Abstract:
:Three myoid-cell clones were established from the thymuses of two Wistar rats; one thymus yielded two clones, R615A and R615B2, and the other yielded one clone, R613Ad. The three clones were divided into two subtypes. Both subtypes were able to form myofibrils, expressed AChR on their cell-surface membrane, and contained myofibrillar ATPase characteristic of undifferentiated type-2C fibers, but they differed from each other in morphology, expression of Thy 1 antigen, spontaneous contractility, and qualitative accumulation of AChR. Immunolocalization studies using antisera against the respective cell subtypes also indicated regional differences in their cellular origin. These results show that the thymus contains heterogenous myoid-cell precursors.
journal_name
Biosci Repjournal_title
Bioscience reportsauthors
Kamo I,Nonaka I,Furukawa S,Satoyoshi Edoi
10.1007/BF01116890subject
Has Abstractpub_date
1984-11-01 00:00:00pages
925-32issue
11eissn
0144-8463issn
1573-4935journal_volume
4pub_type
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