Human neural stem cells express extra-neural markers.

Abstract:

:Neural stem cells can be derived from the adult/embryonic nervous system as well as from more primitive embryonic stem cells but, because of the lack of specific markers, only their differentiated progeny can be characterized. We here report the presence of several endothelial and hematopoietic receptors (at protein and mRNA level) on the surface of embryonic human neural stem cells, which are partially maintained during differentiation. This suggests that neural stem cells have a greater potential than previously thought, which involves the ability to respond to different and so far unconsidered environmental signals and may be responsible for the recently discovered process of stem cell-fate conversion.

journal_name

Brain Res

journal_title

Brain research

authors

Parati EA,Bez A,Ponti D,de Grazia U,Corsini E,Cova L,Sala S,Colombo A,Alessandri G,Pagano SF

doi

10.1016/s0006-8993(01)03291-7

subject

Has Abstract

pub_date

2002-01-25 00:00:00

pages

213-21

issue

2

eissn

0006-8993

issn

1872-6240

pii

S0006899301032917

journal_volume

925

pub_type

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