Antigenic and genetic analyses of eight influenza C strains isolated in various areas of Japan during 1985-9.

Abstract:

:Eight strains of influenza C virus isolated in various areas of Japan between January 1985 and January 1989 were compared using monoclonal antibodies to the haemagglutinin-esterase (HE) glycoproteins and by oligonucleotide mapping of total vRNA. Five of six strains isolated during 1986-9 were closely related to one another and also resembled the virus, C/Aichi/1/81, isolated in 1981 in Aichi prefecture. This suggests that the C/Aichi/1/81-related viruses had an epidemiological advantage over any co-circulating viruses at least during that period. One of two 1985 isolates (C/Nara/1/85) was antigenically indistinguishable from the C/Mississippi/1/80 strain though their oligonucleotide patterns were markedly different from each other. This raises the possibility that C/Nara/1/85 may be a recombinant virus which receives its HE gene from the C/Mississippi/1/80-related parent.

journal_name

Epidemiol Infect

authors

Ohyama S,Adachi K,Sugawara K,Hongo S,Nishimura H,Kitame F,Nakamura K

doi

10.1017/s0950268800049827

subject

Has Abstract

pub_date

1992-04-01 00:00:00

pages

353-65

issue

2

eissn

0950-2688

issn

1469-4409

journal_volume

108

pub_type

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