Abstract:
:The concentration of carbonic anhydrase III (CAIII) in male rat liver was found to be 30 times greater than that in the female. Castration of male rats led to marked reduction in liver CAIII concentrations which could be partially restored to control levels by testosterone replacement. Marked developmental and senescence changes in liver CAIII were also observed in male rats.
journal_name
Biosci Repjournal_title
Bioscience reportsauthors
Shiels A,Jeffery S,Phillips IR,Shephard EA,Wilson CA,Carter NDdoi
10.1007/BF01121959subject
Has Abstractpub_date
1983-05-01 00:00:00pages
475-8issue
5eissn
0144-8463issn
1573-4935journal_volume
3pub_type
杂志文章abstract::We have investigated a novel method to monitor real changes of intracellular ROS by the use of CMH2TMRos (a reduced form of MitoTracker orange) in Swiss 3T3 fibroblasts. Arachidonic acid induced a rapid increase of CMTMRos fluorescence with a maximal elevation at 120-150 sec, which was determined by scanning every 10 ...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1023/a:1013290316939
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abstract::Mice and rats are animals commonly used in research and laboratory testing. Compared with other animal species, they harbor many more zoonotic agents. Hymenolepis nana (H. nana) is a common tapeworm that parasitizes both humans and rodents. Although this tapeworm is of socio-economic importance worldwide, information ...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20181224
更新日期:2019-02-08 00:00:00
abstract::Radiotherapy is the primary treatment option for nasopharyngeal carcinoma (NPC). Local recurrence and metastasis caused by radioresistance become a bottleneck of curative effect for patients with NPC. Currently, serum predictive biomarkers of radioresistance are scare. We enrolled NPC patients, who underwent radiother...
journal_title:Bioscience reports
pub_type: 杂志文章
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abstract::Lung surfactant protein A (SP-A) is the most abundant surfactant-associated protein present in the lung. A receptor for SP-A has been shown to be present on A549 alveolar type II cells and on other cell types, including alveolar macrophage. The SP-A receptor on A549 cells has been identified as the collection receptor...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1007/BF01145960
更新日期:1993-04-01 00:00:00
abstract::Aim: In previous studies, numerous dysregulated long non-coding RNAs (lncRNAs) were identified by RNA-sequencing (RNA-seq). However, the relationship between lncRNA and osteosarcoma remains unclear. In the present study, the function and mechanism of lncRNA BE503655 were investigated. Methods: Transwell, cell cycle an...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20182200
更新日期:2019-07-29 00:00:00
abstract::To investigate whether the human anti-thrombospondin type 1 domain-containing 7A (THSD7A) antibody-induced membranous nephropathy (MN) is mediated by activating lectin complement pathway. Automatic biochemical apparatus was used to assess renal function of mice. The serum levels of anti-THSD7A antibodies and complemen...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20180131
更新日期:2018-06-21 00:00:00
abstract::Pulmonary arterial hypertension (PAH) is a life-threatening chronic cardiopulmonary disorder. However, studies providing PAH-related gene expression profiles are scarce. To identify hub genes involved in PAH, we investigate two microarray data sets from gene expression omnibus (GEO). A total of 150 differentially expr...
journal_title:Bioscience reports
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journal_title:Bioscience reports
pub_type: 杂志文章,评审
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更新日期:2019-08-02 00:00:00
abstract::Lung adenocarcinoma (LUAD) is the leading cause of cancer-related death worldwide, and its underlying mechanism remains unclear. Accumulating evidence has highlighted that long non-coding RNA (lncRNA) acts as competitive endogenous RNA (ceRNA) and plays an important role in the occurrence and development of LUAD. Here...
journal_title:Bioscience reports
pub_type: 杂志文章
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journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20200079
更新日期:2020-03-27 00:00:00
abstract::Prognostic significance of family with sequence similarity 83, member D (FAM83D) in hepatocellular carcinoma (HCC) patients has not been well-investigated using Gene Expression Omnibus (GEO) series and TCGA database, we compared FAM83D expression levels between tumor and adjacent tissues, and correlated FAM83D in tumo...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20181640
更新日期:2019-05-07 00:00:00
abstract::Down-regulation of p16INK4a and miR-146b-5p contributes to tumorigenesis in osteosarcoma (OS). However, the correlation between p16INK4a and miR-146b-5p in OS proliferation remains largely unknown. In the present study, we demonstrated that miR-146b-5p expression was positively correlated with p16INK4a in OS, but inve...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20181268
更新日期:2019-02-01 00:00:00
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journal_title:Bioscience reports
pub_type: 杂志文章,评审
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abstract::For improving Ostwald's viscometry, which is time-consuming and requires a relatively large volume of specimen to determine viscosity, we developed a capillary microviscometric method with an appropriate mathematical model, and have compared this method with Ostwald's method. ...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1007/BF01121952
更新日期:1983-02-01 00:00:00
abstract::Endothelin-1 (ET-1) and plasminogen activator inhibitor-1 (PAI-1) play important roles in pulmonary hypertension (PH) in sickle cell disease (SCD). Our previous studies show higher levels of placenta growth factor (PlGF) in SCD correlate with increased plasma levels of ET-1, PAI-1, and other physiological markers of P...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20150190
更新日期:2015-10-12 00:00:00
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journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1007/BF01114972
更新日期:1986-11-01 00:00:00
abstract::Canstatin, the non-collagenous domain of collagen type IV α-chains, belongs to a series of collagen-derived angiogenic inhibitors. In this study, the inhibitory effect of recombinant canstatin on tumour growth was investigated using a gastric cancer xenograft model. The volume and weight of tumours in mice treated wit...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20140012
更新日期:2014-04-01 00:00:00
abstract::We assessed the relationship between the volume of epicardial adipose tissue and long-term outcomes in patients with coronary heart disease (CHD) undergoing percutaneous coronary intervention (PCI). The patients with CHD were followed for at least 2 years after PCI. The epicardial adipose tissue volume (EATV) was meas...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20182278
更新日期:2019-05-07 00:00:00
abstract::Using a quantitative enzyme immunoassay, Thy-1 antigen expressed by a rat myoid cell line R615B2 was detected mainly on the cell surface at a single cell stage, whereas at the stage of forming myotubes, Thy-1 was found predominantly in the cytoplasm. The muscle specific creatine kinase activity also increased in assoc...
journal_title:Bioscience reports
pub_type: 杂志文章
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更新日期:1989-10-01 00:00:00
abstract::To clarify the mechanism of circGOLPH3 regulation on prostate cancer cells, we performed an overexpression and interference circGOLPH3 assay in prostate cancer cells PC-3 and then evaluated cellular viability, proliferation, cell cycle, and apoptosis of prostate cancer cells by MTT, CCK8, Edu stain, TUNEL stain, and f...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20200936
更新日期:2020-12-23 00:00:00
abstract::Whole-genome analyses become more and more necessary for pharmaceutical research. DNA chip hybridizations are an important tool for monitoring gene expression profiles during diseases or medical treatment. However, drug target identification and validation as well as an increasing number of antibodies and other polype...
journal_title:Bioscience reports
pub_type: 杂志文章,评审
doi:10.1007/s10540-005-2848-y
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journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20181658
更新日期:2019-03-22 00:00:00
abstract:BACKGROUND:Emerging evidences have indicated that long non-coding RNAs (LncRNAs) play vital roles in cancer development and progression. Previous studies have suggested that overexpression of SPRY4 intronic transcript 1 (SPRY4-IT1) predicates poor prognosis and promotes tumor progress in cervical cancer (CC). However, ...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20181339
更新日期:2019-06-04 00:00:00
abstract::Corneal inflammation or keratitis is a significant cause of ocular morbidity around the world. Fortunately, the majority of the cases are successfully managed with medical therapy, but the failure of therapy does occur, leading to devastating consequences of either losing the vision or the eye. This review attempts to...
journal_title:Bioscience reports
pub_type: 杂志文章,评审
doi:10.1023/a:1017939725776
更新日期:2001-08-01 00:00:00
abstract::Peri-implantitis, which is characterized by dense inflammatory infiltrates and increased osteoclast activity, can lead to alveolar bone destruction and implantation failure. miRNAs participate in the regulation of various inflammatory diseases, such as periodontitis and osteoporosis. Therefore, the present study aimed...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20170768
更新日期:2017-10-11 00:00:00
abstract::BRL 26830 is a thermogenic beta-adrenoceptor agonist which stimulates lipolysis and fatty acid oxidation in vivo. It also stimulates insulin secretion, and hence promotes glucose utilisation in vivo. The effect of this agent on white and brown adipose tissue of the rat was investigated. BRL 26830 increased the rate of...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1007/BF01117517
更新日期:1989-02-01 00:00:00
abstract::Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening meningitis primarily in immunocompromised individuals. In order to survive and proliferate during infection, C. neoformans must adapt to a variety of stresses it encounters within the host. Patient outcome depends on the interacti...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20190337
更新日期:2020-10-30 00:00:00
abstract::Alterations in genomic CpG methylation patterns have been found to be associated with cell transformation and neoplasia. Although it is recognized that methylation of CpG residues negatively regulates gene expression, how the various MBPs (methyl-binding proteins) contribute to this process remains elusive. To determi...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20080032
更新日期:2008-12-01 00:00:00
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journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1042/BSR20192666
更新日期:2020-01-31 00:00:00
abstract::In order to better understand the role of cell surface glycolipids in T lymphocyte activation, heparin was used to simultaneously modulate the expression of glycolipids and the lytic capacity of lymphocytes activated by interleukin-2. Results presented here show that heparin added at the start of a 3 day culture inhib...
journal_title:Bioscience reports
pub_type: 杂志文章
doi:10.1007/BF01115230
更新日期:1988-08-01 00:00:00