Effects of microRNA-211 on proliferation and apoptosis of lens epithelial cells by targeting SIRT1 gene in diabetic cataract mice.

abstract：:Amphiphilic anionic peptides have been used to enhance the efficiency of transfection by helping plasmids to escape from endosomes to the cytosol. It has been shown that efficiency of an eicosamers containing five glutamyl residues (E5), can be considerably enhanced either by transforming it into a dimer or by adding ...

journal_title：Bioscience reports

authors： Freulon I,Monsigny M,Midoux P,Mayer R

更新日期：2000-10-01 00:00:00

abstract：:Superoxide dismutase (SOD), a metal containing enzyme is present in parasite Leishmania donovani as well as in host macrophages both resident and activated in a detectable amount, although the level is much higher in the latter case. It is observed that at any particular protein concentration, the SOD activity is high...

journal_title：Bioscience reports

authors： Mukherjee S,Bandyapadhyay R,Basu MK

更新日期：1988-04-01 00:00:00

abstract：:Signal transducer and activator of transcription (STAT), a family of latent cytoplasmic transcription factors, are composed of seven identified members (STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, STAT6). STATs are associated with several biological processes such as cell proliferation, invasion, and metastasis in var...

journal_title：Bioscience reports

authors： Li S,Sheng B,Zhao M,Shen Q,Zhu H,Zhu X

更新日期：2017-07-16 00:00:00

abstract：:Two established cancer cell lines, MCF-7 and Ishikawa, were both obtained directly from a cell repository and through another laboratory. The karyotypes from the two MCF-7 cell lines had up to 83 chromosomes and similarities for chromosomal gain and structural abnormalities. The two Ishikawa cell lines had up to 60 ch...

journal_title：Bioscience reports

authors： Wenger SL,Senft JR,Sargent LM,Bamezai R,Bairwa N,Grant SG

更新日期：2004-12-01 00:00:00

abstract：:CXCL8, a member of CXC chemokines, was constitutively expressed in many types of human cancers, and its overexpression has been shown to play a critical role in promoting tumorigenesis. The purpose of the present study was to determine CXCL8 expression in a commercial human liver tissue microarray, and elucidate the e...

journal_title：Bioscience reports

authors： Yang S,Wang H,Qin C,Sun H,Han Y

更新日期：2020-08-28 00:00:00

abstract：:Unstable angina pectoris (UA) is one of the most dangerous clinical symptoms of acute coronary syndrome due to the risk of myocardial ischemia, which can lead to high morbidity and mortality worldwide. Though there are many advantages in understanding the pathophysiology of UA, the identification of biomarkers for the...

journal_title：Bioscience reports

authors： Wang J,Xu W,Zhao H,Chen J,Zhu B,Li X,Deng D,Wang J,Liu J,Yu Y,Xiao H,Wang W

更新日期：2019-03-22 00:00:00

abstract：:Whole-genome analyses become more and more necessary for pharmaceutical research. DNA chip hybridizations are an important tool for monitoring gene expression profiles during diseases or medical treatment. However, drug target identification and validation as well as an increasing number of antibodies and other polype...

journal_title：Bioscience reports

authors： Maercker C

更新日期：2005-02-01 00:00:00

abstract：:Neuroblastoma is the most common tumor in children, with a very poor prognosis. It is urgent to identify novel biomarkers to treat neuroblastoma, together with surgery, chemotherapy, and radiation. Human tripartite motif 59 (TRIM59), a member of the TRIM family, has been reported to participate in several human tumors...

journal_title：Bioscience reports

authors： Chen G,Chen W,Ye M,Tan W,Jia B

更新日期：2019-01-18 00:00:00

abstract：:Using both immunohistological study and photoaffinity labelling with radioactive azido-ATP, evidence is presented that the mitochondrial membranes of the brown adipose tissue of the human adult contain a 32 000-Mr uncoupling protein, which is probably similar to the uncoupling protein of BAT of rodents. ...

journal_title：Bioscience reports

authors： Bouillaud F,Combes-George M,Ricquier D

更新日期：1983-08-01 00:00:00

abstract：:The solvation properties of ubiquinone-10 and ubiquinol-10 in a wide variety of solvents of polarity varying from alkanes to water are reported. Greatest solubility is observed in solvents of intermediate polarity and particularly where low polarity is combined with a pronounced tendency to interact with the benzoquin...

journal_title：Bioscience reports

authors： Ondarroa M,Sharma SK,Quinn PJ

更新日期：1986-09-01 00:00:00

abstract：:Ovarian cancer is one of the most common gynecological cancers with a high mortality rate in females. Chromatin target of protein arginine methyltransferase (CHTOP) is an important intracellular protein that regulates the transcriptional activation of several oncogenic genes in glioblastomagenesis and controls mature ...

journal_title：Bioscience reports

authors： Feng X,Li L,Wang L,Luo S,Bai X

更新日期：2019-04-16 00:00:00

abstract：:The existence of cancer stem cells (CSCs) is considered as a direct reason for the failure of clinic treatment in hepatocellular carcinoma (HCC). Growing evidences have demonstrated that miRNAs play an important role in regulation of stem cell proliferation, differentiation and self-renewal and their aberrances cause ...

journal_title：Bioscience reports

authors： Liu Q,Xu Y,Wei S,Gao W,Chen L,Zhou T,Wang Z,Ying M,Zheng Q

更新日期：2015-05-22 00:00:00

abstract：:The present study aimed to evaluate what dosage of gold nanoparticles (GNPs) would improve growth performance, antioxidant levels and immune defense in broiler chickens. The experiment was carried out on 90 one-day-old mixbred Cobb chicks. The birds were allocated into three groups with three replicates. Group (1) kep...

journal_title：Bioscience reports

authors： Hassanen EI,Morsy EA,Hussien AM,Ibrahim MA,Farroh KY

更新日期：2020-03-27 00:00:00

abstract：:Incubation of mouse thymocytes with 10 microM monensin for 1 hour induces morphological alterations characterized by the extensive dilatation and vacuolization of the Golgi complex. This effect is used to study the transport and utilization of labelled sugar nucleotides into intracellular vesicles by using thymocytes ...

journal_title：Bioscience reports

authors： Cecchelli R,Cacan R,Porchet-Hennere E,Verbert A

更新日期：1986-02-01 00:00:00

abstract：:Rabbit reticulocyte lysates, gel filtered on Sephadex G-25 with or without ATP (or its analogs), were preincubated at 37 degrees C and their subsequent binding to p3A4,3'-[32P]pCp was studied. Lysates filtered without ATP or in the presence of 0.1 mM 8-bromo-ATP, 1,N6-etheno-ATP, or ITP showed a time-dependent decreas...

journal_title：Bioscience reports

authors： Wu JM,Wertheimer SJ,Eslami B,Figuereido JC,Goswami BB

更新日期：1985-12-01 00:00:00

abstract：:Mycoplasma pneumoniae is one of the most common pathogenic causes of community-acquired pneumonia. Hydrogen sulfide, alanine, and pyruvate producing enzyme (HapE) is a recently discovered M. pneumoniae virulence factor that can produce H2S to promote erythrocyte lysis. However, other cytotoxic effects of HapE have not...

journal_title：Bioscience reports

authors： Li S,Xue G,Zhao H,Feng Y,Yan C,Cui J,Sun H

更新日期：2019-01-18 00:00:00

abstract：:The purpose of the study is to investigate the correlation between the expression of C-reactive protein (CRP) and autophagy-related 9B (ATG9B) and pathological features of clear cell renal cell carcinoma (CCRCC) patients. We also intended to explore the effects of manipulated expression of CRP and ATG9B on the apoptos...

journal_title：Bioscience reports

authors： Ma Z,Qi Z,Shan Z,Li J,Yang J,Xu Z

更新日期：2017-11-15 00:00:00

abstract：:Facioscapulohumeral muscular dystrophy (FSHD) region gene 1 (FRG1) is a candidate gene for FSHD. FRG1 regulates various muscle-related functions, but studies have proposed its role in development and angiogenesis also, where it is involved with tumor-associated molecules. Therefore, we decided to look into its role in...

journal_title：Bioscience reports

authors： Tiwari A,Pattnaik N,Mohanty Jaiswal A,Dixit M

更新日期：2017-10-27 00:00:00

abstract：:Disc nucleus pulposus (NP) cell experiences periodic osmolarity alterations during daily activities, which has been proved to affect cell biology in vitro The present study was aimed to investigate the effects of cartilage-derived morphogenetic protein-2 (CDMP-2) on NP cell apoptosis under the hyperosmolarity culture ...

journal_title：Bioscience reports

authors： Jiao S,Li J,Liu B,Yang M,Xiu J,Qu D

更新日期：2018-10-09 00:00:00

abstract：:The rate of efflux of L-glutamate from renal brush-border membrane vesicles was enhanced by Na+ and by extravesicular L-glutamate, but not by D-glutamate nor analogs of L-glutamate that do not share the Na+-L-glutamate co-transport system. These results suggest that efflux was mediated by the Na+-L-glutamate carrier. ...

journal_title：Bioscience reports

authors： Sacktor B,Lepor N,Schneider EG

更新日期：1981-09-01 00:00:00

abstract：:Chitinases catalyze the degradation of chitin, a ubiquitous polymer generated from the cell walls of fungi, shells of crustaceans, and cuticles of insects. They are gaining increasing attention in medicine, agriculture, food and drug industries, and environmental management. Their roles in the degradation of chitin fo...

journal_title：Bioscience reports

authors： Oyeleye A,Normi YM

更新日期：2018-08-29 00:00:00

abstract：:Coagulation factor IX (FIX) is an essential plasma protein for blood coagulation. The first epidermal growth factor (EGF) motif of FIX (EGF-F9) has been reported to attenuate cell adhesion to the extracellular matrix (ECM). The purpose of the present study was to determine the effects of this motif on cell adhesion an...

journal_title：Bioscience reports

authors： Ishikawa T,Kitano H,Mamiya A,Kokubun S,Hidai C

更新日期：2016-06-03 00:00:00

abstract：:Heterotopic ossification (HO) is the aberrant formation of mature, lamellar bone in nonosseous tissue. Fibrodysplasia ossificans progressiva (FOP) is a rare and devastating genetic disorder that causes progressive HO in the ligaments, tendons, and muscles throughout the body. FOP is attributed to an autosomal mutation...

journal_title：Bioscience reports

authors： Lin H,Shi F,Gao J,Hua P

更新日期：2019-08-02 00:00:00

abstract：:Three genotypically suppressible alleles, a1X4, alcA125, and niaD500, are phenotypically suppressed by aminoglycoside antibiotics. Unsuppressible alleles at these loci are unaffected as are known missense mutations at the yA and gdhA loci. This is consistent with the premise that the suppressible mutations are nonsens...

journal_title：Bioscience reports

authors： Martinelli SD,Roberts TJ

更新日期：1983-01-01 00:00:00

abstract：:The concentration of carbonic anhydrase III (CAIII) in male rat liver was found to be 30 times greater than that in the female. Castration of male rats led to marked reduction in liver CAIII concentrations which could be partially restored to control levels by testosterone replacement. Marked developmental and senesce...

journal_title：Bioscience reports

authors： Shiels A,Jeffery S,Phillips IR,Shephard EA,Wilson CA,Carter ND

更新日期：1983-05-01 00:00:00

abstract：:Down-regulation of p16INK4a and miR-146b-5p contributes to tumorigenesis in osteosarcoma (OS). However, the correlation between p16INK4a and miR-146b-5p in OS proliferation remains largely unknown. In the present study, we demonstrated that miR-146b-5p expression was positively correlated with p16INK4a in OS, but inve...

journal_title：Bioscience reports

authors： Jiang M,Lu W,Ding X,Liu X,Guo Z,Wu X

更新日期：2019-02-01 00:00:00

abstract：:Background: Urotensin-II (UII) rs228648 polymorphism has been reported to be associated with the risk of diabetes mellitus (DM) with inconsistent results. The present study sought to reassess the relationship between this polymorphism and susceptibility to DM by meta-analysis.Methods: Relevant eligible studies and who...

journal_title：Bioscience reports

authors： Zhao Y,Fang S,Que K,Xu G,Zhang H,Qi C,Yang N

更新日期：2018-12-07 00:00:00

abstract：:Previous studies demonstrated that the adaptive response to stressors and inflammatory signals involves the activation of the autonomous [corrected] nervous system. Catecholamines have been shown to modulate the activity of various immune effector cells directly via membrane adrenergic receptors. Here, we investigated...

journal_title：Bioscience reports

authors： Lünemann JD,Buttgereit F,Tripmacher R,Baerwald CG,Burmester GR,Krause A

更新日期：2001-10-01 00:00:00

abstract：:Acquired resistance of afatinib is a significant challenge for non-small cell lung cancer (NSCLC) therapy and the mechanisms remain unclear. Aberrant activation of epidermal growth factor receptor (EGFR)-dependent downstream pathways, especially phosphatidylinositol-3-kinases/protein kinase B (PI3K/Akt) signaling path...

journal_title：Bioscience reports

authors： Li B,Yuan Z,Jiang J,Rao Y

更新日期：2018-12-11 00:00:00

abstract：:Sendai virus envelopes (SVE) were isolated from Sendai virus particles by Triton X-100 solubilization and ultracentrifugation. The envelopes were reconstituted in the presence of the fluorescent dye calcein by gradual removal of the detergent with Bio-beads SM-2. The internal volume of reconstituted Sendai virus envel...

journal_title：Bioscience reports

authors： Bartzatt RL,Volsky DJ

更新日期：1984-07-01 00:00:00