Association between polymorphism in the promoter region of lncRNA GAS5 and the risk of colorectal cancer.

abstract：:Extracts from uterine cervical and body cancers, but not from benign tumor or intact tissues tested, were found to contain a growth-promoting activity which induced the proliferation of human endometrial fibroblasts. Exposure of cultured fibroblasts to the cancer extracts increased the rate of [3H]thymidine incorporat...

journal_title：Bioscience reports

authors： Imai A,Matsunami K,Iida K,Tamaya T

更新日期：1990-02-01 00:00:00

abstract：:Background: Many epidemiologic studies have explored the association between age at last birth (ALB) and the risk of epithelial ovarian cancer, but the results remain controversial. Methods: A literature search was performed in PubMed, Web of Science, China National Knowledge Infrastructure (CNKI) and WanFang Med Onli...

journal_title：Bioscience reports

authors： Wu Y,Sun W,Xin X,Wang W,Zhang D

更新日期：2019-09-13 00:00:00

abstract：:The present study estimates the effect of rivaroxaban on preventing deep vein thrombosis (DVT) in aged diabetics with femoral neck fractures after hip replacement. Our study consisted of 236 aged diabetics with femoral neck fractures, which were divided into the rivaroxaban and control groups. Reaction time (R time), ...

journal_title：Bioscience reports

authors： Zhang YM,Jiang X,Sun YS

更新日期：2017-06-21 00:00:00

abstract：:In the present study, we investigated the role of lncRNA SAMMSON in hepatocellular carcinoma (HCC). We found that SAMMSON was up-regulated in HCC tissues, and patients with high levels of SAMMSON in HCC tissues had significantly lower overall rate within 5 years after admission. miR-9-3p was down-regulated in HCC tiss...

journal_title：Bioscience reports

authors： Yang S,Cai H,Hu B,Tu J

更新日期：2019-07-05 00:00:00

abstract：:Although wasting marmoset syndrome (WMS) is one of the biggest problems facing captive marmoset colonies, the mechanisms underlying its pathogenesis remain unclear. In our clinical experience, it is difficult to cure WMS-affected marmosets with severe hypoalbuminemia. Thus, the mechanisms underlying hypoalbuminemia in...

journal_title：Bioscience reports

authors： Niimi K,Morishita H,Usui M,Ito R,Kurata S,Mataga N,Takahashi E

更新日期：2019-07-08 00:00:00

abstract：:Huaier Granule, a type of traditional Chinese biomedical preparation (TCBP), is considered to be a promising adjuvant therapy for breast cancer. Although an analysis of the published literature has been performed, the exact effects and safety of Huaier Granule remains controversial. Therefore, a wide-ranging systemati...

journal_title：Bioscience reports

authors： Yao X,Wu W,Qu K,Xi W

更新日期：2020-08-28 00:00:00

abstract：:The response to D-glucose (0-21 mM) was studied in neutrophil granulocytes from obese, hyperglycemic and hyperinsulinemic Umeå ob/ob mice and their lean, littermate controls in order to further elucidate the effects of in vivo and in vitro hyperglycemia on neutrophil function. Neutrophil random locomotion on glass and...

journal_title：Bioscience reports

authors： Oldenborg PA,Sehlin J

更新日期：1997-10-01 00:00:00

abstract：:Ca-ATPase activity in sarcoplasmic reticulum (SR) membranes isolated from skeletal muscles of the typical hibernator, the ground squirrel Spermophilus undulatus, is about 2-fold lower than that in SR membranes of rats and rabbits and is further decreased 2-fold during hibernation. The use of carbocyanine anionic dye S...

journal_title：Bioscience reports

authors： Malysheva AN,Storey KB,Lopina OD,Rubtsov AM

更新日期：2001-12-01 00:00:00

abstract：:Merremia vitifolia (Burm.f.) Hallier f., an ethnomedicinally important plant, used in the tribal areas to treat various ailments including fever, headache, eye inflammation, rheumatism, dysentery, jaundice and urinary diseases. The present study explored the biological efficacy of the aqueous fraction of M. vitifolia ...

journal_title：Bioscience reports

authors： Akter S,Jahan I,Khatun MR,Khan MF,Arshad L,Jakaria M,Haque MA

更新日期：2021-01-29 00:00:00

abstract：:Gold thioglucose and gold sodium thiomalate were shown to be potent activators of latent human leukocyte collagenase. No activation by auranofin was noted. The activation may proceed through the action of gold on the essential sulfhydryl groups of latent enzyme and, thereby, mimick the action of the known organomercur...

journal_title：Bioscience reports

authors： Sorsa T,Suomalainen K,Turto H,Lindy S

更新日期：1987-12-01 00:00:00

abstract：:In a study of Necturus gallbladder epithelium Benzel et al. (Benzel et al., 1980) found that low (0.2-1.2 microM) and higher concentrations (1.5 microM and more) of cytochalasin B (CB) caused an increase and decrease in the transepithelial electrical resistance (TER), respectively. Moreover, there were slight changes ...

journal_title：Bioscience reports

authors： Nybom P,Magnusson KE

更新日期：1996-08-01 00:00:00

abstract：:LGMD (limb-girdle muscular dystrophy) and CMD (congenital muscular dystrophy) are two common forms of neuromuscular disorders which are distinguishable by their age of onset but with probably a similar underlying pathway. In the present study, we report immunohistochemical, Western-blot and genetic analyses in a large...

journal_title：Bioscience reports

authors： Hadj Salem I,Kamoun F,Louhichi N,Rouis S,Mziou M,Fendri-Kriaa N,Makni-Ayadi F,Triki C,Fakhfakh F

更新日期：2011-04-01 00:00:00

abstract：:High-affinity binding of 3H-folate in Triton X-100 solubilized membranes of human liver displayed characteristics, e.g. apparent positive cooperativity, which are typical of specific folate binding. Ultrogel AcA 44 chromatography of solubilized membranes saturated with 3H-folate revealed a major peak of 100 kDa and a ...

journal_title：Bioscience reports

authors： Holm J,Hansen SI,Høier-Madsen M

更新日期：1991-06-01 00:00:00

abstract：:Transfer of Bomirski amelanotic melanoma cells from in vivo to in vitro growth conditions results in occurrence of rapid melanization in their cytoplasm. The melanized cells from primary cell culture initiate tumours in hamsters, which do not contain traces of melanin and resemble typical amelanotic melanoma. ...

journal_title：Bioscience reports

authors： Słomiński A

更新日期：1983-02-01 00:00:00

abstract：:Having a better grasp of the molecular mechanisms underlying carcinogenesis and progression in osteosarcoma would be helpful to find novel therapeutic targets. Different types of cancers have presented abnormal expression of miRNA-101 (miR-101). Nevertheless, we still could not figure out what expression of miR-101 in...

journal_title：Bioscience reports

authors： Lin H,Zheng X,Lu T,Gu Y,Zheng C,Yan H

更新日期：2019-02-08 00:00:00

abstract：:The sodium contents of beta-cell-rich pancreatic islets from ob/ob-mice were measured with an integrating flame photometer. After washing to an apparent steady state with different types of ice-cold media, islets incubated in the absence of glucose contained 79-108 mmol sodium kg-1 dry weight. Exposure to glucose resu...

journal_title：Bioscience reports

authors： Wesslén N,Bergsten P,Hellman B

更新日期：1986-11-01 00:00:00

abstract：:High concentrations of glucose and palmitate increase endothelial cell inflammation and apoptosis, events that often precede atherogenesis. They may do so by decreasing basal autophagy and AMP-activated protein kinase (AMPK) activity, although the mechanisms by which this occurs are not clear. Decreased function of th...

journal_title：Bioscience reports

authors： Weikel KA,Cacicedo JM,Ruderman NB,Ido Y

更新日期：2016-09-16 00:00:00

abstract：:Hippo pathway is a highly conservative signalling pathway related to the development of organisms, which has been demonstrated to be strongly linked to the tumorigenesis and tumour progression. As the major downstream effector of Hippo pathway, yes-associated protein (YAP), is a transcriptional activator of target gen...

journal_title：Bioscience reports

authors： Wang S,Ma K,Chen L,Zhu H,Liang S,Liu M,Xu N

更新日期：2016-09-29 00:00:00

abstract：:In order to better understand the role of cell surface glycolipids in T lymphocyte activation, heparin was used to simultaneously modulate the expression of glycolipids and the lytic capacity of lymphocytes activated by interleukin-2. Results presented here show that heparin added at the start of a 3 day culture inhib...

journal_title：Bioscience reports

authors： Schwarting GA,Gajewski A

更新日期：1988-08-01 00:00:00

abstract：:To the best of our knowledge, this is the first study established a nomogram to predict survival probability in Asian patients with LSCC. A risk prediction nomogram for patients with LSCC, incorporating easily assessable clinicopathologic factors, generates more precise estimations of the survival probability when com...

journal_title：Bioscience reports

authors： Cui J,Wang L,Zhong W,Chen Z,Tan X,Yang H,Chen J,Liu G

更新日期：2020-08-28 00:00:00

abstract：:Phagocytosis by neutrophils, macrophages, and other professional phagocytes requires rapid remodeling of actin. Early phagosomes are surrounded by a rim of F-actin that is disassembled during phagosomoal maturation. Breakdown of periphagosomal F-actin and phagolysosome fusion are calcium dependent processes in neutrop...

journal_title：Bioscience reports

authors： Tejle K,Magnusson KE,Rasmusson B

更新日期：2002-10-01 00:00:00

abstract：:Levels of red cell, serum acid, and alkaline phosphatases, serum amylase, alanine and aspartate transferase and bilirubin were examined in streptozotocin-induced diabetic rats treated with garlic oil and compared with the corresponding levels in diabetic control rats, normal rats and normal rats on garlic oil. Values ...

journal_title：Bioscience reports

authors： Ohaeri OC

更新日期：2001-02-01 00:00:00

abstract：:N-(2-Hydroxypropyl)methacrylamide copolymers bearing oligopeptide side-chains terminating in p-nitroaniline (NAp) were incubated with rat liver lysosomal enzymes in the presence of the thiol glutathione, and the rate of p-nitroaniline release was measured. Twelve of the 16 side-chains investigated were hydrolysed to r...

journal_title：Bioscience reports

authors： Duncan R,Cable HC,Lloyd JB,Rejmanová P,Kopecek J

更新日期：1982-12-01 00:00:00

abstract：:Osteoarthritis (OA) is the most common form of arthritis, and connective tissue growth factor (CTGF) is found to be up-regulated in adjacent areas of cartilage surface damage. CTGF is present in osteophytes of late stage OA. In the present study, we have reviewed association of CTGF in the development and progression ...

journal_title：Bioscience reports

authors： Tu M,Yao Y,Qiao FH,Wang L

更新日期：2019-07-18 00:00:00

abstract：:Particulate membrane fractions from calf liver catalyze the release of glucose from GlcNAc2-Man9-Glc1-3-oligosaccharides. Maximal oligosaccharide-glucosidase activity was obtained at pH 6.2 and a detergent concentration of 0.5% Triton X-100. This activity could be distinguished from non-specific alpha-glucosidase acti...

journal_title：Bioscience reports

authors： Hettkamp H,Bause E,Legler G

更新日期：1982-11-01 00:00:00

abstract：:Specific binding sites for somatostatin have been found in the cytosolic fractions of both parietal and non-parietal cells from rabbit gastric fundic mucosa. The stoichiometric data suggested the presence of two classes of binding sites in both types of cells. The number of low-affinity binding sites was significantly...

journal_title：Bioscience reports

authors： Arilla E,López-Ruiz MP,Gonzalez-Guijarro L,Prieto JC

更新日期：1985-04-01 00:00:00

abstract：:A major cause of failure in chemotherapy is drug resistance of cancer cells. Exosomes have been introduced to spread chemoresistance through delivering miRNAs. However, a systematic evaluation of the exosomal miRNA expression profiles responsible for chemoresistance is still lacking. In the present study, miRNA signat...

journal_title：Bioscience reports

authors： Chen WX,Xu LY,Qian Q,He X,Peng WT,Zhu YL,Cheng L

更新日期：2018-11-15 00:00:00

abstract：:Information on the prevalence and type distribution of human papillomavirus (HPV) among Malaysian women is currently limited. The present study therefore aimed to provide an updated estimate on the prevalence and type distribution of HPV among Malaysian women with and without cervical cancer. Total DNA was isolated fr...

journal_title：Bioscience reports

authors： Tan SC,Ismail MP,Duski DR,Othman NH,Ankathil R

更新日期：2018-03-29 00:00:00

abstract：:The preadipocyte differentiation biological process involves a cascade of transcriptional events that culminates in the expression of peroxisome proliferator-activated receptor (PPAR) γ. The differentiation cocktail [insulin (INS), dexamethasone (DEX) and isobutylmethylxanthine (IBMX)] can induce preadipocyte differen...

journal_title：Bioscience reports

authors： Cheng B,Wu M,Xu S,Zhang X,Wang Y,Wang N,Leng L,Li H

更新日期：2016-11-03 00:00:00

abstract：:Carnosic acid (CA), a major polyphenolic diterpene present in Rosmarinus officinalis, has been reported to have multiple functions, including antitumor activity. The MTT assay, BrdU incorporation, wound healing, and colony formation were used to detect melanoma B16F10 cell growth and proliferation. Flow cytometry was ...

journal_title：Bioscience reports

authors： Lin KI,Lin CC,Kuo SM,Lai JC,Wang YQ,You HL,Hsu ML,Chen CH,Shiu LY

更新日期：2018-07-02 00:00:00