Some properties of 2-5A binding/nucleolytic activities in gel filtered rabbit reticulocyte lysates.

abstract：:Homologues of the putative dehydrogenase YjhC are found in operons involved in the metabolism of N-acetylneuraminate (Neu5Ac) or related compounds. We observed that purified recombinant YjhC forms Neu5Ac from two dehydrated forms of this compound, 2,7-anhydro-N-acetylneuraminate (2,7-AN) and 2-deoxy-2,3-didehydro-N-ac...

journal_title：Bioscience reports

authors： Kentache T,Thabault L,Peracchi A,Frédérick R,Bommer GT,Van Schaftingen E

更新日期：2020-06-26 00:00:00

abstract：OBJECTIVE:Gastric cancer is the most common gastrointestinal malignancy in China and results from a combination of genetic and environmental factors. The present study was conducted to investigate the relationship between long noncoding RNA (lncRNA) materally expressed gene 3 (MEG3) single nucleotide polymorphisms (SNP...

journal_title：Bioscience reports

authors： Kong X,Yang S,Liu C,Tang H,Chen Y,Zhang X,Zhou Y,Liang G

更新日期：2020-11-27 00:00:00

abstract：:Intracellular lipid-binding proteins (iLBPs) of the fatty acid-binding protein (FABP) family of animals transport, mainly fatty acids or retinoids, are confined to the cytosol and have highly similar 3D structures. In contrast, nematodes possess fatty acid-binding proteins (nemFABPs) that are secreted into the perivit...

journal_title：Bioscience reports

authors： Ibáñez-Shimabukuro M,Rey-Burusco MF,Gabrielsen M,Franchini GR,Riboldi-Tunnicliffe A,Roe AJ,Griffiths K,Cooper A,Córsico B,Kennedy MW,Smith BO

更新日期：2019-07-23 00:00:00

abstract：:N-(2-Hydroxypropyl)methacrylamide copolymers bearing oligopeptide side-chains terminating in p-nitroaniline (NAp) were incubated with rat liver lysosomal enzymes in the presence of the thiol glutathione, and the rate of p-nitroaniline release was measured. Twelve of the 16 side-chains investigated were hydrolysed to r...

journal_title：Bioscience reports

authors： Duncan R,Cable HC,Lloyd JB,Rejmanová P,Kopecek J

更新日期：1982-12-01 00:00:00

abstract：:Three myoid-cell clones were established from the thymuses of two Wistar rats; one thymus yielded two clones, R615A and R615B2, and the other yielded one clone, R613Ad. The three clones were divided into two subtypes. Both subtypes were able to form myofibrils, expressed AChR on their cell-surface membrane, and contai...

journal_title：Bioscience reports

authors： Kamo I,Nonaka I,Furukawa S,Satoyoshi E

更新日期：1984-11-01 00:00:00

abstract：:Osteoarthritis (OA) is one of the most common chronic joint disease. Long non-coding RNAs (lncRNAs) have been confirmed to play important roles in a variety of diseases including OA. However, the underlying mechanism of lncRNA differentiation antagonizing non-protein coding RNA (DANCR) in OA has not been well elucidat...

journal_title：Bioscience reports

authors： Zhang L,Zhang P,Sun X,Zhou L,Zhao J

更新日期：2018-12-14 00:00:00

abstract：:The concentration of Na+ and K+ and the pH in the cytoplasm of Lettré cells was measured by monitoring the net flux of H+, Na+, or K+ across the plasma membrane which had been rendered permeable to these ions by the action of Sendai virus. Ion flux was measured directly by analysis of cell composition, or indirectly b...

journal_title：Bioscience reports

authors： Bashford CL,Alder G,Micklem KJ,Pasternak CA

更新日期：1983-07-01 00:00:00

abstract：:The discovery of genes that control cell division in yeast, and their relation to cancer, is reviewed. ...

journal_title：Bioscience reports

authors： Hartwell LH

更新日期：2002-06-01 00:00:00

abstract：:Prostate cancer (PCa), the second most mortal cancer from developed countries, presents a high level of chemoresistance. There is emerging evidence underscores the critical role of autophagy in the onset, progression, and chemoresistance of PCa. In the present study, we investigated the possible role of a novel autoph...

journal_title：Bioscience reports

authors： Liu J,Chen Z,Guo J,Wang L,Liu X

更新日期：2019-08-23 00:00:00

abstract：:Glycine methyl ester, an inhibitor of transglutaminase, decreased glucose-stimulated insulin release and delayed proinsulin conversion in rat pancreatic islets pulse-labelled with L-[4-3H]phenylalanine. Sarcosine methyl ester, which does not inhibit transglutaminase activity, failed to affect insulin release and proin...

journal_title：Bioscience reports

authors： Alarcon C,Valverde I,Malaisse WJ

更新日期：1985-07-01 00:00:00

abstract：:The first demonstration of a method to incorporate radiolabeled methyl groups from [14C]formaldehyde into membrane proteins in human erythrocytes by reductive methylation in the presence of NaCNBH3 is described. This method is based on the work of Jentoft and Dearborn [(1979) J. Biol. Chem. 254, 4359-4365], who demons...

journal_title：Bioscience reports

authors： Butterfield DA,Shahabuddin M

更新日期：1982-04-01 00:00:00

abstract：AIM:To explore the prognostic value of clusterin (CLU) in hepatocellular carcinoma (HCC) patients treated with oxaliplatin (OXA). METHODS:Relative expression of plasma CLU mRNA was examined via fluorescence quantitative real-time PCR (qRT-PCR), and CLU protein level in tissue samples was detected through immunohistoch...

journal_title：Bioscience reports

authors： Wang X,Liu Y,Qin Q,Zheng T

更新日期：2020-02-28 00:00:00

abstract：:Mitochondria are known to participate in the initiation of programmed cell death (PCD) in animals and in plants. The role of chloroplasts in PCD is still unknown. We describe a new system to study PCD in plants; namely, leaf epidermal peels. The peel represents a monolayer consisting of cells of two types: phototrophi...

journal_title：Bioscience reports

authors： Samuilov VD,Lagunova EM,Kiselevsky DB,Dzyubinskaya EV,Makarova YV,Gusev MV

更新日期：2003-04-01 00:00:00

abstract：:We aimed to determine the effect of 'Xiaozeng No. 1' (XZ-1) on cellular apoptosis changes of gastric epithelial dysplasia (GED) and to explore the underlying mechanism. Specimens taken from the pyloric area of the stomachs from rats in each group were subjected to Hematoxylin and Eosin (H&E) staining for pathological ...

journal_title：Bioscience reports

authors： Xu B,Zhang AM,Li F,Cui M,Han J,Cao Q

更新日期：2018-06-12 00:00:00

abstract：:When the amino-acid sequence of the 108-residue, rat tumour calcium-binding protein, oncomodulin, was aligned with that of rat muscle parvalbumin, 55 homologous positions were found, with an additional 33 single base-pair substitutions. This extensive homology, with virtual identity of the calcium-binding domains, sig...

journal_title：Bioscience reports

authors： MacManus JP,Watson DC,Yaguchi M

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:Annulus fibrosus (AF) is important to confine disc nucleus pulposus (NP) tissue during mechanical load experience. However, the knowledge on AF cell biology under mechanical load is much limited compared with disc NP. OBJECTIVE:The present study aimed to investigate responses of apoptosis and matrix metabol...

journal_title：Bioscience reports

authors： Jiang Y,Fu L,Song Y

更新日期：2019-02-22 00:00:00

abstract：:Calmodulin (CaM)-like activity was detected in human serum and foetal calf serum, with an activity 10 times more than that detectable in plasma. Serum CaM was largely accounted for by release from human platelets as confirmed by both radioimmunoassay and sodium-dodecyl-sulphate/polyacrylamide-gel electrophoresis of Ca...

journal_title：Bioscience reports

authors： Mac Neil S,Walker SW,Seid J,Tomlinson S

更新日期：1984-08-01 00:00:00

abstract：:Information on the prevalence and type distribution of human papillomavirus (HPV) among Malaysian women is currently limited. The present study therefore aimed to provide an updated estimate on the prevalence and type distribution of HPV among Malaysian women with and without cervical cancer. Total DNA was isolated fr...

journal_title：Bioscience reports

authors： Tan SC,Ismail MP,Duski DR,Othman NH,Ankathil R

更新日期：2018-03-29 00:00:00

abstract：:The emergence of multidrug-resistant (MDR) microbes caused by overuse of antibiotics leads to urgent demands for novel antibiotics exploration. Our recent data showed that Ly2.1-3 (a novel lymphocyte antigen 6 (Ly6) gene cluster) were proteins with cationic nature and rich in cysteine content, that are characteristic ...

journal_title：Bioscience reports

authors： Liu X,Cao X,Wang S,Ji G,Zhang S,Li H

更新日期：2017-01-17 00:00:00

abstract：:Hippo pathway is a highly conservative signalling pathway related to the development of organisms, which has been demonstrated to be strongly linked to the tumorigenesis and tumour progression. As the major downstream effector of Hippo pathway, yes-associated protein (YAP), is a transcriptional activator of target gen...

journal_title：Bioscience reports

authors： Wang S,Ma K,Chen L,Zhu H,Liang S,Liu M,Xu N

更新日期：2016-09-29 00:00:00

abstract：:Native bovine parathyroid hormone (bPTH) was found to be readily cleaved with human leukocyte elastase to yield the fragments bPTH(1-41) and bPTH(42-84). These were then isolated by reverse-phase HPLC and characterised by gas-phase sequencing and amino acid analysis. The biological activities of these fragments were a...

journal_title：Bioscience reports

authors： Barling PM,Lowe C

更新日期：1987-01-01 00:00:00

abstract：:Background: Single-nucleotide polymorphisms (SNPs) in lncRNAs could be biomarkers for susceptibility to colorectal cancer (CRC), but the association of PCAT1 polymorphisms and CRC susceptibility is yet to be studied. Methods: Five tagSNPs covering the PCAT1 gene were detected through Kompetitive Allele-Specific PCR am...

journal_title：Bioscience reports

authors： Yang ML,Huang Z,Wu LN,Wu R,Ding HX,Wang BG

更新日期：2019-07-12 00:00:00

abstract：:Activatable cell-penetrating peptides (aCPPs) allow non-viral, low cytotoxic and selective delivery of compounds into target cells for cancer therapy. In tumour cells, up-regulation of human telomerase reverse transcriptase (hTERT) frequently occurs and is being considered as a target in cancer diagnosis and treatment...

journal_title：Bioscience reports

authors： Li H,He J,Yi H,Xiang G,Chen K,Fu B,Yang Y,Chen G

更新日期：2015-03-18 00:00:00

abstract：:Tuberculosis (TB) is a chronic infectious disease that has been threatening public health for many years. Several studies have shown the relationship between the macrophage migration inhibitory factor (MIF)-794 CATT (MIF-794 CATT) microsatellite polymorphism and susceptibility to TB. However, the results remain inconc...

journal_title：Bioscience reports

authors： Ma M,Tao L,Liu A,Liang Z,Yang J,Peng Y,Dai X,Bai R,Ji Z,Jian M,Bao F

更新日期：2018-07-06 00:00:00

abstract：:Interleukin-21 (IL-21) is a cytokine that plays a crucial role in pathogenesis and activity of the rheumatoid arthritis (RA). Meanwhile, genetic polymorphisms in the IL-21 gene may alter its expression. Previous studies have reported conflicting results assessing the association between the IL-21 rs6822844 G/T polymor...

journal_title：Bioscience reports

authors： Yu M,Hou J,Zheng M,Cao Y,Alike Y,Mi Y,Zhu J

更新日期：2020-01-31 00:00:00

abstract：:Virus replication inhibitory peptide (carbobenzoxy-D-Phe-L-PheGly) was shown to be a potent specific inhibitor of the replication of paramyxovirus and myxovirus (Richardson, Scheid and Choppin (1980), Virology 105, 205-222). This peptide inhibits the membrane fusing activity of a viral glycoprotein. Many agents which ...

journal_title：Bioscience reports

authors： Epand RM

更新日期：1986-07-01 00:00:00

abstract：:Huaier Granule, a type of traditional Chinese biomedical preparation (TCBP), is considered to be a promising adjuvant therapy for breast cancer. Although an analysis of the published literature has been performed, the exact effects and safety of Huaier Granule remains controversial. Therefore, a wide-ranging systemati...

journal_title：Bioscience reports

authors： Yao X,Wu W,Qu K,Xi W

更新日期：2020-08-28 00:00:00

abstract：:Our study aimed at exploring the effects of miR-211 on the proliferation and apoptosis of lens epithelial cells in diabetic cataract mice by targetting NAD+-dependent histone deacetylase sirtulin 1 (SIRT1). Healthy male mice were assigned into normal and diabetic cataract groups. Blood glucose, lens turbidity, and apo...

journal_title：Bioscience reports

authors： Zeng K,Feng QG,Lin BT,Ma DH,Liu CM

更新日期：2017-07-27 00:00:00

abstract：:An increase in the permeability of outer mitochondrial membrane is central to apoptotic cell death, and results in the release of several apoptogenic factors such as cytochrome c into the cytoplasm to activate downstream destructive programs. The voltage-dependent anion channel (VDAC or mitochondrial porin) plays an e...

journal_title：Bioscience reports

authors： Tsujimoto Y

更新日期：2002-02-01 00:00:00

abstract：:The effect of ligands (glucose, ATP and Mg2+) and zwitterionic micelles of lysophosphatidylcholine (LPC) or N-hexadecyl-N,N-dimethyl-3-ammonium propanesulfonate (HPS) in the yeast hexokinase (HK) stability was studied at 35 degrees C. The thermal inactivation kinetics followed one-exponential decay. The effect of liga...

journal_title：Bioscience reports

authors： Guerra R,Bianconi ML

更新日期：2000-02-01 00:00:00