Abstract:
:Specific binding sites for somatostatin have been found in the cytosolic fractions of both parietal and non-parietal cells from rabbit gastric fundic mucosa. The stoichiometric data suggested the presence of two classes of binding sites in both types of cells. The number of low-affinity binding sites was significantly higher in parietal cells than in non-parietal cells. The reverse was true for the high-affinity binding sites. However, the affinity of each class of binding sites was similar in the cytosolic fractions of both parietal and non-parietal cells. It thus appears that low-affinity somatostatin binding sites are mainly located in the parietal cells whereas the high-affinity sites occur principally in the non-parietal cells.
journal_name
Biosci Repjournal_title
Bioscience reportsauthors
Arilla E,López-Ruiz MP,Gonzalez-Guijarro L,Prieto JCdoi
10.1007/BF01116904subject
Has Abstractpub_date
1985-04-01 00:00:00pages
321-8issue
4eissn
0144-8463issn
1573-4935journal_volume
5pub_type
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