Abstract:
:The relationship between the antioxidant effects of reduced coenzyme Q10 (ubiquinol, UQH2) and vitamin E (alpha-tocopherol) was investigated in beef heart submitochondrial particles in which lipid peroxidation was initiated by incubation with ascorbate + ADP-Fe3+. These effects were examined after extraction of coenzyme Q10 (UQ-10) and vitamin E from the particles and reincorporation of the same components alone or in combination. The results show that UQH2 efficiently inhibits lipid peroxidation even when vitamin E is absent. It is concluded that UQH2 can inhibit lipid peroxidation directly, without the mediation of vitamin E.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Forsmark P,Aberg F,Norling B,Nordenbrand K,Dallner G,Ernster Ldoi
10.1016/0014-5793(91)80720-nsubject
Has Abstractpub_date
1991-07-08 00:00:00pages
39-43issue
1eissn
0014-5793issn
1873-3468pii
0014-5793(91)80720-Njournal_volume
285pub_type
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