Abstract:
:In a previous investigation of the rDNA region in Tetrahymena pyriformis mitochondrial DNA, we identified a putative tRNA(Met) gene [Heinonen et al. (1987) J. Biol. Chem. 262, 2879-2887]. On the basis of Northern hybridization analyses, we suggested that this gene is expressed, even though the resulting tRNA would be unusually small and have an atypical dihydrouridine stem-loop domain. We report here the complete nucleotide sequence and post-transcriptional modification pattern of this tRNA(Met), confirming its predicted primary structure and supporting the view that this structurally aberrant species functions in translation in T. pyriformis mitochondria.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Schnare MN,Greenwood SJ,Gray MWdoi
10.1016/0014-5793(95)00179-dsubject
Has Abstractpub_date
1995-03-27 00:00:00pages
24-8issue
1eissn
0014-5793issn
1873-3468pii
0014-5793(95)00179-Djournal_volume
362pub_type
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