The prevalence of antibodies to hepatitis A virus and its determinants in The Netherlands: a population-based survey.


:The prevalence of antibodies to hepatitis A virus was assessed in a Dutch nationwide sample (n = 7367). A questionnaire was used to study the association with various sociodemographic characteristics. Overall, 33.8% (95% CI 31.6-36%) of the population had hepatitis A antibodies. The seroprevalence was less than 10% in people under 35; it increased from 25% at 35 years to 85% at 79 years. For those 15-49 years of age, Turks (90.9%) and Moroccans (95.8%) had greater seroprevalence than autochthonous Dutch (20.2%) and other Western people (25%). Low or middle socio-economic status, as indicated by the highest educational level achieved, was associated with greater seroprevalence, independently of age and reported immunization (OR 2.11 and 1.45; 95% CI 1.67-2.67 and 1.11-1.89, respectively). These data suggest autochthonous Dutch and other Westerners born after World War II were exposed to hepatitis A during childhood less frequently than older birth cohorts. Thus, more susceptibility is likely in the coming decades. Since this means a greater risk of outbreaks in future years, and since morbidity and mortality are more frequent in older persons, studying the cost effectiveness of selective and general vaccination might be worthwhile.


Epidemiol Infect


Termorshuizen F,Dorigo-Zetsma JW,de Melker HE,van den Hof S,Conyn-Van Spaendonck MA




Has Abstract


2000-06-01 00:00:00












  • Serological diagnosis of leishmaniasis: on detecting infection as well as disease.

    abstract::Serological tests are very frequently used in epidemiological surveys of leishmaniasis and other parasitoses. Their sensitivity and specificity are generally defined with respect to parasitism and disease, rather than infection. The reason is that known positives are those individuals most likely to yield parasites, o...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Dye C,Vidor E,Dereure J

    更新日期:1993-06-01 00:00:00

  • Priorities in global measles control: report of an outbreak in N'Djamena, Chad.

    abstract::In N'Djamena, capital of Chad, measles vaccination coverage of 12-23-month-old children fell from 61% in 1990 to 15% in 1993. A community survey of measles after an outbreak in 1993 showed that among children < 5 years of age, the mean monthly attack rate was 37 per 1,000 (95% CI, 32-43) and the mean case fatality rat...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Ndikuyeze A,Cook A,Cutts FT,Bennett S

    更新日期:1995-10-01 00:00:00

  • Surveillance of severe invasive group-G streptococcal infections and molecular typing of the isolates in Japan.

    abstract::The number of patients with severe invasive group-G streptococcal (Streptococcus dysgalactiae subsp. equisimilis) infections has been increasing in Japan. The emm genotypes and SmaI-digested pulsed-field gel electrophoresis DNA profiles were variable among the strains isolated, suggesting there has not been clonal exp...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Ikebe T,Murayama S,Saitoh K,Yamai S,Suzuki R,Isobe J,Tanaka D,Katsukawa C,Tamaru A,Katayama A,Fujinaga Y,Hoashi K,Watanabe H,Working Group for Streptococci in Japan.

    更新日期:2004-01-01 00:00:00

  • High prevalence of Legionella in non-passenger merchant vessels.

    abstract::There is a paucity of information on the risk from potable water in non-passenger merchant vessels (NPMVs) particularly with regard to Legionella and other bacteria. This retrospective study examined water samples from 550 NPMVs docked in eight UK ports. A total of 1027 samples from 412 NPMVs were examined for total a...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Collins SL,Stevenson D,Mentasti M,Shaw A,Johnson A,Crossley L,Willis C

    更新日期:2017-03-01 00:00:00

  • Shelter crowding and increased incidence of acute respiratory infection in evacuees following the Great Eastern Japan Earthquake and tsunami.

    abstract::Although outbreaks of acute respiratory infection (ARI) at shelters are hypothesized to be associated with shelter crowding, no studies have examined this relationship. We conducted a retrospective study by reviewing medical records of evacuees presenting to one of the 37 clinics at the shelters in Ishinomaki city, Ja...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Kawano T,Tsugawa Y,Nishiyama K,Morita H,Yamamura O,Hasegawa K

    更新日期:2016-03-01 00:00:00

  • Salmonella Typhimurium in livestock in Great Britain - trends observed over a 32-year period.

    abstract::In this retrospective study, we describe and analyse Salmonella data from four livestock species in Great Britain between 1983 and 2014, focusing on Salmonella Typhimurium. A total of 96 044 Salmonella isolates were obtained during the study period. S. Typhimurium was the predominant serovar isolated from cattle and p...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Mueller-Doblies D,Speed KCR,Kidd S,Davies RH

    更新日期:2018-03-01 00:00:00

  • A community waterborne outbreak of gastro-enteritis attributed to Shigella sonnei.

    abstract::An outbreak of gastro-enteritis occurred in a community of 2213 persons located near the city of Ioannina, in North-western Greece. Two hundreds and eighty-eight inhabitants of the village of Eleoussa, suffered from gastro-enteritis between 11 and 22 October. The peak of the epidemic occurred during the first 3 days (...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Alamanos Y,Maipa V,Levidiotou S,Gessouli E

    更新日期:2000-12-01 00:00:00

  • Viruses in acute gastroenteritis in children in Pune, India.

    abstract::A 2-year study from January 1981 to December 1982 was undertaken to determine the role of viruses in the causation of diarrhoea in hospitalized children in Pune, Maharashtra State, India. The stool samples of 426 children (213 diarrhoeal and 213 non-diarrhoeal controls) were investigated by electron microscopy and ELI...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Singh PB,Sreenivasan MA,Pavri KM

    更新日期:1989-04-01 00:00:00

  • Rotavirus detection by dot blot hybridization assay using a non-radioactive synthetic oligodeoxynucleotide probe.

    abstract::A synthetic oligodeoxynucleotide of 40 nucleotides corresponding to nucleotides 33-72 of the gene coding for the viral protein VP7 of rotavirus, was used as a nucleic acid probe to develop a non-radioactive hybridization method for rotavirus detection. The probe was labelled at the 3' end with biotin-7-dATP. The sensi...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Fernández J,Sandino A,Yudelevich A,Avendaño LF,Venegas A,Hinrichsen V,Spencer E

    更新日期:1992-02-01 00:00:00

  • Grouping of Salmonella enterica serotype Montevideo strains by ribotyping and IS200 profiling.

    abstract::One-hundred and twenty-one isolates of Salmonella enterica serotype Montevideo, representing different biotypes and incidents of infection detected in the UK between 1977 and 1995, were analysed by EcoRI ribotyping, PvuII ribotyping and IS200 fingerprinting. Among the isolates examined, 7 EcoRI ribotypes, 5 PvuII ribo...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Old DC,Chisholm SA,Crichton PB,Taylor A

    更新日期:2000-06-01 00:00:00

  • Conditions affecting the timing and magnitude of Hendra virus shedding across pteropodid bat populations in Australia.

    abstract::Understanding infection dynamics in animal hosts is fundamental to managing spillover and emergence of zoonotic infections. Hendra virus is endemic in Australian pteropodid bat populations and can be lethal to horses and humans. However, we know little about the factors driving Hendra virus prevalence in resevoir bat ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Páez DJ,Giles J,McCallum H,Field H,Jordan D,Peel AJ,Plowright RK

    更新日期:2017-11-01 00:00:00

  • Epidemiology of shigellosis in Teknaf, a coastal area of Bangladesh: a 10-year survey.

    abstract::The epidemiological data on shigellosis in Teknaf, a coastal area of Bangladesh, were reviewed for a 10-year period (1975-84). Certain similarities and differences were observed in the epidemiology of the disease in Teknaf when compared with urban Dhaka and rural Matlab. Similarities included: round-the-year infection...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Hossain MA,Albert MJ,Hasan KZ

    更新日期:1990-08-01 00:00:00

  • Developing a risk management framework to improve public health outcomes by enumerating Salmonella in ground turkey.

    abstract::Salmonella spp. continue to be a leading cause of foodborne morbidity worldwide. To assess the risk of foodborne disease, current national regulatory schemes focus on prevalence estimates of Salmonella and other pathogens. The role of pathogen quantification as a risk management measure and its impact on public health...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Sampedro F,Wells SJ,Bender JB,Hedberg CW

    更新日期:2018-12-06 00:00:00

  • Seroprevalence, correlates and trends of Helicobacter pylori infection in the Israeli population.

    abstract::We examined the prevalence, correlates and trends of H. pylori infection in Israel using residual sera obtained in 2007-2008 from 1466 Jewish subjects aged 0-77 years and 897 Arabs aged 0-19 years, and in 2000-2001 from 627 Jewish and 575 Arab subjects aged 0-19 years. H. pylori IgG antibodies were measured by ELISA. ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Muhsen K,Cohen D,Spungin-Bialik A,Shohat T

    更新日期:2012-07-01 00:00:00

  • High-level vancomycin-resistant enterococci causing hospital infections.

    abstract::Nosocomial infection or colonization due to enterococci with high-level resistance to vancomycin (minimal inhibitory concentrations [MICs] between 64 and greater than 2000 mg/L) has occurred in 41 patients with renal disease. These vancomycin-resistant enterococci were cultured from many sources including blood. All b...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Uttley AH,George RC,Naidoo J,Woodford N,Johnson AP,Collins CH,Morrison D,Gilfillan AJ,Fitch LE,Heptonstall J

    更新日期:1989-08-01 00:00:00

  • Cryptosporidiosis from a community swimming pool: outbreak investigation and follow-up study.

    abstract::Tri-County Health Department investigated an outbreak of cryptosporidiosis linked to a community swimming pool. A cohort study was conducted in 37 persons who were invited to the pool party; 12 (57%) of 21 attendees had primary cryptosporidiosis infection. Risk factors for illness included swimming, getting water in m...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Boehmer TK,Alden NB,Ghosh TS,Vogt RL

    更新日期:2009-11-01 00:00:00

  • Escherichia coli O157:H7 infection of calves: infectious dose and direct contact transmission.

    abstract::Cattle are considered to be a reservoir host of Escherichia coli O157:H7 and contaminated foods of bovine origin are important vehicles of human infection. In this study, the susceptibility of calves to experimental E. coli O157:H7 infection following low oral exposures was determined. Two of 17 calves exposed to very...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Besser TE,Richards BL,Rice DH,Hancock DD

    更新日期:2001-12-01 00:00:00

  • A school outbreak of pandemic (H1N1) 2009 infection: assessment of secondary household transmission and the protective role of oseltamivir.

    abstract::In mid-June 2009, an outbreak of pandemic (H1N1) 2009 (pH1N1) infection occurred in a secondary school in Hong Kong. We carried out an epidemiological investigation to delineate the characteristics of the outbreak, gauge the extent of secondary household transmission, and assess the protective role of oseltamivir in h...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Leung YH,Li MP,Chuang SK

    更新日期:2011-01-01 00:00:00

  • Age-specific mixing generates transient outbreak risk following critical-level vaccination.

    abstract::Measles elimination goals have been adopted in a range of countries, sub-regions, and regions since the WHO declared an elimination goal by 2015 or 2020. All countries attempt to achieve and maintain high coverage through routine immunization programmes. This routine strategy, however, does not ensure the elimination ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Bhattacharyya S,Ferrari MJ

    更新日期:2017-01-01 00:00:00

  • The epidemiology of, and risk factors for, mortality from severe sepsis and septic shock in a tertiary-care university hospital setting.

    abstract::This study investigated the clinical characteristics of, and outcomes and risk factors for hospital mortality of 390 patients admitted with severe sepsis or septic shock in an intensive care unit (ICU). Prospectively collected data from patients collected between 1 July 2004 and 30 June 2006 were analysed. Overall hos...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Khwannimit B,Bhurayanontachai R

    更新日期:2009-09-01 00:00:00

  • British Escherichia coli O157 in Cattle Study (BECS): to determine the prevalence of E. coli O157 in herds with cattle destined for the food chain.

    abstract::Escherichia coli O157 are zoonotic bacteria for which cattle are an important reservoir. Prevalence estimates for E. coli O157 in British cattle for human consumption are over 10 years old. A new baseline is needed to inform current human health risk. The British E. coli O157 in Cattle Study (BECS) ran between Septemb...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Henry MK,Tongue SC,Evans J,Webster C,McKENDRICK IJ,Morgan M,Willett A,Reeves A,Humphry RW,Gally DL,Gunn GJ,Chase-Topping ME

    更新日期:2017-11-01 00:00:00

  • Multistate foodborne disease outbreaks associated with raw tomatoes, United States, 1990-2010: a recurring public health problem.

    abstract::We examined multistate outbreaks attributed to raw tomatoes in the United States from 1990 to 2010. We summarized the demographic and epidemiological characteristics of 15 outbreaks resulting in 1959 illnesses, 384 hospitalizations, and three deaths. Most (80%) outbreaks were reported during 2000-2010; 73% occurred Ma...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Bennett SD,Littrell KW,Hill TA,Mahovic M,Behravesh CB

    更新日期:2015-05-01 00:00:00

  • Detection of antibodies to Japanese encephalitis virus in the wild boars in Hiroshima prefecture, Japan.

    abstract::Serum specimens were collected from 25 wild boars in Hiroshima prefecture located in the western region of Japan from November 2004 to February 2005. The sera were tested for antibodies to Japanese encephalitis virus (JEV) by IgM capture and IgG enzyme-linked immunosorbent assays (ELISA), and plaque reduction neutrali...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Hamano M,Lim CK,Takagi H,Sawabe K,Kuwayama M,Kishi N,Kurane I,Takasaki T

    更新日期:2007-08-01 00:00:00

  • Trimethoprim resistance in commensal bacteria isolated from farm animals.

    abstract::Trimethoprim resistance was examined in faecal bacteria obtained from chickens, sheep, cattle and pigs. The incidence of trimethoprim resistance in porcine strains was 17% (157/922) and, whereas 15.8% (146/922) of these bacteria were highly resistant, only 4% (37/922) of the isolates possessed trimethoprim resistance ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Amyes SG

    更新日期:1987-02-01 00:00:00

  • The fall and rise of Group A Streptococcus diseases.

    abstract::Streptococcus pyogenes (or Group A Streptococcus, GAS) is a Gram-positive human pathogen responsible for a diverse array of superficial, invasive and immune-related diseases. GAS infections have historically been diseases of poverty and overcrowding, and remain a significant problem in the developing world and in disa...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Barnett TC,Bowen AC,Carapetis JR

    更新日期:2018-08-15 00:00:00

  • A dot-blot hybridization procedure for the detection of astrovirus in stool samples.

    abstract::We have developed a nucleic acid dot-blot hybridization test for the detection of astroviruses in stool samples. The test was not as sensitive as electron microscopy for the detection of low numbers of well preserved astrovirus particles, but was able to identify astroviruses in stools containing particles of indistin...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Willcocks MM,Carter MJ,Silcock JG,Madeley CR

    更新日期:1991-10-01 00:00:00

  • Epidemiological analysis of Trichinella spiralis infections of foxes in Brandenburg, Germany.

    abstract::In a cross-sectional study conducted between March 1993 and February 1995, 7103 indiscriminately collected foxes were examined for Trichinella larvae. A total of 3295 serum samples were serologically investigated with an ELISA based on excretory-secretory antigen. The proportion of serologically positive animals range...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,多中心研究


    authors: Wacker K,Rodriguez E,Garate T,Geue L,Tackmann K,Selhorst T,Staubach C,Conraths FJ

    更新日期:1999-08-01 00:00:00

  • Comparison of routine field epidemiology and whole genome sequencing to identify tuberculosis transmission in a remote setting.

    abstract::Yukon Territory (YT) is a remote region in northern Canada with ongoing spread of tuberculosis (TB). To explore the utility of whole genome sequencing (WGS) for TB surveillance and monitoring in a setting with detailed contact tracing and interview data, we used a mixed-methods approach. Our analysis included all cult...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Guthrie JL,Strudwick L,Roberts B,Allen M,McFadzen J,Roth D,Jorgensen D,Rodrigues M,Tang P,Hanley B,Johnston J,Cook VJ,Gardy JL

    更新日期:2020-02-04 00:00:00

  • Outbreaks of infection with methicillin-resistant Staphylococcus aureus on neonatal and burns units of a new hospital.

    abstract::Multiple introductions of methicillin-resistant Staphylococcus aureus (MRSA) strains occurred to a new hospital in Hong Kong. Two years of clinical microbiological surveillance of the resulting outbreaks was combined with laboratory investigation by phage and antibiogram typing, and plasmid profiling. The outbreaks on...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Farrington M,Ling J,Ling T,French GL

    更新日期:1990-10-01 00:00:00

  • Cowpox: reservoir hosts and geographic range.

    abstract::It is generally accepted that the reservoir hosts of cowpox virus are wild rodents, although direct evidence for this is lacking for much of the virus's geographic range. Here, through a combination of serology and PCR, we demonstrate conclusively that the main hosts in Great Britain are bank voles, wood mice and shor...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Chantrey J,Meyer H,Baxby D,Begon M,Bown KJ,Hazel SM,Jones T,Montgomery WI,Bennett M

    更新日期:1999-06-01 00:00:00