Abstract:
:During development, newly born neurons migrate away from their initial birth sites to their final positions in the mature brain. The neurotrophin BDNF has been shown to regulate the migration of granule cells in the cerebellum. The cellular mechanisms that mediate this chemotactic response have not been resolved. In this issue of Neuron, Zhou et al. show that vesicle trafficking is critical for allowing neurons to respond to a gradient of BDNF.
journal_name
Neuronjournal_title
Neuronauthors
Kaplan DR,Miller FDdoi
10.1016/j.neuron.2007.06.025subject
Has Abstractpub_date
2007-07-05 00:00:00pages
1-2issue
1eissn
0896-6273issn
1097-4199pii
S0896-6273(07)00459-Xjournal_volume
55pub_type
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