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The search for the ideal biocatalyst.

Abstract：

:While the use of enzymes as biocatalysts to assist in the industrial manufacture of fine chemicals and pharmaceuticals has enormous potential, application is frequently limited by evolution-led catalyst traits. The advent of designer biocatalysts, produced by informed selection and mutation through recombinant DNA technology, enables production of process-compatible enzymes. However, to fully realize the potential of designer enzymes in industrial applications, it will be necessary to tailor catalyst properties so that they are optimal not only for a given reaction but also in the context of the industrial process in which the enzyme is applied.

journal_name

Nat Biotechnol

journal_title

Nature biotechnology

authors

Burton SG,Cowan DA,Woodley JM

doi

10.1038/nbt0102-37

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

37-45

issue

1

eissn

1087-0156

issn

1546-1696

pii

nbt0102-37

journal_volume

20

pub_type

杂志文章,评审

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