Abstract:
:Nitric oxide (NO) is a putative neuronal messenger in the olfactory epithelium. We analysed the electrical responses of rat olfactory receptor neurones to NO stimulation in the whole-cell patch clamp mode and found that NO activates the cyclic nucleotide-gated conductance, independent from cyclic GMP. As NO may also open calcium-dependent potassium channels and raise cyclic GMP levels, it appears to act as a complex modulator of olfactory receptor neuron physiology in vivo.
journal_name
Brain Resjournal_title
Brain researchauthors
Schmachtenberg O,Diaz J,Bacigalupo Jdoi
10.1016/s0006-8993(03)02990-1subject
Has Abstractpub_date
2003-08-01 00:00:00pages
146-50issue
1eissn
0006-8993issn
1872-6240pii
S0006899303029901journal_volume
980pub_type
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