Abstract:
:The shift in ocular dominance induced by brief monocular deprivation is greatest during a postnatal critical period and is thought to decline irreversibly thereafter. However, here we demonstrate that complete visual deprivation through dark exposure restores rapid ocular dominance plasticity in adult rats. In addition, the loss of visual acuity resulting from chronic monocular deprivation is reversed if dark exposure precedes removal of the occlusion in adulthood, suggesting a potential use for dark exposure in the treatment of adult amblyopia.
journal_name
Nat Neuroscijournal_title
Nature neuroscienceauthors
He HY,Ray B,Dennis K,Quinlan EMdoi
10.1038/nn1965subject
Has Abstractpub_date
2007-09-01 00:00:00pages
1134-6issue
9eissn
1097-6256issn
1546-1726pii
nn1965journal_volume
10pub_type
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