Defective 'gut processing' of gliadin in mice with graft-versus-host enteropathy.

abstract：BACKGROUND:Egg allergy is one of the most common food allergies in children. The standard therapy for egg allergy is strict avoidance. Yet, there is considerable clinical and scientific interest in primary or secondary prevention. A major drawback of oral tolerance (OT) induction protocols, however, is the possibility ...

journal_title：International archives of allergy and immunology

authors： Hacini-Rachinel F,Vissers YM,Doucet-Ladevéze R,Blanchard C,Demont A,Perrot M,Panchaud A,Prioult G,Mercenier A,Nutten S

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Chronic urticaria is associated with an immune dysregulation usually mediated by T lymphocytes. Recently, Th17 and Tc17 have been implicated in autoimmune diseases; however, their role in urticaria is not clear yet. METHODS:For the study we recruited 20 patients [10 of them had autoreactive chronic spontane...

journal_title：International archives of allergy and immunology

authors： Lopes A,Machado D,Pedreiro S,Henriques A,Silva I,Tavares B,Inácio MJ,Chieira C,Martinho A,Pais ML,Pereira C,Paiva A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:To elucidate the usefulness of antigen-specific immunotherapy based on oral vaccination with an edible part of the plant, we examined the effect of transgenic (Tg) rice seeds expressing an immunodominant fragment of the group 1 antigen of Dermatophagoides pteronyssinus (Der p 1) on a murine model of asthma. ...

journal_title：International archives of allergy and immunology

authors： Suzuki K,Kaminuma O,Yang L,Motoi Y,Takai T,Ichikawa S,Okumura K,Ogawa H,Mori A,Takaiwa F,Hiroi T

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Hereditary angioedema (HAE) with C1 inhibitor (C1-INH) deficiency is a rare autosomal dominant disease. Although the first symptoms can appear in childhood, the diagnosis's delay has a strong impact on the patient's quality of life. We analyzed clinical and laboratory characteristics and the drug therapy o...

journal_title：International archives of allergy and immunology

authors： Araújo-Simões J,Boanova AGP,Constantino-Silva RN,Fragnan NTML,Pinto JA,Minafra FG,Gonçalves RF,Valle SRD,Alonso MLO,Dortas SD,Goudouris ES,Rêgo-Silva AM,Marques MM,Serpa FS,Chong-Neto HJ,Nelson RF,Mansour E,Moreira IF,

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND:There is no information whether galectin-9 (a novel eosinophil chemoattractant) was associated with pathogenesis of eosinophilic disorders. METHODS:We assessed the expression of galectin-9 with imunostaining and in situ hybridization both in the lesion of angiolymphoid hyperplasia with eosinophilia, and per...

journal_title：International archives of allergy and immunology

authors： Saita N,Goto E,Yamamoto T,Cho I,Tsumori K,Kohrogi H,Maruo K,Ono T,Takeya M,Kashio Y,Nakamura K,Hirashima M

更新日期：2002-05-01 00:00:00

abstract：:The role of CD8+ T cells in the regulation of IgE was investigated by in vivo CD8+ T-cell depletion. Following intraperitoneal immunization with ovalbumin (OVA), OVA-specific T cell responses were first detected in the draining lymph nodes (LN) and subsequently in the spleen. In vitro depletion of LN CD8+ cells reduce...

journal_title：International archives of allergy and immunology

authors： Holmes BJ,MacAry PA,Kemeny DM

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Anti-inflammatory therapy is a logical approach to slowing the inevitable lung function deterioration in cystic fibrosis (CF) patients. This study's aim was to evaluate inflammatory markers and disease progression in paediatric CF patients chronically treated with azithromycin or low-dose prednisolone. METH...

journal_title：International archives of allergy and immunology

authors： Shmarina G,Pukhalsky A,Avakian L,Semykin S,Pukhalskaya D,Alioshkin V

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:House dust mite contains several allergen components and causes perennial allergy. Lately, a new major allergen, Der p 23, was described with relatively high sensitization rates in different European Countries. In addition, Der p 23 is supposed to cause asthmatic disease. OBJECTIVE:We would like to questi...

journal_title：International archives of allergy and immunology

authors： Eder K,Becker S,Gellrich D,Zieglmayer P,Gröger M

更新日期：2020-01-01 00:00:00

abstract：:The last decade has seen the rapid development of research investigating the mechanisms of apoptosis in a variety of experimental systems. Among the multitude of changes observed in apoptotic cells, chromatin cleavage is considered a biochemical hallmark of apoptosis. Chromatin fragmentation is an enzymatic process wh...

journal_title：International archives of allergy and immunology

authors： Zhivotovsky B,Wade D,Nicotera P,Orrenius S

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Basophils and mast cells are important initiator/effector cells capable of rapidly responding to IgE-mediated stimulation, but the precise mechanisms regulating their functions in vivo have not been fully identified. In this study, we assessed whether low levels of antigen can modulate activation of basophil...

journal_title：International archives of allergy and immunology

authors： Koketsu R,Yamaguchi M,Suzukawa M,Tanaka Y,Tashimo H,Arai H,Nagase H,Matsumoto K,Saito H,Ra C,Yamamoto K,Ohta K

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Recent work indicates that subcutaneous specific immunotherapy induces specific T-cell anergy, a shift in the TH1/TH2 ratio, and antibody production in favor of IgG4. There are few data on sublingual immunotherapy (SLIT), especially in children. METHODS:We assessed the proliferation of peripheral blood mono...

journal_title：International archives of allergy and immunology

authors： Rolinck-Werninghaus C,Kopp M,Liebke C,Lange J,Wahn U,Niggemann B

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Allergic bronchopulmonary aspergillosis (ABPA) develops in the presence of predisposing conditions such as asthma and cystic fibrosis. Even ABPA accompanied by asthma is often complicated by chronic Pseudomonas aeruginosa or nontuberculous mycobacterial infection of the lower respiratory tract, rendering tre...

journal_title：International archives of allergy and immunology

authors： Tomomatsu K,Oguma T,Baba T,Toyoshima M,Komase Y,Taniguchi M,Asano K,Japan ABPM Research Program.

更新日期：2020-01-01 00:00:00

abstract：:We investigated the effects of KW-4679, an antiallergic drug, on the development of bronchial hyperresponsiveness, airway inflammation and early and late asthmatic responses following aerosol antigen challenge in guinea pigs actively sensitized by the inhalation of aerosolized ovalbumin. Pretreatment with KW-4679 (10 ...

journal_title：International archives of allergy and immunology

authors： Ohmori K,Ishii H,Sasaki Y,Ikemura T,Manabe H,Kitamura S

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Aspirin-intolerant asthma (AIA) is a clinical syndrome characterized by acute bronchoconstriction following the ingestion of aspirin. Solute carrier family 22, member 2 (SLC22A2), also known as organic cation transporter 2 (OCT2), is predominantly expressed in the luminal membrane of airway epithelial cells ...

journal_title：International archives of allergy and immunology

authors： Park TJ,Kim JH,Bae JS,Park BL,Cheong HS,Chun JY,Lee JS,Kim JY,Pasaje CF,Cho SH,Uh ST,Kim MK,Choi IS,Koh IS,Park CS,Shin HD

更新日期：2011-01-01 00:00:00

abstract：:Allergens from the pollen of Parthenium hysterophorus (American feverfew), responsible for high incidence of allergic rhinitis, were found by immunoprint analysis to be localized on the surface of the pollen grains. The allergens were released very rapidly when extracted in vitro. The allergenic activity of the rapid ...

journal_title：International archives of allergy and immunology

authors： Gupta N,Sriramarao P,Kori R,Rao PV

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:The cytokine transforming growth factor-beta(TGF-beta) has important regulatory roles in the immune system. To investigate the role of intact TGF-beta signaling during the contact hypersensitivity (CHS) response to a respiratory allergen, we exposed Smad3-/- mice to topical trimellitic anhydride (TMA). METH...

journal_title：International archives of allergy and immunology

authors： Anthoni M,Fyhrquist N,Lehtimäki S,Alenius H,Wolff H,Lauerma A

更新日期：2010-01-01 00:00:00

abstract：:Recent data suggest that stem cell factor (SCF or c-kit ligand, KL) is a major regulator of human mast cells (MCs). In the present study, MCs derived from the lung (n = 8), uterus (n = 14) and heart (n = 4) were analyzed for expression of c-kit receptor and for responses to recombinant SCF. MCs of all organs tested we...

journal_title：International archives of allergy and immunology

authors： Sperr WR,Czerwenka K,Mundigler G,Müller MR,Semper H,Klappacher G,Glogar HD,Lechner K,Valent P

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Allergic conjunctivitis is characterized by itchy, watery and swollen eyes which occur in response to exposure to seasonal or environmental allergens. The early phase reaction of allergic conjunctivitis is primarily mediated by mast cell degranulation while the late phase reaction is driven by Th2 cells and ...

journal_title：International archives of allergy and immunology

authors： Stebbins KJ,Broadhead AR,Musiyenko A,Barik S,Scott JM,Truong YP,Stearns BA,Hutchinson JH,Prasit P,Evans JF,Lorrain DS

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:In some subjects, specific foods trigger anaphylaxis when exercise follows ingestion (specific food-dependent exercise-induced anaphylaxis, FDEIAn). Skin test and/or RAST positivity to foods suggest an IgE-mediated pathogenic mechanism. Others suffer from anaphylaxis after all meals followed by exercise, reg...

journal_title：International archives of allergy and immunology

authors： Romano A,Di Fonso M,Giuffreda F,Papa G,Artesani MC,Viola M,Venuti A,Palmieri V,Zeppilli P

更新日期：2001-07-01 00:00:00

abstract：:The aim of this study was to assess the relevance of immunoinflammatory markers on the response to short acting beta(2)-agonist in acute asthma exacerbation. Thus, we measured serum eosinophil cationic protein (ECP) levels and sIL-2R at acute exacerbation in 52 adult patients with atopic asthma, and assessed forced ex...

journal_title：International archives of allergy and immunology

authors： Di Lorenzo G,Pacor ML,Morici G,Drago A,Esposito-Pellitteri M,Candore G,Lo Bianco C,Caruso C

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Food allergy to wheat-derived foodstuffs is on the rise. Tri a 14, a wheat flour lipid transfer protein (LTP) allergen, has been described as a major allergen associated with baker's asthma and wheat food allergy. Cross-reactivity among LTP allergens leads to the so-called 'LTP syndrome'. METHODS:Eight adul...

journal_title：International archives of allergy and immunology

authors： Palacin A,Bartra J,Muñoz R,Diaz-Perales A,Valero A,Salcedo G

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:A number of different molecules are known to be involved in the signal pathway to release histamine from mast cells, among which arachidonic acid (AA) is one of the key mediators. On the other hand, we found that the application of compound 48/80, a typical histamine liberator, generated superoxide in mast c...

journal_title：International archives of allergy and immunology

authors： Sakaguchi M,Fukuishi N,Teramoto K,Miyazaki M,Huh NH,Namba M,Akagi M

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:In a subgroup of patients with atopic eczema (AE), aeroallergens are relevant eliciting factors. The atopy patch test (APT) was proposed as inflammation model for AE. OBJECTIVE:It was the aim of this study to investigate the effect of pretreatment with 1% pimecrolimus cream (Elidel) on the APT and skin pric...

journal_title：International archives of allergy and immunology

authors： Weissenbacher S,Traidl-Hoffmann C,Eyerich K,Katzer K,Braeutigam M,Loeffler H,Hofmann H,Behrendt H,Ring J,Darsow U

更新日期：2006-01-01 00:00:00

abstract：:Antibody response after immunization with surface-coupled ovalbumin (OVA) of liposomes was investigated in mice. OVA was coupled to the surface of liposome via amino groups using glutaraldehyde. OVA-liposome conjugate induced a significant anti-OVA IgG antibody production in mice. However, no IgE antibody production s...

journal_title：International archives of allergy and immunology

authors： Naito S,Horino A,Nakayama M,Nakano Y,Nagai T,Mizuguchi J,Komuro K,Uchida T

更新日期：1996-03-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to evaluate the effectiveness of specific immunotherapy (SIT) management with allergoids in children with allergic asthma by monitoring changes in clinical parameters and inflammatory markers in exhaled breath. METHODS:The study population included 43 patients (24 males) of 6-14 ...

journal_title：International archives of allergy and immunology

authors： Lozano J,Cruz MJ,Piquer M,Giner MT,Plaza AM

更新日期：2014-01-01 00:00:00

abstract：:Platelet-activating factor (PAF)-induced augmentation of spontaneous differentiation into eosinophil-lineage cells from hematopoietic precursor cells was found among human umbilical cord blood mononuclear cells (CBMCs). This ability of PAF to augment eosinophil production was significantly (p < 0.01) inhibited by the ...

journal_title：International archives of allergy and immunology

authors： Saito H,Koshio T,Yanagihara Y,Akiyama K,Shida T

更新日期：1993-01-01 00:00:00

abstract：:We investigated the in vitro adhesion of 51Cr-labeled lymphocytes to cultured brain endothelial cells and the in vivo expression of intercellular adhesion molecule-1 (ICAM-1) on cerebral endothelial cells in a rat model of experimental allergic encephalomyelitis (EAE) before and after treatment with lipopolysaccharide...

journal_title：International archives of allergy and immunology

authors： Matsuda M,Tsukada N,Miyagi K,Yanagisawa N

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:Secretory phospholipases A(2) (sPLA(2)) are an emerging class of mediators of inflammation. These enzymes are released in vivo in patients with systemic inflammatory diseases and allergic disorders. sPLA(2)s may activate inflammatory cells by both enzymatic and nonenzymatic mechanisms. The aim of this study ...

journal_title：International archives of allergy and immunology

authors： Triggiani M,Granata F,Petraroli A,Loffredo S,Frattini A,Staiano RI,Monaco G,Marone G

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Disturbed cytokine production is thought to govern inflammation in asthma, which, in its turn, may lead to uncontrolled disease. The aim of this study was to assess the relationship between cytokine production from blood leucocytes and the level of asthma control. METHODS:We compared the production of inter...

journal_title：International archives of allergy and immunology

authors： Manise M,Schleich F,Quaedvlieg V,Moermans C,Henket M,Sele J,Corhay JL,Louis R

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The hemagglutinin (HA) of influenza viruses is one of the major targets of the humoral response. The role of serum antibody to HA in the protection against infection has been demonstrated by long-standing observation. In previous studies, we suggested that an epitope vaccine might be a new strategy against t...

journal_title：International archives of allergy and immunology

authors： Lu Y,Ding J,Liu W,Chen YH

更新日期：2002-03-01 00:00:00