Intragranular colocalization of CRF and Met-Enk-8 in nerve terminals in the rat median eminence.

abstract：:The distinction between neural mechanisms of explicit and implicit expressions of memory has been well studied at the retrieval stage, but less at encoding. In addition, dissociations obtained in many studies are complicated by methodological difficulties in obtaining process-pure measures of different types of memory...

journal_title：Brain research

authors： Meng Y,Ye X,Gonsalves BD

更新日期：2014-10-17 00:00:00

abstract：:Ginseng, the root of Panax ginseng C.A. Meyer (Araliaceae), is a well known and popular herbal medicine used worldwide. Among more than 30 ginsenosides, the active ingredients of ginseng, ginsenosides Rb1 and Rg1 are regarded as the main compounds responsible for many pharmaceutical actions of ginseng. In our study, p...

journal_title：Brain research

authors： Radad K,Gille G,Moldzio R,Saito H,Rausch WD

更新日期：2004-09-17 00:00:00

abstract：:Tissue accumulation of ornithine (Orn), homocitrulline (Hcit), ammonia and orotic acid (Oro) is the biochemical hallmark of patients affected by hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome, a disorder clinically characterized by neurological symptoms, whose pathophysiology is practically unknown....

journal_title：Brain research

authors： Viegas CM,Zanatta A,Knebel LA,Schuck PF,Tonin AM,Ferreira Gda C,Amaral AU,Dutra Filho CS,Wannmacher CM,Wajner M

更新日期：2009-09-29 00:00:00

abstract：:Chick pineal cells contain a circadian oscillator that derives rhythmic synthesis and secretion of melatonin even in dispersed cell culture. Here, we demonstrate that the mRNA encoding tryptophan hydroxylase (TPH), the first enzyme in the melatonin synthetic pathway, is expressed rhythmically under the control of the ...

journal_title：Brain research

authors： Green CB,Besharse JC,Zatz M

更新日期：1996-10-28 00:00:00

abstract：:Chronic hydrocephalus is one of the severe complications after subarachnoid hemorrhage (SAH). However, there is no efficient treatment for the prevention of chronic hydrocephalus, partially due to poor understanding of underlying pathogenesis, subarachnoid fibrosis. Transforming growth factor-β1(TGF-β1) is a potent fi...

journal_title：Brain research

authors： Yan H,Chen Y,Li L,Jiang J,Wu G,Zuo Y,Zhang JH,Feng H,Yan X,Liu F

更新日期：2016-01-01 00:00:00

abstract：:Semaphorins constitute a family of signaling molecules with functions in axon pathfinding and neuronal migration. Neuropilins 1 and 2 have been identified as the ligand-binding component of semaphorin receptors. Both ligands and receptors are expressed in embryonic and adult organs in complementary and sometimes redun...

journal_title：Brain research

authors： Meléndez-Herrera E,Varela-Echavarría A

更新日期：2006-01-05 00:00:00

abstract：:Cerebellar explants derived from neonatal mice were exposed to cytosine arabinoside, an inhibitor of DNA synthesis. Following such exposure, the cortical regions of the explants contained numerous closely packed large neurons with few intervening elements and without lamination. The surviving large cortical neurons in...

journal_title：Brain research

authors： Seil FJ,Leiman AL,Woodward WR

更新日期：1980-03-31 00:00:00

abstract：:Previous studies have reported that schizophrenia (SZ) patients showed selective reinforcement learning deficits and abnormal feedback-related event-related potential (ERP) components. However, how the brain networks and their topological properties evolve over time during transient feedback-related cognition processi...

journal_title：Brain research

authors： Zhao Z,Wang C,Yuan Q,Zhao J,Ren Q,Xu Y,Li J,Yu Y

更新日期：2020-11-01 00:00:00

abstract：:The origin of neuronal perikarya which project to the external zone of the median eminence (the tuberoinfundibular neuronal system) was determined in the rat after injection or diffusion of wheat germ agglutinin (WGA) into the median eminence. The retrogradely transported lectin was detected in neurons using an immuno...

journal_title：Brain research

authors： Lechan RM,Nestler JL,Jacobson S

更新日期：1982-08-05 00:00:00

abstract：:To determine whether post-traumatic seizure severity would be affected by the interval between seizures and head injury, we measured seizures after various times with or without fluid percussion brain injury (2atm fluid percussion injury; FPI). To determine efficacy of anti-seizure medication, we also determined if le...

journal_title：Brain research

authors： Chen YH,Huang EY,Kuo TT,Hoffer BJ,Wu PJ,Ma HI,Tsai JJ,Chou YC,Chiang YH

更新日期：2016-07-01 00:00:00

abstract：:Simulated networks of excitatory and inhibitory neurons have previously been shown to reproduce critical features of experimental data regarding neural coding in V1, such as a positive relationship between thalamic input spike rate and the power of gamma frequency oscillations. This effect, referred to as modulated ga...

journal_title：Brain research

authors： McDonnell MD,Mohan A,Stricker C,Ward LM

更新日期：2012-01-24 00:00:00

abstract：:In a single 10-s training trial, hatchling chicks were conditioned to suppress their spontaneous peck response to a small spherical target by coating it with an aversive liquid. A 24-h test trial employing a dry target demonstrated a robust memory for the training manifested in passive avoidance behavior. Leupeptin, a...

journal_title：Brain research

authors： Davis JL,Pico RM

更新日期：1987-03-17 00:00:00

abstract：:We have previously shown that hypothyroidism produces a decrease in the number of spines counted along the apical shafts of pyramidal neurons of the cortex. Nevertheless, other authors have found that when an animal is subjected to some adverse living conditions the size of the spines decreases, making them invisible ...

journal_title：Brain research

authors： Berbel PJ,Escobar del Rey F,Morreale de Escobar G,Ruiz-Marcos A

更新日期：1985-07-01 00:00:00

abstract：:Several investigations have shown that the N-methyl-D-aspartate (NMDA) antagonist MK-801 interferes both with learning and a candidate neural mechanism for learning, the long-term potentiation (LTP) phenomenon. The low doses of MK-801 reported to block learning, however, may not be sufficient to block LTP. The present...

journal_title：Brain research

authors： Robinson GB,Reed GD

更新日期：1992-01-08 00:00:00

abstract：:The present study attempts to elucidate the possible role of adenosine 3',5'-monophosphate (cAMP) and prostaglandin E2 (PGE2) in the function of the neural luteinizing hormone-releasing hormone (LH-RH) apparatus. To this end, in vitro LH-RH release from superfused hypothalamic fragments and cAMP production by hypothal...

journal_title：Brain research

authors： Kim K,Ramirez VD

更新日期：1986-10-29 00:00:00

abstract：:This study examined the effect of feeding either a bland cornstarch-based diet (BCD) or a highly palatable, high fat diet containing sucrose (HPD) on hypothalamic arcuate nucleus (ARC) gene expression for neuropeptide-Y (NPY). Male Sprague-Dawley rats received either BCD ad libitum, HPD ad libitum, HPD pair-fed to the...

journal_title：Brain research

authors： Kim EM,Welch CC,Grace MK,Billington CJ,Levine AS

更新日期：1998-09-21 00:00:00

abstract：:Applications of acetylcholine to hippocampal slices maintained in vitro resulted in slow depolarizations and simultaneous increases in membrane resistance (RN)in hippocampal pyramidal neurons. Increases in RN had both voltage dependent and voltage independent components. These effects were associated with increases in...

journal_title：Brain research

authors： Benardo LS,Prince DA

更新日期：1981-04-27 00:00:00

abstract：:It has been demonstrated that repeated, subcutaneous administration of 3,4-methylenedioxymethamphetamine (MDMA) to rats, guinea pigs, and squirrel monkeys produces long-lasting depletions of serotonin (5-hydroxytryptamine; 5-HT) in several brain regions. Since evidence of degenerating 5-HT neurons has been observed in...

journal_title：Brain research

authors： Kleven MS,Woolverton WL,Seiden LS

更新日期：1989-05-29 00:00:00

abstract：:In recent years microvillar cells (MVC) have been identified in the olfactory epithelium of numerous species, including rodents, canines, and primates. However, there is no consensus on the morphologic or histochemical features of this cell, nor is the function of these cells currently known. Previous studies have exa...

journal_title：Brain research

authors： Miller ML,Andringa A,Evans JE,Hastings L

更新日期：1995-01-09 00:00:00

abstract：:Niemann-Pick Type C (NPC) disease is an autosomal recessive neurodegenerative disorder with abnormal lipid storage as the major cellular pathologic hallmark. Genetic analyses have identified mutations in NPC1 gene in the great majority of cases, while mutations in NPC2 account for the remainders. Yet little is known r...

journal_title：Brain research

authors： Liao G,Wen Z,Irizarry K,Huang Y,Mitsouras K,Darmani M,Leon T,Shi L,Bi X

更新日期：2010-04-14 00:00:00

abstract：:Excitatory amino acid neurotoxicity and the inflammatory response are suspected as mediators of some of the pathological sequelae occurring as a result of spinal cord injury. Here we report temporal and regional increases of the NMDA receptor agonist, quinolinic acid (QUIN), in an experimental model of spinal contusio...

journal_title：Brain research

authors： Popovich PG,Reinhard JF Jr,Flanagan EM,Stokes BT

更新日期：1994-01-07 00:00:00

abstract：:Abdominal musculature participates in generating a large number of behaviors and protective reflexes, although each abdominal muscle is frequently activated differentially during particular motor responses. For example, rectus abdominis has been reported to play less of a role in respiration than other abdominal muscl...

journal_title：Brain research

authors： Billig I,Hartge K,Card JP,Yates BJ

更新日期：2001-08-31 00:00:00

abstract：:Neuropeptide Y (NPY) presynaptically inhibits excitatory transmission in area CA1 of rat hippocampus. As postsynaptic NPY receptors in certain other tissues have been shown to be coupled to G-proteins, we have tested the hypothesis that the hippocampal NPY effects are also mediated by G-proteins. Pretreatment of rats ...

journal_title：Brain research

authors： Colmers WF,Pittman QJ

更新日期：1989-09-25 00:00:00

abstract：:Equivalent antiinflammatory doses of steroids including betamethasone, methylprednisolone and dexamethasone were administered in the neonatal period in a rat model. In situ cell death in hippocampus quantified by Terminal Deoxynucleated Transferase Nick-End Labeling and on ratio of brain to body weight was investigate...

journal_title：Brain research

authors： Duksal F,Kilic I,Tufan AC,Akdogan I

更新日期：2009-01-23 00:00:00

abstract：:Substance P (SP) and neurokinin A (NKA), two coexisting neuropeptides of the tachykinin family, stimulated the basal (5 mM K+) and evoked (40 mM K+) release of [3H]5-HT (5-hydroxytryptamine) from tissue slices of the rat cerebral cortex. Spantide ([DArg1,-DTrp7,9,Leu11]SP; 10(-5) M) inhibited the effects of SP but pot...

journal_title：Brain research

authors： Iverfeldt K,Solti M,Bartfai T

更新日期：1990-01-08 00:00:00

abstract：:An immunohistochemical investigation of the bovine pineal gland was performed using both a rabbit polyclonal antibody and a rat monoclonal antibody against choline acetyltransferase (ChAT). A network of ChAT-immunoreactive (IR) nerve fibers was located throughout the pineal gland, both in the perivascular spaces and b...

journal_title：Brain research

authors： Phansuwan-Pujito P,Mikkelsen JD,Govitrapong P,Møller M

更新日期：1991-04-05 00:00:00

abstract：:Serial ion-exchange and high-performance liquid chromatography separations were employed for the tissue extraction and purification of kynurenic acid (KYNA). Subsequently, the compound isolated from postmortem human brain tissue was unequivocally identified as KYNA by nuclear magnetic resonance and mass spectrometric ...

journal_title：Brain research

authors： Turski WA,Nakamura M,Todd WP,Carpenter BK,Whetsell WO Jr,Schwarcz R

更新日期：1988-06-28 00:00:00

abstract：:The interpeduncular nucleus (IPN) was stimulated electrically while single-cell activity was recorded in the nucleus raphe magnus (NRM) of rats under pentobarbital anesthesia. Two classes of NRM cell were examined, those inhibited (off-cells) and those excited (on-cells) by noxious mechanical skin stimulation. Off-cel...

journal_title：Brain research

authors： Hentall ID,Budhrani VM

更新日期：1990-07-09 00:00:00

abstract：:We found that local perfusion of COA-Cl (0.1, 0.4, or 1.0 mM) into the dorsal striatum of living mice produced a significant and dose-dependent increase in extracellular DA levels, with the highest dose of 1.0 mM COA-Cl producing an approximately 5-fold increase in DA. Consistent with in vivo findings, 0.1 and 0.2 mM ...

journal_title：Brain research

authors： Jamal M,Tsukamoto I,Takata M,Ito A,Tanaka N,Miki T,Takakura A,Ameno K,Kubota Y,Konishi R,Kinoshita H

更新日期：2019-03-01 00:00:00

abstract：:Although nitric oxide (NO) has been shown to play an important role in the pathophysiology of cerebral ischemia, its contribution to the pathogenesis of experimentally induced thromboembolic stroke is unknown. In this study, we pharmacologically manipulated NO levels in the acute post-thrombotic stage and determined t...

journal_title：Brain research

authors： Stagliano NE,Dietrich WD,Prado R,Green EJ,Busto R

更新日期：1997-06-06 00:00:00