Abstract:
:Cell-substratum adhesion of rat hepatocytes was inhibited by antisera raised against plasma membranes of liver (anti-liver antiserum) and Morris hepatoma 7777 (anti-hepatoma antiserum). Similar concentrations of both antisera inhibited adhesion on collagen. Anti-liver antiserum also inhibited the adhesion of hepatocytes on plastic, whereas anti-hepatoma antiserum was only able to inhibit the adhesion on collagen completely. These results suggest the existence of at least two different adhesion-involved molecules. Cells adhere to plastic by means of both molecules, whereas adhesion on collagen is mediated by only one of them. The results further suggest that hepatoma cells lost the molecule involved in adhesion on plastic.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Neumeier R,Dethlefs U,Reutter Wdoi
10.1016/0014-5793(84)80254-9subject
Has Abstractpub_date
1984-03-26 00:00:00pages
241-4issue
2eissn
0014-5793issn
1873-3468pii
0014-5793(84)80254-9journal_volume
168pub_type
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