 in Nigeria, 27 February-6 June 2020.

    abstract::The objective of this study was to describe the epidemiology of COVID-19 in Nigeria with a view of generating evidence to enhance planning and response strategies. A national surveillance dataset between 27 February and 6 June 2020 was retrospectively analysed, with confirmatory testing for COVID-19 done by real-time ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026882000206X

    authors: Elimian KO,Ochu CL,Ilori E,Oladejo J,Igumbor E,Steinhardt L,Wagai J,Arinze C,Ukponu W,Obiekea C,Aderinola O,Crawford E,Olayinka A,Dan-Nwafor C,Okwor T,Disu Y,Yinka-Ogunleye A,Kanu NE,Olawepo OA,Aruna O,Michael CA

    更新日期:2020-09-11 00:00:00

  • Attributing sporadic and outbreak-associated infections to sources: blending epidemiological data.

    abstract::Common sources of shiga toxin-producing Escherichia coli (STEC) O157 infection have been identified by investigating outbreaks and by case-control studies of sporadic infections. We conducted an analysis to attribute STEC O157 infections ascertained in 1996 and 1999 by the Foodborne Diseases Active Surveillance Networ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268813000915

    authors: Cole D,Griffin PM,Fullerton KE,Ayers T,Smith K,Ingram LA,Kissler B,Hoekstra RM

    更新日期:2014-02-01 00:00:00

  • What happened at Vienna's Allgemeines Krankenhaus after Semmelweis's contract as Assistant in the First Maternity Division was terminated?

    abstract::Ignác Fülöp Semmelweis is famous for dramatically reducing puerperal mortality while he was an Assistant in Vienna's largest hospital, the Allgemeines Krankenhaus; he did this, mainly, by requiring medical personnel to disinfect their hands by washing in a chlorine solution. But Semmelweis was soon removed from his po...

    journal_title:Epidemiology and infection

    pub_type: 传,历史文章,杂志文章

    doi:10.1017/S0950268817000875

    authors: Jadraque PP,Carter KC

    更新日期:2017-07-01 00:00:00