Abstract:
:Plague, which is most often caused by the bite of Yersinia pestis-infected fleas, is a rapidly progressing, serious disease that can be fatal without prompt antibiotic treatment. In late December 2007, an outbreak of acute gastroenteritis occurred in Nimroz Province of southern Afghanistan. Of the 83 probable cases of illness, 17 died (case fatality 20·5%). Being a case was associated with consumption or handling of camel meat (adjusted odds ratio 4·4, 95% confidence interval 2·2-8·8, P<0·001). Molecular testing of patient clinical samples and of tissue from the camel using PCR/electrospray ionization-mass spectrometry revealed DNA signatures consistent with Yersinia pestis. Confirmatory testing using real-time PCR and immunological seroconversion of one of the patients confirmed that the outbreak was caused by plague, with a rare gastrointestinal presentation. The study highlights the challenges of identifying infectious agents in low-resource settings; it is the first reported occurrence of plague in Afghanistan.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Leslie T,Whitehouse CA,Yingst S,Baldwin C,Kakar F,Mofleh J,Hami AS,Mustafa L,Omar F,Ayazi E,Rossi C,Noormal B,Ziar N,Kakar Rdoi
10.1017/S0950268810001792subject
Has Abstractpub_date
2011-05-01 00:00:00pages
728-35issue
5eissn
0950-2688issn
1469-4409pii
S0950268810001792journal_volume
139pub_type
杂志文章abstract::Travel is a risk factor for Legionnaires' disease. In 2008, two cases were reported in condominium guests where we investigated a 2001 outbreak. We reinvestigated to identify additional cases and determine whether ongoing transmission resulted from persistent colonization of potable water. Exposures were assessed by m...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268811002779
更新日期:2012-11-01 00:00:00
abstract::There are an estimated 277,000 cases of campylobacteriosis in Australia each year, most of which are thought to be sporadically acquired. To explore causes for these infections, we conducted a multi-centre case-control study of patients and community controls across five Australian States during 2001-2002. A total of ...
journal_title:Epidemiology and infection
pub_type: 杂志文章,多中心研究
doi:10.1017/S0950268806007576
更新日期:2007-08-01 00:00:00
abstract::The distribution of Burkholderia pseudomallei was determined in soil collected from a rural district in Papua New Guinea (PNG) where melioidosis had recently been described, predominately affecting children. In 274 samples, 2.6% tested culture-positive for B. pseudomallei. Pulsed-field gel electrophoresis using SpeI d...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268807009429
更新日期:2008-07-01 00:00:00
abstract::False-positive serological reactions (FPSR) due to infections with Yersinia enterocolitica serotype Oratio9 (YeOratio9) are a problem in tests for brucellosis. In the present study, FPSR in classical and novel tests for brucellosis following experimental infections of pigs with YeOratio9 were compared with responses o...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S095026880500511X
更新日期:2006-04-01 00:00:00
abstract::We report a family cluster of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection involving five patients in a family cluster in Dazhou, China, including the epidemiological, clinical, laboratory and radiological findings. Three-generation transmission was observed. Through epidemiological investiga...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268820001521
更新日期:2020-07-07 00:00:00
abstract::During the period 1981-8 a clinical trial of a Q fever vaccine (Q-vax; Commonwealth Serum Laboratories, Melbourne) has been conducted in abattoir workers and other at-risk groups in South Australia. Volunteers in four abattoirs and visitors to the abattoirs were given one subcutaneous dose of 30 micrograms of a formal...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800059458
更新日期:1990-04-01 00:00:00
abstract::The clinical and microbiological characteristics of catheter-related bloodstream infection (CR-BSI) due to uncommon microorganisms was assessed in a retrospective case-control study over a 9-year period in a tertiary teaching hospital. Uncommon microorganisms were defined as those representing <0·5% of all CR-BSI. Dia...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268814001435
更新日期:2015-03-01 00:00:00
abstract::Escherichia coli O157 infections cause an estimated 60 deaths and 73 000 illnesses annually in the United States. A marked summer peak in incidence is largely unexplained. We investigated an outbreak of E. coli O157 infections at an agricultural fair in Ohio and implicated consumption of beverages made with fairground...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268803001237
更新日期:2003-12-01 00:00:00
abstract::The prevalence of antibodies to hepatitis A virus was assessed in a Dutch nationwide sample (n = 7367). A questionnaire was used to study the association with various sociodemographic characteristics. Overall, 33.8% (95% CI 31.6-36%) of the population had hepatitis A antibodies. The seroprevalence was less than 10% in...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268899003842
更新日期:2000-06-01 00:00:00
abstract::To determine if a prediction of epidemic cholera using climate data can be made, we performed autoregression analysis using the data recorded in Dhaka City, Bangladesh over a 20-year period (1983-2002) comparing the number of children aged <10 years who were infected with Vibrio cholerae O1 to the maximum and minimum ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268807008175
更新日期:2008-01-01 00:00:00
abstract::Annual overviews of waterborne disease outbreaks associated with untreated recreational water use provided by authorities responsible for bathing-water quality and public health in The Netherlands revealed 742 outbreaks during 1991-2007 mainly comprising of skin conditions (48%) and gastroenteritis (31%) and involving...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268810002347
更新日期:2011-07-01 00:00:00
abstract::This paper compares strains of foot-and-mouth disease (FMD) serotype SAT (South African Territories) 2 viruses isolated from Zimbabwe and other African countries using monoclonal antibodies (MAb). A sandwich-ELISA was used to examine the relative binding of anti-SAT 2 MAb to the various viruses. The MAb-binding profil...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s095026880005826x
更新日期:1995-08-01 00:00:00
abstract::Conditions and evidence continue to evolve related to the prediction of the prevalence of immunodeficiency-associated long-term vaccine-derived poliovirus (iVDPV) excreters, which affect assumptions related to forecasting risks and evaluating potential risk management options. Multiple recent reviews provided informat...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S095026881900181X
更新日期:2019-10-24 00:00:00
abstract::Using DNA probes specific for the genes encoding Vero cytotoxins 1 and 2 in hybridization experiments on faecal samples, Vero cytotoxin-producing Escherichia coli (VTEC) of serogroup O 157 were detected in 21 of 63 cases of haemorrhagic colitis, 9 of 31 cases of non-bloody diarrhoea and 14 of 68 cases of haemolytic ur...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800054261
更新日期:1988-10-01 00:00:00
abstract::Norovirus is the most frequent cause of acute infectious gastroenteritis and it is difficult to control in crowded environments like hospitals and nursing homes. Transmission depends on oral intake of virus deposited in the environment by infectious subjects. Data from volunteer studies indicate that virus concentrati...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S095026881400274X
更新日期:2015-06-01 00:00:00
abstract::Previous reports in the literature suggest that Burkholderia pseudomallei strains can be differentiated on the basis of animal virulence. Twenty environmentally and clinically derived isolates of Burkholderia pseudomallei were examined for the production of exoenzymes, morphological and biochemical phenotypes and viru...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s095026889600739x
更新日期:1997-04-01 00:00:00
abstract::There has been a worldwide increase in bed bug infestations over the last 10-15 years. A major stigma is placed upon the institutions found to be infested. We report our experience with an outbreak of the tropical bed bug, Cimex hemipterus, in a neonatal unit. The outbreak not only affected the admitted newborns and m...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268814003690
更新日期:2015-10-01 00:00:00
abstract::Tri-County Health Department investigated an outbreak of cryptosporidiosis linked to a community swimming pool. A cohort study was conducted in 37 persons who were invited to the pool party; 12 (57%) of 21 attendees had primary cryptosporidiosis infection. Risk factors for illness included swimming, getting water in m...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268809002696
更新日期:2009-11-01 00:00:00
abstract::A retrospective cohort study was conducted from 1 January 2006 to 31 December 2009 in Michigan to estimate the prevalence of HIV and hepatitis co-infection and identify associated factors. The prevalence of co-infection was 4.1% [95% confidence interval (CI) 3.8-4.5]. Multivariable logistic regression analysis reveale...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268813000538
更新日期:2013-12-01 00:00:00
abstract::During 2004 and at the start of 2005 a university hospital in Southwest Germany was affected by an extensive outbreak of vancomycin-resistant Enterococcus faecium (VRE). Although the outbreak was contained, linezolid-resistant enterococci emerged during and after the outbreak as the usage of linezolid became more comm...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268807009508
更新日期:2008-08-01 00:00:00
abstract::Ireland reports the highest incidence of verotoxigenic Escherichia coli (VTEC) infection in Europe. This study investigated potential risk factors for confirmed sporadic and outbreak primary VTEC infections during 2008-2013. Overall, 989 VTEC infections including 521 serogroup O157 and 233 serogroup O26 were geo-refer...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S095026881600193X
更新日期:2017-01-01 00:00:00
abstract::In recent years, the effect of Toxoplasma gondii infection on the cerebrum and neuropsychiatric patients has been increasingly highlighted. However, there is limited information about the epidemiology of T. gondii infection in psychiatric patients in Shandong province, eastern China. Therefore, through a case-control ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268814003835
更新日期:2015-10-01 00:00:00
abstract::Medical records, for 2000 and 2001, of symptomatic amoebic patients who were treated at our hospitals in Tokyo, Yokohama and Osaka were studied retrospectively for the purpose of gathering epidemiological data on symptomatic Entamoeba histolytica infection. A total of 58 patients were treated. Fifty-five of them were ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268803001389
更新日期:2004-01-01 00:00:00
abstract::Effective primary prevention of congenital toxoplasmosis requires up to date information on locally relevant risk factors for infection in pregnant women. In Naples, risk factors for toxoplasma infection were compared in recently infected women (as assessed by detection of specific IgM in serum) and susceptible, IgG n...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800052675
更新日期:1996-06-01 00:00:00
abstract::SUMMARYA prospective cohort study with a 1-year telephone follow-up was performed to estimate the incidence of surgical-site infections (SSIs) in hip and knee prostheses. Twenty-five public hospitals equipped with orthopaedic units in two Italian regions were involved. An 8-month surveillance period was set to obtain ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268810001627
更新日期:2011-05-01 00:00:00
abstract::To assess the burden of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in a high-risk population, the monthly incidence of laboratory-confirmed MRSA in service members/trainees stationed at Fort Benning, Georgia, USA without hospitalization or surgery documented 30 days prior to infection w...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268810000142
更新日期:2010-05-01 00:00:00
abstract::Mycoplasma pneumoniae outbreaks cause increased use of macrolides and tetracyclines. We aimed to investigate whether drug use data, in addition to laboratory data, could improve understanding of the spread of M. pneumoniae epidemics. Number of users of Mycoplasma antibiotics (erythromycin, doxycycline, clarithromycin)...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268814002908
更新日期:2015-07-01 00:00:00
abstract::Dromedary camels have been shown to be the main reservoir for human Middle East respiratory syndrome (MERS) infections. This systematic review aims to compile and analyse all published data on MERS-coronavirus (CoV) in the global camel population to provide an overview of current knowledge on the distribution, spread ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S095026881800345X
更新日期:2019-01-01 00:00:00
abstract::Laboratory-based surveillance of invasive pneumococcal infections in adults in Finland from 1983 to 1992 identified 862 episodes of pneumococcal bacteraemia and 97 episodes of meningitis. The overall incidence of invasive pneumococcal infections was 9.1 per 100,000 for all adults per year, but 27.1, 35.8, and 44.5 per...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268896007169
更新日期:1997-02-01 00:00:00
abstract::This study measured the prevalence and the risk factors associated with HCV antibody-positive prisoners. A total of 630 prisoners completed a questionnaire about risk behaviours associated with HCV transmission and were tested for HCV antibody from a blood test. Of these 362 (57.5%) prisoners were HCV antibody positiv...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268803001882
更新日期:2004-06-01 00:00:00