Abstract：
:Sexually dimorphic behaviors are likely to involve neural pathways that express the androgen receptor (AR). We have genetically modified the AR locus to visualize dimorphisms in neuronal populations that express AR. Analysis of AR-positive neurons reveals both known dimorphisms in the preoptic area of the hypothalamus and the bed nucleus of the stria terminalis as well as novel dimorphic islands in the basal forebrain with a clarity unencumbered by the vast population of AR-negative neurons. This genetic approach allows the visualization of dimorphic subpopulations of AR-positive neurons along with their projections and may ultimately permit an association between neural circuits and specific dimorphic behaviors.
journal_name
Neuronjournal_title
Neuronauthors
Shah NM,Pisapia DJ,Maniatis S,Mendelsohn MM,Nemes A,Axel Rdoi
10.1016/j.neuron.2004.07.008subject
Has Abstractpub_date
2004-08-05 00:00:00pages
313-9issue
3eissn
0896-6273issn
1097-4199pii
S0896627304004258journal_volume
43pub_type
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