GFR alpha-1 is expressed in parvalbumin GABAergic neurons in the hippocampus.

abstract：:The present study has examined the involvement of sensory neurotransmitters in activating neurones in the trigeminal nucleus caudalis following stimulation of the trigeminovascular system in anaesthetised guinea-pigs. Electrical stimulation of the right trigeminal ganglion produced a unilateral expression of Fos-like ...

journal_title：Brain research

authors： Clayton JS,Gaskin PJ,Beattie DT

更新日期：1997-11-14 00:00:00

abstract：:Preparations of lysed synaptosomes exhibit a high affinity Ca2+/Mg2+ ATPase and ATP-dependent Ca2+ accumulation activity, with a Km for Ca2+ congruent to 0.5 microM, close to the cytosolic concentration of Ca2+. When these membrane suspensions were incubated with cholinergic agonists muscarine or oxotremorine (1-20 mi...

journal_title：Brain research

authors： Ross DH,Shreeve SM,Hamilton MG

更新日期：1985-03-11 00:00:00

abstract：:The understanding of sentences involves not only the retrieval of the meaning of single words, but the identification of the relation between a verb and its arguments. The way the brain manages to process word meaning and syntactic relations during language comprehension on-line still is a matter of debate. Here we re...

journal_title：Brain research

authors： Friederici AD,Weissenborn J

更新日期：2007-05-18 00:00:00

abstract：:Prolonged electrical stimulation of the perforant pathway in the rat evokes epileptiform discharges in dentate granule cells and irreversibly damages hilar neurons. In this in vivo study, we demonstrate that similar perforant path stimulation in C57Bl/6 mice causes the same pattern of hippocampal neuron loss. Therefor...

journal_title：Brain research

authors： Kienzler F,Jedlicka P,Vuksic M,Deller T,Schwarzacher SW

更新日期：2006-04-26 00:00:00

abstract：:Determining the mechanism by which fluorescent retrograde neuronal tracers are taken up requires knowledge of their composition. It has been claimed that Fluoro-Gold, a retrogradely transported fluorescent neuronal tracer, is 2-hydroxy-4,4'-diamidinostilbene (hydroxystilbamidine), an amidine antibiotic. However, this ...

journal_title：Brain research

authors： Wessendorf MW

更新日期：1991-07-05 00:00:00

abstract：:Methamphetamine (METH) is one of the most commonly abused psychostimulant, and is known to induce dopaminergic neurotoxicity by generating oxidative stress and free radicals. In the present study we investigated the effects of METH on egr-1 and c-fos immediate early gene induction in different regions of mouse brain, ...

journal_title：Brain research

authors： Thiriet N,Zwiller J,Ali SF

更新日期：2001-11-16 00:00:00

abstract：:Protein uptake and transport within the brain stem vasculature of mechanically brain injured cats was studied by means of both light and electron microscopy utilizing intravenously injected horseradish peroxidase as the protein tracer. In animals sustaining low grade head injuries not of sufficient intensity to elicit...

journal_title：Brain research

authors： Povlishock JT,Becker DP,Sullivan HG,Miller JD

更新日期：1978-09-22 00:00:00

abstract：:The ultrastructural localizations of rat corticoliberin (rCRF) and methionine-enkephalin octapeptide (Met-Enk-8) in the external layer of the rat median eminence were examined by double-immunogold labeling with anti-rCRF and anti-Met-Enk-8 sera labeled with small-sized (Gs) and medium-sized (Gm) gold particles, respec...

journal_title：Brain research

authors： Hisano S,Daikoku S,Yanaihara N,Shibasaki T

更新日期：1986-04-09 00:00:00

abstract：:We used double-barreled pH-sensitive microelectrodes to study the mechanisms by which the intracellular pH is regulated in the connective glial cells of the medicinal leech. The experiments indicate that a Cl(-)- and HCO3(-)-dependent mechanism mediates some recovery from intracellular alkalosis even in the absence of...

journal_title：Brain research

authors： Szatkowski MS,Schlue WR

更新日期：1994-11-28 00:00:00

abstract：:ASIC3-immunoreactivity (ir) was examined in the rat vagal and glossopharyngeal sensory ganglia. In the jugular, petrosal and nodose ganglia, 24.8%, 30.8% and 20.6% of sensory neurons, respectively, were immunoreactive for ASIC3. These neurons were observed throughout the ganglia. A double immunofluorescence method dem...

journal_title：Brain research

authors： Fukuda T,Ichikawa H,Terayama R,Yamaai T,Kuboki T,Sugimoto T

更新日期：2006-04-07 00:00:00

abstract：:The aim of this study was to evaluate spatial organization of hyperactive microglial cells in trigeminal spinal subnucleus caudalis (Vc) and upper cervical spinal cord (C1), and to clarify the involvement in mechanisms underlying orofacial secondary hyperalgesia following infraorbital nerve injury. We found that the h...

journal_title：Brain research

authors： Shibuta K,Suzuki I,Shinoda M,Tsuboi Y,Honda K,Shimizu N,Sessle BJ,Iwata K

更新日期：2012-04-27 00:00:00

abstract：:Neural stem cells (NSCs) give rise to the central nervous system (CNS) and persist in certain areas of adult brains for replenishing damaged differentiated cells. The loss of the balance between NSC self-renewal and differentiation could lead to tumor formation such as the occurrence of glioblastoma (GBM), the most co...

journal_title：Brain research

authors： Shen F,Song C,Liu Y,Zhang J,Wei Song S

更新日期：2019-02-01 00:00:00

abstract：:Intracisternal (i.c.) administration of the endogenous tridecapeptide neurotensin (NT) has been previously shown to significantly reduce the incidence of cold-restraint stress (CRS)-induced gastric ulcers in rats. In this study we confirm the cytoprotective activity of central NT, and document structure-activity relat...

journal_title：Brain research

authors： Hernandez DE,Richardson CM,Nemeroff CB,Orlando RC,St-Pierre S,Rioux F,Prange AJ Jr

更新日期：1984-05-28 00:00:00

abstract：:Increases in extracellular potassium concentrations reliably increase burst rates in cultured fetal murine spinal cord networks. This effect could be mimicked by either blocking voltage-gated potassium conductances or facilitating excitatory synaptic interactions, but not by blocking specific calcium-dependent potassi...

journal_title：Brain research

authors： Rhoades BK,Gross GW

更新日期：1994-04-18 00:00:00

abstract：:Specific silver impregnation techniques for extracellular amyloid and intraneuronal neurofibrillary changes were used to examine the presubiculum in Alzheimer victims. Extended amyloid clouds in the absence of neurofibrillary changes were noted in the parvopyramidal layer of the presubiculum proper. The corresponding ...

journal_title：Brain research

authors： Kalus P,Braak H,Braak E,Bohl J

更新日期：1989-08-07 00:00:00

abstract：:Vanadate (VO-3), an essential trace element with insulin-mimetic actions, produces systemic hyperglycemia following central administration in mice. The hyperglycemic effect is due to specific action of vanadate or its reduced form, vanadyl (VO2+); other ions of similar atomic weight (Cr, Mn) or structure (phosphate) h...

journal_title：Brain research

authors： Amir S,Meyerovitch J,Shechter Y

更新日期：1987-09-01 00:00:00

abstract：:To examine the role played by the basal forebrain cholinergic system in cortical activation, neuronal activity was investigated in the globus pallidus and substantia innominata of urethane-anaesthetized rats during large cortical slow waves and spontaneous or elicited low voltage fast activity. An effort was made to i...

journal_title：Brain research

authors： Détári L,Vanderwolf CH

更新日期：1987-12-22 00:00:00

abstract：:Two pathways that have been shown to mediate cerebral ischemic damage are the MEK/ERK cascade and the pro-apoptotic deltaPKC pathway. We investigated the relationship between these pathways in a rat model of focal ischemia by observing and modifying the activation state of each pathway. The ERK1/2 inhibitor, U0126, in...

journal_title：Brain research

authors： Castañeda D,Zhao H,Mochly-Rosen D,Steinberg GK

更新日期：2009-01-28 00:00:00

abstract：:Glioblastoma is the most common primary brain tumor in adults from which about 15,000 patients die each year in the United States. Despite aggressive surgery, radiotherapy and chemotherapy, median survival remains only 1 year. Here we evaluate growth of primary human brain tumor cells in a defined nutrient culture med...

journal_title：Brain research

authors： Brewer GJ,LeRoux PD

更新日期：2007-07-09 00:00:00

abstract：:Gastrin-releasing peptide (GRP) mediated signals in the central nervous system (CNS) influence many functions associated with energy metabolism. The purpose of the present study was to investigate the central effect of GRP on glucose metabolism in the male rat. Intracerebroventricular (icv) administration of GRP cause...

journal_title：Brain research

authors： Jha PK,Foppen E,Challet E,Kalsbeek A

更新日期：2015-11-02 00:00:00

abstract：:To determine the mechanisms underlying the depolarization induced by anoxia in brainstem neurons, we studied single neurons in brainstem slices using conventional micro-electrodes and freshly dissociated hypoglossal and vagal cells using patch clamp techniques (whole-cell configuration). Since glutamate concentration ...

journal_title：Brain research

authors： Haddad GG,Jiang C

更新日期：1993-10-22 00:00:00

abstract：:Saccadic adaptation maintains saccade accuracy and has been studied with targeting saccades, i.e. saccades that bring the gaze to a target, with the classical intra-saccadic step procedure in which the target systematically jumps to a new position during saccade execution. Post-saccadic visual feedback about the error...

journal_title：Brain research

authors： Lavergne L,Vergilino-Perez D,Lemoine C,Collins T,Doré-Mazars K

更新日期：2011-09-30 00:00:00

abstract：:Rat pinealocytes use L-glutamate as a modulator for melatonin synthesis. Upon binding of L-glutamate to the class II metabotropic glutamate receptor, norepinephrine (NE)-dependent formation of cAMP was inhibited, resulting in decreased serotonin-N-acetyltransferase (NAT) activity and melatonin output. Although L-gluta...

journal_title：Brain research

authors： Ishio S,Yamada H,Craft CM,Moriyama Y

更新日期：1999-12-11 00:00:00

abstract：:Tissue culture preparations of the myenteric plexus from the guinea pig taenia coli have been studied by electron microscopy. Three main cell types can be identified: neurons, enteric glial cells and fibroblasts. The ultrastructure of these cells resembles that of the same cells in situ. Neuronal processes form close ...

journal_title：Brain research

authors： Bałuk P,Jessen KR,Saffrey MJ,Burnstock G

更新日期：1983-02-28 00:00:00

abstract：:Fast B neurons in bullfrog sympathetic ganglia were voltage clamped with two microelectrodes. Acetylcholine (ACh) was applied onto the soma membrane by iontophoresis. A rapid nicotinic inward current was followed by a slow muscarinic inward current. After an addition of scopolamine to Ringer solution so as to block th...

journal_title：Brain research

authors： Tokimasa T,North RA

更新日期：1984-03-19 00:00:00

abstract：:The mechanism(s) underlying age-associated diminutions in the rat striatal D2 dopamine receptor (D2-receptor) number was investigated. The levels of D2-receptor mRNA in 4-, 12- and 18-month-old rat striata were found not to change. In contrast, the levels of 110 kDa protein, labeled with a D2-receptor specific antibod...

journal_title：Brain research

authors： Sakata M,Farooqui SM,Prasad C

更新日期：1992-03-20 00:00:00

abstract：:Ethanol administration in long-sleep (LS) and short-sleep (SS) mice results in a large number of Fos-IR neurons in the supraoptic nucleus (SON) in LS, and almost no Fos-IR neurons in the same nucleus in SS mice. In contrast, isotonic saline, hypertonic saline, with or without ethanol, resulted in a similar pattern of ...

journal_title：Brain research

authors： Eisenman LM,Donovan HS,Johnson TE

更新日期：2002-05-10 00:00:00

abstract：:The peptide NK1-receptor antagonists, sendide and [D-Trp7]sendide, have been evaluated for antinociceptive activity in the capsaicin test. Both peptides, injected intrathecally (i.t.) 5 min prior to intraplantar capsaicin, produced a dose-dependent reduction of the capsaicin-induced paw licking response. Naloxone (4.0...

journal_title：Brain research

authors： Sakurada T,Yogo H,Katsumata K,Tan-No K,Sakurada S,Kisara K,Ohba M

更新日期：1994-06-27 00:00:00

abstract：:We report here the results of an autoradiographic analysis of the postnatal development of the hippocampal glucocorticoid receptor system in the rat brain. Quantitative analysis of the autoradiograms revealed a varied pattern of gradual development towards adult receptor concentrations during the second week of life. ...

journal_title：Brain research

authors： Meaney MJ,Sapolsky RM,McEwen BS

更新日期：1985-02-01 00:00:00

abstract：:Increasing evidence have shown that beta-amyloid (Abeta) induced hyperphosphorylation of tau, which eventually resulted in the disruption of microtubule (MT) integrity. Cyclin-dependent kinase 5 (CDK5) and its activator p35 are required for neurite outgrowth. The cleavage of p35 to p25, mediated by calpain and calcium...

journal_title：Brain research

authors： Chen X,Huang T,Zhang J,Song J,Chen L,Zhu Y

更新日期：2008-03-20 00:00:00