Abstract:
:A riboflavin carrier protein has been purified from human pregnancy and umbilical cord sera by affinity chromatography and fast protein liquid chromatography. This protein has a similar molecular weight to the chicken egg riboflavin carrier protein and shares other physicochemical properties, such as pI and riboflavin binding characteristics, with the avian counterpart. A high degree of immunological cross-reactivity is observed between the human and avian riboflavin binding proteins indicating the extensive conservation of this protein throughout evolution.
journal_name
Biosci Repjournal_title
Bioscience reportsauthors
Visweswariah SS,Adiga PRdoi
10.1007/BF01119773subject
Has Abstractpub_date
1987-07-01 00:00:00pages
563-71issue
7eissn
0144-8463issn
1573-4935journal_volume
7pub_type
杂志文章abstract::The proton conductance of the mitochondrial inner membrane can be quantified by applying Ohm's law to the experimentally determined protonmotive force and the proton current flowing around the proton circuit in the absence of ATP synthesis or ion transport. This last parameter is derived from the rate of State 4 respi...
journal_title:Bioscience reports
pub_type: 杂志文章,评审
doi:10.1023/a:1027376426860
更新日期:1997-06-01 00:00:00
abstract::ATP-dependent chromatin remodeling proteins use the energy released from ATP hydrolysis to reposition nucleosomes in DNA-dependent processes. These proteins are classified as SF2 helicases. SMARCAL1, a member of this protein family, is known to modulate both DNA repair and transcription by specifically recognizing DNA...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20180568
更新日期:2018-06-27 00:00:00
abstract::CXCL8, a member of CXC chemokines, was constitutively expressed in many types of human cancers, and its overexpression has been shown to play a critical role in promoting tumorigenesis. The purpose of the present study was to determine CXCL8 expression in a commercial human liver tissue microarray, and elucidate the e...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20201169
更新日期:2020-08-28 00:00:00
abstract:OBJECTIVE:To study the correlation between adenomatous polyposis coli (APC) gene 3' untranslated region (UTR) single nucleotide polymorphisms (SNPs) and their interactions with environmental factors and the risk of colorectal cancer (CRC) in a Chinese Han population. METHODS:Genotypes of APC gene 3'UTR rs1804197, rs41...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20192429
更新日期:2020-03-27 00:00:00
abstract::Gram negative bacterial infection is a leading cause of fatality and is attributed, at least in part, to the bacteria's capacity to persist in the host in spite of appropriate antibiotic therapy. It has been suggested that bacteria evade antibiotics by hiding within host cells. We sought to investigate this important ...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1023/a:1020216323271
更新日期:1999-10-01 00:00:00
abstract:AIM:To explore the prognostic value of clusterin (CLU) in hepatocellular carcinoma (HCC) patients treated with oxaliplatin (OXA). METHODS:Relative expression of plasma CLU mRNA was examined via fluorescence quantitative real-time PCR (qRT-PCR), and CLU protein level in tissue samples was detected through immunohistoch...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20200071
更新日期:2020-02-28 00:00:00
abstract::Peptide sequencing of the complement system regulatory protein, factor H, permitted the synthesis of a mixed sequence oligonucleotide probe. Human liver cDNA libraries were screened and factor H-specific clones selected. No full-length clone was obtained, but the largest available clone, R2a, was found to encode the C...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1007/BF01124790
更新日期:1987-03-01 00:00:00
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journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1007/BF01115155
更新日期:1986-03-01 00:00:00
abstract::The growth arrest special 5 (GAS5), as a research hotspot of long noncoding RNAs (lncRNAs), has been reported to be associated with colorectal cancer (CRC). However, the association between polymorphisms in GAS5 and the risk of CRC was not clear. In the present study, a case-control study in 1078 CRC patients and 1175...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20190091
更新日期:2019-04-16 00:00:00
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journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20200995
更新日期:2020-07-31 00:00:00
abstract::An ontogenetic study of the effect of various neurohormones and other activators on adenylate cyclase systems was carried out using cultures of cells from 15-d-old embryonic mouse brain. Dopamine stimulated the enzyme activity at earlier culture ages (i.e. 4 and 10 d) but had little stimulatory effect at later ages (i...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1007/BF01117073
更新日期:1985-07-01 00:00:00
abstract::This paper presents a short review of our contribution to the knowledge of the structure and function of human C1r, the activation unit of C1, the first component of the classical pathway of complement. On the basis of the domain structure of C1r, a model accounting for its autolytic activation mechanism is proposed. ...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1007/BF01119894
更新日期:1985-10-01 00:00:00
abstract::Many clinical experiments and studies have demonstrated that traditional Chinese medicines possess the capacity for being used in anti-sepsis. In this paper, we screened 78 herbs based on biosensor technology by targeting of lipid A. Terminaliachebula Retz was found to possess the highest capability of binding lipid A...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20080158
更新日期:2009-10-06 00:00:00
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journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20192826
更新日期:2020-03-27 00:00:00
abstract::Western blotting was used as a powerful alternative to immunoprecipitation for the detection of the simian virus 40 (SV40) large tumor (T) antigen. After resolution by electrophoresis on a SDS-polyacrylamide gel of a [35S]methionine labeled crude extract from SV40 infected monkey kidney cells, the separated proteins w...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1007/BF01117060
更新日期:1985-02-01 00:00:00
abstract::Long non-coding RNAs (lncRNAs) act as crucial modulators during the development of diverse cancers. Although various types of lncRNAs in prostate cancer (PCa) have been explored, quantities of lncRNAs still wait to be exploited. The present study is to probe the functions and mechanism of lncRNA HOXA cluster antisense...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20193287
更新日期:2020-08-28 00:00:00
abstract::Resistance to chemotherapy is one of main obstacles in the treatment of colorectal cancer (CRC). However, the mechanisms are still unclear, and the treatment options are still limited. miR-543 has been indicated to act as an oncogene in some cancers, but its function in regulating chemoresistance has not been consider...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20190249
更新日期:2019-03-22 00:00:00
abstract::Fatty-acid synthesis has been measured in vivo with 3H2O in cafeteria-fed rats exhibiting diet-induced thermogenesis. Synthesis was decreased in brown adipose tissue, the liver, white adipose tissue, and the carcass of the cafeteria-fed animals compared to rats fed the normal stock diet. Whole-body synthesis was also ...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1007/BF01122453
更新日期:1983-03-01 00:00:00
abstract::Accumulating evidence demonstrates that long non-coding RNAs (LncRNAs) play important roles in regulating gene expression and are involved in various cancers, including colorectal cancer (CRC). However, LncRNA profiles in CRC remain largely unknown. The present study aims to find the key LncRNA associated with CRC and...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20160048
更新日期:2016-05-06 00:00:00
abstract::Diabetic neuropathy (DNP) is the most common complication of diabetes mellitus affecting approximately 50% of diabetes patients. Studying the effect of potential drugs with antioxidant properties and minimal toxicities on neural cells may lead to the development of new and safe pharmacotherapy. Dexmedetomidine (DEX), ...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20200394
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abstract::Fasudil is a derivative of 5-isoquinoline sulfonamide, which is a Rho kinase inhibitor, a wide range of pharmacological effects. Fasudil has been shown to attenuate kidney injury caused by certain substances. In the present study, metabolomic analysis of mouse kidney tissues ultra-performance liquid chromatography/qua...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20192940
更新日期:2019-11-29 00:00:00
abstract::Osteoarthritis (OA) is the most common form of arthritis, and connective tissue growth factor (CTGF) is found to be up-regulated in adjacent areas of cartilage surface damage. CTGF is present in osteophytes of late stage OA. In the present study, we have reviewed association of CTGF in the development and progression ...
journal_title:Bioscience reports
pub_type: 杂志文章,评审
doi:10.1042/BSR20191374
更新日期:2019-07-18 00:00:00
abstract::Background: There is a clinical need for the use of engineered adipose tissue in place of surgical reconstruction. We previously found that the external volume expansion (EVE) device increased special cell clusters in well-vascularized connective stroma during adipose regeneration. However, the origin of these cell cl...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20181776
更新日期:2019-02-26 00:00:00
abstract::The present study was designed to investigate the protective effect of moracin on primary culture of nucleus pulposus cells in intervertebral disc and explore the underlying mechanism. Moracin treatment significantly inhibited the LPS-induced inflammatory cytokine accumulation (IL-1β, IL-6 and TNF-α) in nucleus pulpos...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20191673
更新日期:2019-12-20 00:00:00
abstract::In the present study, we aimed to examine whether SET domain-containing methyltransferases are up-regulated in different classes of renal cell carcinoma. We immunoblotted against SET domain and quantified the expression of these modular domains. Furthermore, we examined the expression of Rad51, the key protein that co...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20160122
更新日期:2016-06-30 00:00:00
abstract::We have shown previously that Escherichia coli K92 produces two different capsular polymers known as CA (colanic acid) and PA (polysialic acid) in a thermoregulated manner. The complex Rcs phosphorelay is largely related to the regulation of CA synthesis. Through deletion of rscA and rscB genes, we show that the Rcs s...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20130018
更新日期:2013-05-24 00:00:00
abstract::Cervical cancer (CC) is ranked as the fourth most common cancer that occurs in women universally, which normally causes pain in the lower belly. Plenty of studies have stated that the expression of long non-coding RNAs (lncRNAs) is linked to the cellular development of many kinds of cancers. DSCAM-AS1 has been reporte...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20192061
更新日期:2020-01-31 00:00:00
abstract::This study is part of an attempt to understand the role of specific cellular activities in the bone resorptive process. Experiments were performed whereby known pharmacological agents were used to inhibit individual modes of osteoclastic activity, such as motility and secretion. The effects of such treatments on bone ...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1007/BF01116615
更新日期:1990-12-01 00:00:00
abstract::Hepatocellular carcinoma (HCC) has been one of the most highly lethal cancers. The acquisition of drug resistance accounts for the majority of poor effects of chemotherapy in HCC. Non-coding RNAs (ncRNAs) including miRNAs, long ncRNAs (lncRNAs), and circular RNA (circRNA) have been well-documented to participate in ca...
journal_title:Bioscience reports
pub_type: 杂志文章,评审
doi:10.1042/BSR20180915
更新日期:2018-10-09 00:00:00
abstract::Mycoplasma pneumoniae is one of the most common pathogenic causes of community-acquired pneumonia. Hydrogen sulfide, alanine, and pyruvate producing enzyme (HapE) is a recently discovered M. pneumoniae virulence factor that can produce H2S to promote erythrocyte lysis. However, other cytotoxic effects of HapE have not...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20182201
更新日期:2019-01-18 00:00:00