Abstract:
:In the last decade, a declining prevalence of HCV infection has been described in injecting drug users (IDUs) in different countries. This study is the first to assess temporal trends in drug-injecting patterns, HCV infection rates and viral genotype distribution in 770 Brazilian IDUs, recruited by two cross-sectional studies (1994-1997 and 1999-2001). A substantial decline in the prevalence of HCV infection was found over the years (75% in 1994 vs. 20.6% in 2001, P<0.001) that may be a consequence of the significant reduction in the overall frequencies of drug injection and needle-sharing, as well as the participation of IDUs in initiatives aimed at reducing drug-related harm. No trend was found in terms of viral genotype distribution. Despite the favourable scenario, preventive measures must be maintained, especially in vulnerable subgroups such as young or new injectors, where risky behaviours through direct and indirect sharing practices remain common.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Oliveira ML,Yoshida CF,Telles PR,Hacker MA,Oliveira SA,Miguel JC,do O KM,Bastos FIdoi
10.1017/S0950268808001970subject
Has Abstractpub_date
2009-07-01 00:00:00pages
970-9issue
7eissn
0950-2688issn
1469-4409pii
S0950268808001970journal_volume
137pub_type
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