The Mycoplasma pneumoniae HapE alters the cytokine profile and growth of human bronchial epithelial cells.

abstract：:Sulphate efflux from human placental microvillus membrane vesicles was inhibited by external DIDS (KI congruent to 10(-6) M). This inhibition was partially reversed on addition of the translocated substrates sulphate or selenate to the external medium: selenite which is not translocated does not protect against DIDS i...

journal_title：Bioscience reports

authors： Shennan DB,Boyd CA

更新日期：1986-10-01 00:00:00

abstract：:Secretion of high molecular weight (HMW) adiponectin is dependent on post-translational modification (PTM) of conserved lysines in the collagenous domain. The present study aims to characterize the enzymes responsible for the PTM of conserved lysines which leads to HMW adiponectin secretion, and to define its signific...

journal_title：Bioscience reports

authors： Webster JA,Yang Z,Kim YH,Loo D,Mosa RM,Li H,Chen C

更新日期：2017-05-17 00:00:00

abstract：:The present study describes the enzymatic properties and molecular identification of 5'-nucleotidase in soluble and microsomal fractions from rat cardiac ventricles. Using AMP as a substrate, the results showed that the cation and the concentration required for maximal activity in the two fractions was magnesium at a ...

journal_title：Bioscience reports

authors： Pochmann D,Innocente AM,Cotomacci G,Barreto-Chaves ML,Sarkis JJ

更新日期：2008-10-01 00:00:00

abstract：:Long noncoding RNA (lncRNA) differentiation antagonizing nonprotein coding RNA (DANCR) plays important regulatory roles in many solid tumors. However, the effect of DANCR in glioma progression and underlying molecular mechanisms were not entirely explored. In the present study, we determined the expression of DANCR in...

journal_title：Bioscience reports

authors： Xu D,Yu J,Gao G,Lu G,Zhang Y,Ma P

更新日期：2018-02-02 00:00:00

abstract：:Ovarian cancer is a highly lethal cancer in females. Therefore, it is necessary to explore effective biomarkers for the diagnosis and prognosis of the disease. Stratifin (SFN) is a cell cycle checkpoint protein that has been reported to be involved in oncogenesis. Our studies detected the expression of SFN in ovarian ...

journal_title：Bioscience reports

authors： Hu Y,Zeng Q,Li C,Xie Y

更新日期：2019-05-02 00:00:00

abstract：:Chemical and physical stimuli trigger a cutaneous response by first inducing the main epidermal cells, keratinocytes, to produce specific mediators that are responsible for the initiation of skin inflammation. Activation modulates cell communication, namely leucocyte recruitment and blood-to-skin extravasation through...

journal_title：Bioscience reports

authors： Franchi J,Marteau C,Crola da Silva C,Mitterrand M,André P,Kieda C

更新日期：2008-02-01 00:00:00

abstract：:Mouse Mex3c encodes RNA-binding proteins of variant length through alternative splicing. Its mutation results in multiple defects including growth retardation, perturbed energy balance, and defective antiviral innate immunity. Here we report that Mex3c mutation affects mammary gland development and lactation in female...

journal_title：Bioscience reports

authors： Du Y,Sun D,Li Y

更新日期：2020-12-23 00:00:00

abstract：:Imipramine and clorgyline, at concentrations of 0.002 M, inhibit the respiration of brain tissue by 82 and 71 per cent respectively, while chloropromazine and tranylcypromine, at concentrations of 0.01 M, inhibit it about 25 per cent. Deprenyl and amphetamine at a concentration of 0.002 M inhibit brain tissue respirat...

journal_title：Bioscience reports

authors： Nag M,Nandi N

更新日期：1991-02-01 00:00:00

abstract：:Osteoarthritis (OA) is one of the most common chronic joint disease. Long non-coding RNAs (lncRNAs) have been confirmed to play important roles in a variety of diseases including OA. However, the underlying mechanism of lncRNA differentiation antagonizing non-protein coding RNA (DANCR) in OA has not been well elucidat...

journal_title：Bioscience reports

authors： Zhang L,Zhang P,Sun X,Zhou L,Zhao J

更新日期：2018-12-14 00:00:00

abstract：:Objective: We aimed to assess the possible relations between serum levels of macrophage migration inhibitory factor (MIF), a central cytokine of the innate immunity and inflammatory response, and benign paroxysmal positional vertigo (BPPV) risk and BPPV recurrence events.Methods: In the present study, 154 patients wit...

journal_title：Bioscience reports

authors： Cai HB,Duan L,Tian T,Li ZC,Zhao CC,Ge ZM

更新日期：2019-08-23 00:00:00

abstract：:Interleukins (ILs) are the most typical inflammatory and immunoregulatory cytokines. Evidences have shown that polymorphisms in ILs are associated with cerebral infarction risk. However, the results remain inconclusive. The present study was to evaluate the role of ILs polymorphisms in cerebral infarction susceptibili...

journal_title：Bioscience reports

authors： Wang J,Fan N,Deng Y,Zhu J,Mei J,Chen Y,Yang H

更新日期：2016-11-03 00:00:00

abstract：:Mitochondrial dysfunction causes a range of early-onset neurological diseases and contributes to neurodegenerative conditions. The mechanisms of neurological damage however are poorly understood, as accessing relevant tissue from patients is difficult, and appropriate models are limited. Hence, we assessed mitochondri...

journal_title：Bioscience reports

authors： Bird MJ,Wijeyeratne XW,Komen JC,Laskowski A,Ryan MT,Thorburn DR,Frazier AE

更新日期：2014-11-21 00:00:00

abstract：:The nature of certain forms of memory is discussed in relation to neural networks and REM sleep. ...

journal_title：Bioscience reports

authors： Crick F

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:Nasopharyngeal carcinoma (NPC) is a tumor that is commonly found in southern China. NPC has several risk factors, such as infection with the Epstein-Barr virus. However, we know little about the risk factors for eye metastasis (EM) in male patients with NPC. Serum lipids are well recognized as risk factors f...

journal_title：Bioscience reports

authors： Xie Z,Shao Y

更新日期：2020-06-26 00:00:00

abstract：:Having a better grasp of the molecular mechanisms underlying carcinogenesis and progression in osteosarcoma would be helpful to find novel therapeutic targets. Different types of cancers have presented abnormal expression of miRNA-101 (miR-101). Nevertheless, we still could not figure out what expression of miR-101 in...

journal_title：Bioscience reports

authors： Lin H,Zheng X,Lu T,Gu Y,Zheng C,Yan H

更新日期：2019-02-08 00:00:00

abstract：:An antibody was raised to the synthetic pentapeptide pGluHisProGlyLys which, in radioimmunoassay (RIA), could detect the pentapeptide at a level of 10 fmole per tube and exhibited less than 0.5 per cent cross reactivity with a series of related peptides. The RIA was used to demonstrate the presence of C-terminally ext...

journal_title：Bioscience reports

authors： Cockle SM,Smyth DG

更新日期：1986-06-01 00:00:00

abstract：:Conflicting opinions were recently expressed concerning the possible effect of alpha 2-adrenergic agonists upon cyclic AMP production in pancreatic islets. In the present study, clonidine inhibited glucose-induced insulin release from rat pancreatic islets, this inhibitory effect being abolished by idazoxan. Clonidine...

journal_title：Bioscience reports

authors： Garcia-Morales P,Dufrane SP,Sener A,Valverde I,Malaisse WJ

更新日期：1984-06-01 00:00:00

abstract：:MicroRNA-326 (miR-326) was reported to be dysregulated and involved in the progression of multiple cancers. However, the clinical significance, biological role and underlying mechanism of miR-326 in the carcinogenesis of breast cancer are still unclear. In the present study, we showed that miR-326 was down-regulated i...

journal_title：Bioscience reports

authors： Du Y,Shen L,Zhang W,Ding R,Li Q,Li S,Zhang H

更新日期：2019-07-29 00:00:00

abstract：:Amphiphilic anionic peptides have been used to enhance the efficiency of transfection by helping plasmids to escape from endosomes to the cytosol. It has been shown that efficiency of an eicosamers containing five glutamyl residues (E5), can be considerably enhanced either by transforming it into a dimer or by adding ...

journal_title：Bioscience reports

authors： Freulon I,Monsigny M,Midoux P,Mayer R

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Lung adenocarcinoma (LUAD) is the most frequent histological type of lung cancer, and its incidence has displayed an upward trend in recent years. Nevertheless, little is known regarding effective biomarkers for LUAD. METHODS:The robust rank aggregation method was used to mine differentially expressed genes...

journal_title：Bioscience reports

authors： Song Y,Tang W,Li H

更新日期：2021-01-29 00:00:00

abstract：:Neuroblastoma is the most common tumor in children, with a very poor prognosis. It is urgent to identify novel biomarkers to treat neuroblastoma, together with surgery, chemotherapy, and radiation. Human tripartite motif 59 (TRIM59), a member of the TRIM family, has been reported to participate in several human tumors...

journal_title：Bioscience reports

authors： Chen G,Chen W,Ye M,Tan W,Jia B

更新日期：2019-01-18 00:00:00

abstract：:Hippo pathway is a highly conservative signalling pathway related to the development of organisms, which has been demonstrated to be strongly linked to the tumorigenesis and tumour progression. As the major downstream effector of Hippo pathway, yes-associated protein (YAP), is a transcriptional activator of target gen...

journal_title：Bioscience reports

authors： Wang S,Ma K,Chen L,Zhu H,Liang S,Liu M,Xu N

更新日期：2016-09-29 00:00:00

abstract：:The hematopoietic cell kinase (HCK), a member of the Src family protein-tyrosine kinases (SFKs), is primarily expressed in cells of the myeloid and B lymphocyte lineages. Nevertheless, the roles of HCK in glioblastoma (GBM) remain to be examined. Thus, we aimed to investigate the effects of HCK on GBM development both...

journal_title：Bioscience reports

authors： Wang Z,Ying C,Zhang A,Xu H,Jiang Y,Lou M

更新日期：2020-06-26 00:00:00

abstract：:Many clinical experiments and studies have demonstrated that traditional Chinese medicines possess the capacity for being used in anti-sepsis. In this paper, we screened 78 herbs based on biosensor technology by targeting of lipid A. Terminaliachebula Retz was found to possess the highest capability of binding lipid A...

journal_title：Bioscience reports

authors： Yao J,Zheng JS,Fu W,Zheng J

更新日期：2009-10-06 00:00:00

abstract：:Immobilization of yeast mitochondrial RNA on nitrocellulose filters without prior alkali treatment revealed a low-MW RNA species (integral of 300 bases) which hybridizes specifically to the RNA coding strand of a DNA fragment BglII-HinfI at the 3' end of the COB-BOX gene. This RNA species (often a doublet) was found i...

journal_title：Bioscience reports

authors： Halbreich A,Grandchamp C,Foucher M

更新日期：1981-07-01 00:00:00

abstract：:Nonsmall cell lung cancer (NSCLC) is one of the most frequent malignancies worldwide. Long noncoding RNAs (LncRNAs) play critical roles in cancer initiation and progression. Previous studies have demonstrated that overexpression of cytoskeleton regulator RNA (CYTOR) predicates poor prognosis and promotes tumor progres...

journal_title：Bioscience reports

authors： Zhang J,Li W

更新日期：2018-12-18 00:00:00

abstract：:Accumulating evidence demonstrates that long non-coding RNAs (LncRNAs) play important roles in regulating gene expression and are involved in various cancers, including colorectal cancer (CRC). However, LncRNA profiles in CRC remain largely unknown. The present study aims to find the key LncRNA associated with CRC and...

journal_title：Bioscience reports

authors： Sun L,Xue H,Jiang C,Zhou H,Gu L,Liu Y,Xu C,Xu Q

更新日期：2016-05-06 00:00:00

abstract：:Phagocytosis by neutrophils, macrophages, and other professional phagocytes requires rapid remodeling of actin. Early phagosomes are surrounded by a rim of F-actin that is disassembled during phagosomoal maturation. Breakdown of periphagosomal F-actin and phagolysosome fusion are calcium dependent processes in neutrop...

journal_title：Bioscience reports

authors： Tejle K,Magnusson KE,Rasmusson B

更新日期：2002-10-01 00:00:00

abstract：:The kinetics of the fusion process between erythrocyte ghosts, as induced by Sendai virus, were readily revealed by a simple fluorescence procedure previously employed to characterize the fusion of viruses with biological membranes. The method relies on the relief of fluorescence selfquenching of the membrane-inserted...

journal_title：Bioscience reports

authors： Hoekstra D,Klappe K

更新日期：1986-11-01 00:00:00

abstract：:The effect that research on dopamine and other neutro trasmitters has on disciplines like neurology and psychiatry is described. ...

journal_title：Bioscience reports

authors： Carlsson A

更新日期：2001-12-01 00:00:00