Abstract:
:Neural stem cells can be derived from the adult/embryonic nervous system as well as from more primitive embryonic stem cells but, because of the lack of specific markers, only their differentiated progeny can be characterized. We here report the presence of several endothelial and hematopoietic receptors (at protein and mRNA level) on the surface of embryonic human neural stem cells, which are partially maintained during differentiation. This suggests that neural stem cells have a greater potential than previously thought, which involves the ability to respond to different and so far unconsidered environmental signals and may be responsible for the recently discovered process of stem cell-fate conversion.
journal_name
Brain Resjournal_title
Brain researchauthors
Parati EA,Bez A,Ponti D,de Grazia U,Corsini E,Cova L,Sala S,Colombo A,Alessandri G,Pagano SFdoi
10.1016/s0006-8993(01)03291-7subject
Has Abstractpub_date
2002-01-25 00:00:00pages
213-21issue
2eissn
0006-8993issn
1872-6240pii
S0006899301032917journal_volume
925pub_type
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